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The map label for this gene is pilC [H]

Identifier: 119715365

GI number: 119715365

Start: 1194192

End: 1195427

Strand: Direct

Name: pilC [H]

Synonym: Noca_1127

Alternate gene names: 119715365

Gene position: 1194192-1195427 (Clockwise)

Preceding gene: 119715364

Following gene: 119715366

Centisome position: 23.95

GC content: 67.64

Gene sequence:

>1236_bases
GTGGCAGTAGCCGTGGCCAGCACGACGACGCAGTACGCCTACAAGGTCCGCGACGCCCAGGGCCGGTTCACCGAGGGCAA
GGTGGAGGCCGCCTCGGAGGCGGCTGTCGCCGACAAGCTGCGCGCGATGGGCTACGTCCCGCTCCAGGTGCGGCCCGCCA
ACGTCGGCATGCAGCGCGAGATCAAGCTCGGCTTCAAGAAGCGGATCAAGCCGCGCGACCTCGCGGTCTTCGCCCGCCAG
TTCGCCACCATGATCGACGCCGGCCTGACCATGCTGCGGGCGCTCTCGATCATGGCCGAGCAGGTCGAGAACCCCGAGCT
GCGCAAGGTGCTGCGGGCGGTCAAGCAGGACGTCGAGGCCGGGCACAGCCTGTCGTCGGCCTTCGGCAAGTGGCCGCGCG
TCTTCCCGCCGCTCATGATCAGCATGGCCAAGGCCGGCGAGGCGGGCGGCTTCCTCGACACCGCGATGCGCCAGATCGCC
GACAACTTCGAGGCCGAGGTCAAGCTGCGCAGCAAGATCAAGGCCGCGCTGACCTACCCGACCGTGGTGTTCTTCCTGGC
GATCATCATGTGCATCGCGCTGCTGATCTTCGTGGTCCCGGTCTTCGAGAAGATGTTCAAGGACCTCGGCGGCGAGCTGC
CGCTGCCGACCAAGATCCTGGTGATGCTCTCGGCGGCGATGAAGTACGTCGTACCCCTCGGCGCGGTGCTCACCGGTGCC
CTCGTCTGGTGGTGGCGCCGCTACGGCCGCACCGAGCGGGTCCGCAACGTCGTCGACCCGCTCAAGCTCAAGCTGCCGGT
CTTCGGCAACCTGTTCCGCAAGCTCGCTCTGGCCCGGTTCGCCCGCAACTTCAGCACCCTGCTCTCGGCCGGCGTCCCGA
TCCTCCAGGCGCTCGACATCGTCTCCGACACGACCGGCTCGGTGGTGATCGGCCGCGCCCTGGCCGAGGTCAAGGAGTCG
GTGCGCCAGGGCGAGTCGGTGGCGGGTCCGCTGAGCCACCACGACGTGTTCCCGCCGATGGTCGTGCAGATGATCGCCTC
CGGCGAGGAGTCCGGCGCCATCGACGCGATGCTCGCGAAGATCGCCGAGTTCTACGACGCCGAGGTCGAGTCGATGACCG
AGGGCCTGACCGCCCTGATCGAGCCGCTGATGATCGCGTTCCTCGGCGGCCTCGTCGGGTCGATGATCGTCGCGCTGTAC
ATGCCGATGTTCAAGATCTACGACATGATCGGATGA

Upstream 100 bases:

>100_bases
AGGCCGGCCGGATCACGTACGCCGCGGGCCTCGAGCACAGCTCGAACCGCGCCGACTACGACACGCTCGTCGCCTCCGAC
GTCAAGCGCGCCCCGGCCGG

Downstream 100 bases:

>100_bases
CGGTGCGCGCACAGACCTCCGGAGACACCGTGCGTGCCCTGGTCGAGGGCGGCTGGATCACCCGCGACCAGCTCAGCGAG
GCGGGCCGGCTCGCGGACGA

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAVAVASTTTQYAYKVRDAQGRFTEGKVEAASEAAVADKLRAMGYVPLQVRPANVGMQREIKLGFKKRIKPRDLAVFARQ
FATMIDAGLTMLRALSIMAEQVENPELRKVLRAVKQDVEAGHSLSSAFGKWPRVFPPLMISMAKAGEAGGFLDTAMRQIA
DNFEAEVKLRSKIKAALTYPTVVFFLAIIMCIALLIFVVPVFEKMFKDLGGELPLPTKILVMLSAAMKYVVPLGAVLTGA
LVWWWRRYGRTERVRNVVDPLKLKLPVFGNLFRKLALARFARNFSTLLSAGVPILQALDIVSDTTGSVVIGRALAEVKES
VRQGESVAGPLSHHDVFPPMVVQMIASGEESGAIDAMLAKIAEFYDAEVESMTEGLTALIEPLMIAFLGGLVGSMIVALY
MPMFKIYDMIG

Sequences:

>Translated_411_residues
MAVAVASTTTQYAYKVRDAQGRFTEGKVEAASEAAVADKLRAMGYVPLQVRPANVGMQREIKLGFKKRIKPRDLAVFARQ
FATMIDAGLTMLRALSIMAEQVENPELRKVLRAVKQDVEAGHSLSSAFGKWPRVFPPLMISMAKAGEAGGFLDTAMRQIA
DNFEAEVKLRSKIKAALTYPTVVFFLAIIMCIALLIFVVPVFEKMFKDLGGELPLPTKILVMLSAAMKYVVPLGAVLTGA
LVWWWRRYGRTERVRNVVDPLKLKLPVFGNLFRKLALARFARNFSTLLSAGVPILQALDIVSDTTGSVVIGRALAEVKES
VRQGESVAGPLSHHDVFPPMVVQMIASGEESGAIDAMLAKIAEFYDAEVESMTEGLTALIEPLMIAFLGGLVGSMIVALY
MPMFKIYDMIG
>Mature_410_residues
AVAVASTTTQYAYKVRDAQGRFTEGKVEAASEAAVADKLRAMGYVPLQVRPANVGMQREIKLGFKKRIKPRDLAVFARQF
ATMIDAGLTMLRALSIMAEQVENPELRKVLRAVKQDVEAGHSLSSAFGKWPRVFPPLMISMAKAGEAGGFLDTAMRQIAD
NFEAEVKLRSKIKAALTYPTVVFFLAIIMCIALLIFVVPVFEKMFKDLGGELPLPTKILVMLSAAMKYVVPLGAVLTGAL
VWWWRRYGRTERVRNVVDPLKLKLPVFGNLFRKLALARFARNFSTLLSAGVPILQALDIVSDTTGSVVIGRALAEVKESV
RQGESVAGPLSHHDVFPPMVVQMIASGEESGAIDAMLAKIAEFYDAEVESMTEGLTALIEPLMIAFLGGLVGSMIVALYM
PMFKIYDMIG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=408, Percent_Identity=30.3921568627451, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786295, Length=341, Percent_Identity=29.0322580645161, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44966; Mature: 44835

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAVASTTTQYAYKVRDAQGRFTEGKVEAASEAAVADKLRAMGYVPLQVRPANVGMQRE
CCEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
IKLGFKKRIKPRDLAVFARQFATMIDAGLTMLRALSIMAEQVENPELRKVLRAVKQDVEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GHSLSSAFGKWPRVFPPLMISMAKAGEAGGFLDTAMRQIADNFEAEVKLRSKIKAALTYP
CCHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
TVVFFLAIIMCIALLIFVVPVFEKMFKDLGGELPLPTKILVMLSAAMKYVVPLGAVLTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVWWWRRYGRTERVRNVVDPLKLKLPVFGNLFRKLALARFARNFSTLLSAGVPILQALDI
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VSDTTGSVVIGRALAEVKESVRQGESVAGPLSHHDVFPPMVVQMIASGEESGAIDAMLAK
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
IAEFYDAEVESMTEGLTALIEPLMIAFLGGLVGSMIVALYMPMFKIYDMIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVAVASTTTQYAYKVRDAQGRFTEGKVEAASEAAVADKLRAMGYVPLQVRPANVGMQRE
CEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
IKLGFKKRIKPRDLAVFARQFATMIDAGLTMLRALSIMAEQVENPELRKVLRAVKQDVEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GHSLSSAFGKWPRVFPPLMISMAKAGEAGGFLDTAMRQIADNFEAEVKLRSKIKAALTYP
CCHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
TVVFFLAIIMCIALLIFVVPVFEKMFKDLGGELPLPTKILVMLSAAMKYVVPLGAVLTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVWWWRRYGRTERVRNVVDPLKLKLPVFGNLFRKLALARFARNFSTLLSAGVPILQALDI
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VSDTTGSVVIGRALAEVKESVRQGESVAGPLSHHDVFPPMVVQMIASGEESGAIDAMLAK
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
IAEFYDAEVESMTEGLTALIEPLMIAFLGGLVGSMIVALYMPMFKIYDMIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]