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The map label for this gene is cutS [H]

Identifier: 119714862

GI number: 119714862

Start: 641063

End: 641557

Strand: Reverse

Name: cutS [H]

Synonym: Noca_0606

Alternate gene names: 119714862

Gene position: 641557-641063 (Counterclockwise)

Preceding gene: 119714863

Following gene: 119714861

Centisome position: 12.87

GC content: 62.63

Gene sequence:

>495_bases
ATGAAGACTCGTGTGACCGTAAACGGTGAAGGTTATGAGCGTGACGTCGAGCCACGCATGCTTCTATCGGACTTCTTGCG
GCACGAGCTGGGACTGACCGGCACCAACGTCGGTTGTGAGCACGGGGTGTGCGGCAGCTGCACCGTGCTTCTGGATGGCG
AGCCCGTGCGGTCCTGCACCATGCTTGCGGTGCAATGCGACAGCCGGCGACTGACCACCGTCGAAGGCCTTGCCTGCGAC
GAAAAGCTGCACGGGCTCCAAGATGCATTCTCCGCTTGCCACGGCCTCCAATGCGGCTTCTGCACGCCTGGGATGCTGAT
GACCCTGCTGCCGATTTACAACGAGGCGCGTCGACTCAACGACGACGAAATCCGCGAGGCAATCTCCGGCAATCTGTGTC
GCTGCACTGGGTACCAGCAGATCGTGGAGGCAGCCCGGAAGGCGCTCGGCGAGGCCGCCGACATGGCCGACCCCTGCGTC
GAATCTCGAGCATGA

Upstream 100 bases:

>100_bases
GGACGAAGGAGTATCGGCGCGCTGTCGTCGCGGAGTCACTACGTCGAGCTCTGCGCCAAGCGTTCGATCTGGACCGCGCC
GGAACCGAGAGGAAATCCGC

Downstream 100 bases:

>100_bases
TCGGGCACCGTGACTGGTTGCGGTCCCGGTTGTGCGTGAGTCACAAGTGCGAGCCAAACACTTCGACTCCTTCCGCTCTG
GGCGATGTCCATCGGTCTAA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKTRVTVNGEGYERDVEPRMLLSDFLRHELGLTGTNVGCEHGVCGSCTVLLDGEPVRSCTMLAVQCDSRRLTTVEGLACD
EKLHGLQDAFSACHGLQCGFCTPGMLMTLLPIYNEARRLNDDEIREAISGNLCRCTGYQQIVEAARKALGEAADMADPCV
ESRA

Sequences:

>Translated_164_residues
MKTRVTVNGEGYERDVEPRMLLSDFLRHELGLTGTNVGCEHGVCGSCTVLLDGEPVRSCTMLAVQCDSRRLTTVEGLACD
EKLHGLQDAFSACHGLQCGFCTPGMLMTLLPIYNEARRLNDDEIREAISGNLCRCTGYQQIVEAARKALGEAADMADPCV
ESRA
>Mature_164_residues
MKTRVTVNGEGYERDVEPRMLLSDFLRHELGLTGTNVGCEHGVCGSCTVLLDGEPVRSCTMLAVQCDSRRLTTVEGLACD
EKLHGLQDAFSACHGLQCGFCTPGMLMTLLPIYNEARRLNDDEIREAISGNLCRCTGYQQIVEAARKALGEAADMADPCV
ESRA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=37.5, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI91823271, Length=152, Percent_Identity=36.8421052631579, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=39.1566265060241, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1789232, Length=139, Percent_Identity=43.1654676258993, Blast_Score=110, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=149, Percent_Identity=40.2684563758389, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=149, Percent_Identity=39.5973154362416, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=40.2684563758389, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=34.1935483870968, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=32.9192546583851, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737937, Length=159, Percent_Identity=37.7358490566038, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647199, Length=167, Percent_Identity=31.7365269461078, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=35.4037267080745, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=35.4037267080745, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17845; Mature: 17845

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
7.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
11.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRVTVNGEGYERDVEPRMLLSDFLRHELGLTGTNVGCEHGVCGSCTVLLDGEPVRSCT
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHE
MLAVQCDSRRLTTVEGLACDEKLHGLQDAFSACHGLQCGFCTPGMLMTLLPIYNEARRLN
EEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
DDEIREAISGNLCRCTGYQQIVEAARKALGEAADMADPCVESRA
HHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTRVTVNGEGYERDVEPRMLLSDFLRHELGLTGTNVGCEHGVCGSCTVLLDGEPVRSCT
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHE
MLAVQCDSRRLTTVEGLACDEKLHGLQDAFSACHGLQCGFCTPGMLMTLLPIYNEARRLN
EEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
DDEIREAISGNLCRCTGYQQIVEAARKALGEAADMADPCVESRA
HHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]