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The map label for this gene is ccdA [H]

Identifier: 119716428

GI number: 119716428

Start: 2348173

End: 2349003

Strand: Reverse

Name: ccdA [H]

Synonym: Noca_2199

Alternate gene names: 119716428

Gene position: 2349003-2348173 (Counterclockwise)

Preceding gene: 119716429

Following gene: 119716427

Centisome position: 47.11

GC content: 69.68

Gene sequence:

>831_bases
ATGAACGCCAGCGACCTGGTGATGTCCGGACCGCTCGTGGTCGCCGCACTGTTGGCGATCGCGGCCGGACTGGTGTCCTT
CCTCTCGCCGTGCTGCCTTCCGCTCGTGCCCGGCTACCTGTCATACGTCGCCGGGATGTCCGGCGCGGAGAACCGCCAGC
CCACCGATGCCTGCGCCACCGAAACGACCTTGGAGGGTCCCCGGGCGACGAAGACCGCGGCCCGCACGACCGCCCGCGCG
CCCAGCACACGTCGGGTGGTCCTGGGCGCTGTCCTGTTCGTCGGCGGGTTCGCCGCAGTGTTCACCAGCTACGGAGTCCT
GTTCGGCACCTTCGGTTCCCTGCTGATCGCTCACCAGGAGACGCTGGTCCGCGTCCTGGGGGCGCTCACCATCGTCTTCG
GTCTGATGTTCACCGGCCTGTTCTGGAAACTGCCGATCGCCAGTCGCAGCCTGCGGCTCGGCTACCGCCCGCGCGCCGGG
CTCGCCGGTGCACCACTCCTCGGCGTCATGTTCGGACTCGGCTGGACCCCTTGCATCGGCCCCACTCTCGCCGCCGTGCT
CACCCTTGCCACCAGCAGCGCCGGCGCCGGACGCGGCGCTTTCCTGTCCTTCGCCTACAGCGTCGGCCTGGGGATCCCGT
TCATCATCGCCGCGTTCTCGGTCTCGCGGGCGATGGGCCGGCTCCAATGGGCGCGCCGCCACGCCTCCACGGTGATGCTG
GTCGGAGGGCTGGTCATGGTCACGCTCGGGGTACTCCAGGTCAGCGGGCTGTGGCTGGACCTGATGACGCGCCTCCAAGG
CGTGGTCGCCAACTGGCAGACGCCGATCTGA

Upstream 100 bases:

>100_bases
TGACCCACCCCATCGATCGAGGCCTTTGGCCTAGGTTTCGCACTAGATCCGCCGCGGACAGCGCGGCCCACACAAGGAAA
GGACCGAGACCATCGTTGCC

Downstream 100 bases:

>100_bases
CCATGCCTCCCGGCATTCCTCGCCCGGAGCGGTGGCAAGGAACTGGGTGTCGCGGAATACCCCGGCCGATTTGGTGAAGG
GCACCTGGAGGAAGGTCGCG

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNASDLVMSGPLVVAALLAIAAGLVSFLSPCCLPLVPGYLSYVAGMSGAENRQPTDACATETTLEGPRATKTAARTTARA
PSTRRVVLGAVLFVGGFAAVFTSYGVLFGTFGSLLIAHQETLVRVLGALTIVFGLMFTGLFWKLPIASRSLRLGYRPRAG
LAGAPLLGVMFGLGWTPCIGPTLAAVLTLATSSAGAGRGAFLSFAYSVGLGIPFIIAAFSVSRAMGRLQWARRHASTVML
VGGLVMVTLGVLQVSGLWLDLMTRLQGVVANWQTPI

Sequences:

>Translated_276_residues
MNASDLVMSGPLVVAALLAIAAGLVSFLSPCCLPLVPGYLSYVAGMSGAENRQPTDACATETTLEGPRATKTAARTTARA
PSTRRVVLGAVLFVGGFAAVFTSYGVLFGTFGSLLIAHQETLVRVLGALTIVFGLMFTGLFWKLPIASRSLRLGYRPRAG
LAGAPLLGVMFGLGWTPCIGPTLAAVLTLATSSAGAGRGAFLSFAYSVGLGIPFIIAAFSVSRAMGRLQWARRHASTVML
VGGLVMVTLGVLQVSGLWLDLMTRLQGVVANWQTPI
>Mature_276_residues
MNASDLVMSGPLVVAALLAIAAGLVSFLSPCCLPLVPGYLSYVAGMSGAENRQPTDACATETTLEGPRATKTAARTTARA
PSTRRVVLGAVLFVGGFAAVFTSYGVLFGTFGSLLIAHQETLVRVLGALTIVFGLMFTGLFWKLPIASRSLRLGYRPRAG
LAGAPLLGVMFGLGWTPCIGPTLAAVLTLATSSAGAGRGAFLSFAYSVGLGIPFIIAAFSVSRAMGRLQWARRHASTVML
VGGLVMVTLGVLQVSGLWLDLMTRLQGVVANWQTPI

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 28663; Mature: 28663

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]