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The map label for this gene is adh [H]

Identifier: 119716590

GI number: 119716590

Start: 2518792

End: 2519856

Strand: Reverse

Name: adh [H]

Synonym: Noca_2363

Alternate gene names: 119716590

Gene position: 2519856-2518792 (Counterclockwise)

Preceding gene: 119716593

Following gene: 119716588

Centisome position: 50.54

GC content: 74.55

Gene sequence:

>1065_bases
GTGCAGGCTCTCAGGTTGCGCGCATGGAAGTCCGACCCGGTGCTCGAGGACGTCGCCGTCCCCGAACCGGGCCCCGACGA
GGTCCTGGTCCAGGTGGGAGGTGCGGGCGCCTGCCACTCCGACCTGCACCTGATGCACGAGTTCGAGCCCGGGACGCTGC
CCTGGTCCCCGCCGTTCACGCTCGGCCACGAGAACGCCGGCTGGGTGCACACCGTCGGCACCGGGGTCACCGGGCTCGAG
CCCGGCCAGCCGGTCGCCGTGGTCGGGGCCTGGGGCTGCGGCGTCTGCGACCGCTGCCGCGCAGGTGTCGAGACCTACTG
CGAGCGCCCCGACCTGGCACCCGTGCCGTCCGGCGGCGGGGGTCTCGGCCTGGACGGCGGGATGGCGGAGTACCTCCTGG
TGCGCGGCGCGCGACACGTCGTTCCGCTGCCTGAGGGCCTCGACCCGGTGACCGCCGCTCCACTGACCGACGCAGGCCTC
ACGCCCTACCACGCCGTGCGACGCTCGCTCGCGAAGCTGGCGCCCGGCGCCACCGCGCTGGTCATCGGCGTCGGCGGGCT
CGGCCACCTCGGCGTCCAGGTGCTCCGTGCTGTCACGGCCGCCCGGGTGATCGCTGTCGACCCGCGCTCCTCCGCGCTGA
GCCTGGCCTCGAAGGTGGGTGCCGACGCCACGCTCACCCCCGGACCCGCCACGGCGGCGGAGGTCCGTGAGCTCACCCAC
GGGGTCGGCGCGGACGTCGTGCTGGACTTCGTCGGCTCGGACGACACGCTGGCCCTGGCCGCCCAGGCGGTCCGCCAGCT
CGGGGACCTCACCGTCGTCGGCATCGCCGGCGGCAGCCTGCCGTTCTCCTTCTTCGGCGTCCCCTACGAGTGCAGCGTGC
AGACGACGTACTGGGGCAACCGGACCGAGCTGGTCGAGGTTCTCGACCTCGCGGCGCGGGGCCTGCTCACCGCACACACC
ACGACCTTCGAGCTCGCGCAGGCACCCGAGGTCTACGCCGAGCTGGCCCGCGGCGAGATCGACGGGCGGGCGGTGGTGGT
GCCCAACCGGGCCTACCGGCCCTGA

Upstream 100 bases:

>100_bases
TCGGGACCTTCGTCTCCCCCGGTTGGTGCCCCGGGCCTCGTGCGCTGACGCCGGCATCCGCGCAGACTGCGAGCATCGAC
TCGTACCGGAGGTGGGAGCG

Downstream 100 bases:

>100_bases
GCCCCGGGCTGGCTGCCGGGCTTGCTGCCCGGTCGCGGCCCCGGTTTGGTCTCCGCGGTCGCGGCCAGCCAGGCGCGGAA
CCGGCGCGGGTCGCGACGCT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQALRLRAWKSDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFTLGHENAGWVHTVGTGVTGLE
PGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVPSGGGGLGLDGGMAEYLLVRGARHVVPLPEGLDPVTAAPLTDAGL
TPYHAVRRSLAKLAPGATALVIGVGGLGHLGVQVLRAVTAARVIAVDPRSSALSLASKVGADATLTPGPATAAEVRELTH
GVGADVVLDFVGSDDTLALAAQAVRQLGDLTVVGIAGGSLPFSFFGVPYECSVQTTYWGNRTELVEVLDLAARGLLTAHT
TTFELAQAPEVYAELARGEIDGRAVVVPNRAYRP

Sequences:

>Translated_354_residues
MQALRLRAWKSDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFTLGHENAGWVHTVGTGVTGLE
PGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVPSGGGGLGLDGGMAEYLLVRGARHVVPLPEGLDPVTAAPLTDAGL
TPYHAVRRSLAKLAPGATALVIGVGGLGHLGVQVLRAVTAARVIAVDPRSSALSLASKVGADATLTPGPATAAEVRELTH
GVGADVVLDFVGSDDTLALAAQAVRQLGDLTVVGIAGGSLPFSFFGVPYECSVQTTYWGNRTELVEVLDLAARGLLTAHT
TTFELAQAPEVYAELARGEIDGRAVVVPNRAYRP
>Mature_354_residues
MQALRLRAWKSDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFTLGHENAGWVHTVGTGVTGLE
PGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVPSGGGGLGLDGGMAEYLLVRGARHVVPLPEGLDPVTAAPLTDAGL
TPYHAVRRSLAKLAPGATALVIGVGGLGHLGVQVLRAVTAARVIAVDPRSSALSLASKVGADATLTPGPATAAEVRELTH
GVGADVVLDFVGSDDTLALAAQAVRQLGDLTVVGIAGGSLPFSFFGVPYECSVQTTYWGNRTELVEVLDLAARGLLTAHT
TTFELAQAPEVYAELARGEIDGRAVVVPNRAYRP

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=279, Percent_Identity=28.673835125448, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4501933, Length=279, Percent_Identity=29.3906810035842, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501929, Length=282, Percent_Identity=28.3687943262411, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI156627571, Length=334, Percent_Identity=27.5449101796407, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501939, Length=306, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI156523966, Length=306, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI262073058, Length=280, Percent_Identity=25.3571428571429, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI71743840, Length=280, Percent_Identity=25.3571428571429, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI71565154, Length=269, Percent_Identity=26.3940520446097, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=33.9506172839506, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788073, Length=291, Percent_Identity=29.553264604811, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082125, Length=354, Percent_Identity=29.0960451977401, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788407, Length=350, Percent_Identity=29.1428571428571, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI226510992, Length=335, Percent_Identity=29.8507462686567, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786518, Length=343, Percent_Identity=29.1545189504373, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790045, Length=293, Percent_Identity=26.6211604095563, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790718, Length=261, Percent_Identity=28.3524904214559, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788075, Length=280, Percent_Identity=27.5, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786552, Length=277, Percent_Identity=28.8808664259928, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786825, Length=382, Percent_Identity=25.9162303664921, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787863, Length=316, Percent_Identity=27.5316455696203, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082401, Length=145, Percent_Identity=36.551724137931, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=341, Percent_Identity=29.9120234604106, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988145, Length=354, Percent_Identity=28.5310734463277, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562582, Length=356, Percent_Identity=27.8089887640449, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17562876, Length=343, Percent_Identity=27.1137026239067, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=343, Percent_Identity=26.530612244898, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25146526, Length=294, Percent_Identity=25.1700680272109, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=296, Percent_Identity=25.3378378378378, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=261, Percent_Identity=23.3716475095785, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=339, Percent_Identity=31.2684365781711, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323961, Length=346, Percent_Identity=32.3699421965318, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319621, Length=352, Percent_Identity=31.8181818181818, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=31.4868804664723, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319258, Length=325, Percent_Identity=27.3846153846154, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=288, Percent_Identity=26.0416666666667, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=354, Percent_Identity=25.4237288135593, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=279, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=279, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319257, Length=283, Percent_Identity=27.5618374558304, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323980, Length=343, Percent_Identity=26.2390670553936, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737895, Length=367, Percent_Identity=26.158038147139, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17137530, Length=261, Percent_Identity=28.3524904214559, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737897, Length=261, Percent_Identity=28.3524904214559, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36507; Mature: 36507

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALRLRAWKSDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFT
CCCCEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCCCCCCCCCC
LGHENAGWVHTVGTGVTGLEPGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVPSGGG
CCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHCHHHHHCCCCCCCCCCCCC
GLGLDGGMAEYLLVRGARHVVPLPEGLDPVTAAPLTDAGLTPYHAVRRSLAKLAPGATAL
CCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VIGVGGLGHLGVQVLRAVTAARVIAVDPRSSALSLASKVGADATLTPGPATAAEVRELTH
EEECCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
GVGADVVLDFVGSDDTLALAAQAVRQLGDLTVVGIAGGSLPFSFFGVPYECSVQTTYWGN
CCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCEEEEEEEEECCC
RTELVEVLDLAARGLLTAHTTTFELAQAPEVYAELARGEIDGRAVVVPNRAYRP
HHHHHHHHHHHHHHHEEECCCHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MQALRLRAWKSDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFT
CCCCEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCCCCCCCCCC
LGHENAGWVHTVGTGVTGLEPGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVPSGGG
CCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHCHHHHHCCCCCCCCCCCCC
GLGLDGGMAEYLLVRGARHVVPLPEGLDPVTAAPLTDAGLTPYHAVRRSLAKLAPGATAL
CCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
VIGVGGLGHLGVQVLRAVTAARVIAVDPRSSALSLASKVGADATLTPGPATAAEVRELTH
EEECCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
GVGADVVLDFVGSDDTLALAAQAVRQLGDLTVVGIAGGSLPFSFFGVPYECSVQTTYWGN
CCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCEEEEEEEEECCC
RTELVEVLDLAARGLLTAHTTTFELAQAPEVYAELARGEIDGRAVVVPNRAYRP
HHHHHHHHHHHHHHHEEECCCHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]