| Definition | Paracoccus denitrificans PD1222 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008687 |
| Length | 1,730,097 |
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The map label for this gene is linX [H]
Identifier: 119386292
GI number: 119386292
Start: 734835
End: 735674
Strand: Direct
Name: linX [H]
Synonym: Pden_3583
Alternate gene names: 119386292
Gene position: 734835-735674 (Clockwise)
Preceding gene: 119386289
Following gene: 119386293
Centisome position: 42.47
GC content: 67.74
Gene sequence:
>840_bases ATGGGAGAGACCGGACCTTGGCCATTCACACGGAAAAATGCCGGGCGCGCAAGCCCGACCAAGGAGGAAGACGTGACAGC AAGATTGCAGGGAAAGACCGCCCTGATCACCGGCGGCGCCGGGGGGTGCGGGCTGGCCGCCTCGGAACGCTTTGCCGCCG AGGGCGCAAAGGTGGGCATCGTGGACCTGCCCGGAGCCAAGGGCGAGGAGGTAGCCCGGCGCCTGCGCGAGGCCGGCCAT CAGGCGATCTTCGCGCCTGCCGATGTGTCCGATGCGGGGCAGGTGGCACGGGCCGTCGCCACGGTCGAGGATGCGTTCGG CCCGATCACCGTGCTGATGAACCATGCCGGCATCCTGGCCGCGCTGCCCTTCCTTGAAACCGGCGAAGAGGAATGGGACC GCGTGATGGCGGTGAACGTGAAAAGCATGTTCCTGGTCACGAAGGCCGTGCTGCCCGGCATGATCGCGGCGGGCGGCGGC AGCGTGATCTGCACCTCGTCGATCTCCGCGGTGGTCGGCACGCCGATGGAGGTGCTCTACTGCACCAGCAAGGGCGCCTG CCACATGTTCGCCCGCGCCATCGCCGTCGAGTTTCGGGACCGCGGCATCCGCGCGAACGCGATCTGCCCGGGCTTCATCG CCACCGCCCACGGGCTGCGCGAGATCGAGATGCTGGGCAAGCAGGGCGTCGACGTATCCGAAGGCATGATCGCCCAGGCG CAAGGGCGGCTTTGCAAGCCCGAGGAAGTCGCCGCGGCGGCGCTGTTTCTTGCCAGCGACGACGCCAGCTTCGTCAACGG CGCACATCTGTTCGCGGACAACGGCTACACCGCAATCTGA
Upstream 100 bases:
>100_bases GAACAGACCGGCCAATGCATGCGCCAGGTCACGCCCGATCATATGACTTTCGCCATATGGCGTTTCCGTTCCGTCATCCT AGGCTTCCTCCTATCCGGCC
Downstream 100 bases:
>100_bases AAACAGGGACCGACAGGGATTAACGACATGAACACCTCATCGCACGGCATGACCGTCAACGATTTCGGCCTTGAACATGC GCATTGGCGCAACTGGGTCG
Product: short-chain dehydrogenase/reductase SDR
Products: D-Gluconate; Nicotinamide adenine dinucleotide phosphate [C]
Alternate protein names: 2,5-DDOL dehydrogenase [H]
Number of amino acids: Translated: 279; Mature: 278
Protein sequence:
>279_residues MGETGPWPFTRKNAGRASPTKEEDVTARLQGKTALITGGAGGCGLAASERFAAEGAKVGIVDLPGAKGEEVARRLREAGH QAIFAPADVSDAGQVARAVATVEDAFGPITVLMNHAGILAALPFLETGEEEWDRVMAVNVKSMFLVTKAVLPGMIAAGGG SVICTSSISAVVGTPMEVLYCTSKGACHMFARAIAVEFRDRGIRANAICPGFIATAHGLREIEMLGKQGVDVSEGMIAQA QGRLCKPEEVAAAALFLASDDASFVNGAHLFADNGYTAI
Sequences:
>Translated_279_residues MGETGPWPFTRKNAGRASPTKEEDVTARLQGKTALITGGAGGCGLAASERFAAEGAKVGIVDLPGAKGEEVARRLREAGH QAIFAPADVSDAGQVARAVATVEDAFGPITVLMNHAGILAALPFLETGEEEWDRVMAVNVKSMFLVTKAVLPGMIAAGGG SVICTSSISAVVGTPMEVLYCTSKGACHMFARAIAVEFRDRGIRANAICPGFIATAHGLREIEMLGKQGVDVSEGMIAQA QGRLCKPEEVAAAALFLASDDASFVNGAHLFADNGYTAI >Mature_278_residues GETGPWPFTRKNAGRASPTKEEDVTARLQGKTALITGGAGGCGLAASERFAAEGAKVGIVDLPGAKGEEVARRLREAGHQ AIFAPADVSDAGQVARAVATVEDAFGPITVLMNHAGILAALPFLETGEEEWDRVMAVNVKSMFLVTKAVLPGMIAAGGGS VICTSSISAVVGTPMEVLYCTSKGACHMFARAIAVEFRDRGIRANAICPGFIATAHGLREIEMLGKQGVDVSEGMIAQAQ GRLCKPEEVAAAALFLASDDASFVNGAHLFADNGYTAI
Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=33.8645418326693, Blast_Score=121, Evalue=9e-28, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=36.3636363636364, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI31542939, Length=252, Percent_Identity=30.952380952381, Blast_Score=100, Evalue=3e-21, Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI126723750, Length=243, Percent_Identity=30.8641975308642, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=29.7872340425532, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI310128830, Length=221, Percent_Identity=28.9592760180996, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI310115468, Length=221, Percent_Identity=28.9592760180996, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=36.1809045226131, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=31.4159292035398, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI4504505, Length=239, Percent_Identity=30.5439330543933, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI20149619, Length=237, Percent_Identity=30.8016877637131, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=27.6679841897233, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI142976729, Length=200, Percent_Identity=26.5, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=29.8387096774194, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI83715985, Length=169, Percent_Identity=37.2781065088757, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.1284046692607, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=28.125, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.0578034682081, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032112, Length=188, Percent_Identity=26.063829787234, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=25.6544502617801, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31543615, Length=148, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI25282469, Length=237, Percent_Identity=25.3164556962025, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI157739938, Length=198, Percent_Identity=25.2525252525253, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI302344755, Length=106, Percent_Identity=38.6792452830189, Blast_Score=65, Evalue=1e-10, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=35.546875, Blast_Score=140, Evalue=8e-35, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=35.408560311284, Blast_Score=137, Evalue=1e-33, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=31.4285714285714, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=33.7349397590361, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.710843373494, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=28.2868525896414, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.4, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.3172690763052, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=30.9803921568627, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=25.5555555555556, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786701, Length=196, Percent_Identity=26.0204081632653, Blast_Score=65, Evalue=7e-12, Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=35.3909465020576, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=34.5238095238095, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=31.7829457364341, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=32.6315789473684, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=34.6613545816733, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=31.7647058823529, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=27.3469387755102, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.1044776119403, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=31.1284046692607, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.4436090225564, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=32.8205128205128, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=28.4644194756554, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=29.9625468164794, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI193203117, Length=211, Percent_Identity=25.5924170616114, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=31.6582914572864, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=28.8389513108614, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=27.5132275132275, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=28.6245353159851, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=27.5092936802974, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=27.2251308900524, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=28.1481481481481, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=27.4725274725275, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=35.3535353535354, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=29.0441176470588, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=28.0575539568345, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17536651, Length=272, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=27.2388059701493, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=27.8810408921933, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=29.4776119402985, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=31.1023622047244, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=273, Percent_Identity=25.2747252747253, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=26.7716535433071, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=25.4545454545455, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71982365, Length=215, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17561272, Length=195, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=28.7128712871287, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=32.8185328185328, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=33.8582677165354, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=30.859375, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=31.4176245210728, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.1463414634146, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=29.8039215686275, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=28.740157480315, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI281364892, Length=203, Percent_Identity=32.512315270936, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=32, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI221510726, Length=189, Percent_Identity=35.978835978836, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=35.0393700787402, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24640492, Length=255, Percent_Identity=27.843137254902, Blast_Score=83, Evalue=3e-16, Organism=Drosophila melanogaster, GI21356301, Length=232, Percent_Identity=31.8965517241379, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=5e-15, Organism=Drosophila melanogaster, GI221331218, Length=188, Percent_Identity=30.8510638297872, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI21358495, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI221331216, Length=189, Percent_Identity=31.2169312169312, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24581726, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21355631, Length=180, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=196, Percent_Identity=23.469387755102, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21357673, Length=211, Percent_Identity=29.3838862559242, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24640442, Length=191, Percent_Identity=25.6544502617801, Blast_Score=69, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.69 [C]
Molecular weight: Translated: 28833; Mature: 28702
Theoretical pI: Translated: 5.38; Mature: 5.38
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 5.4 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGETGPWPFTRKNAGRASPTKEEDVTARLQGKTALITGGAGGCGLAASERFAAEGAKVGI CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHCCCCEEEE VDLPGAKGEEVARRLREAGHQAIFAPADVSDAGQVARAVATVEDAFGPITVLMNHAGILA EECCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH ALPFLETGEEEWDRVMAVNVKSMFLVTKAVLPGMIAAGGGSVICTSSISAVVGTPMEVLY HCCCHHCCHHHHHHEEEECHHHHHHHHHHHHCCCEECCCCCEEEECCCHHHHCCCEEEEE CTSKGACHMFARAIAVEFRDRGIRANAICPGFIATAHGLREIEMLGKQGVDVSEGMIAQA ECCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH QGRLCKPEEVAAAALFLASDDASFVNGAHLFADNGYTAI CCCCCCHHHHHHEEEEEECCCCCHHCCEEEEECCCCCCC >Mature Secondary Structure GETGPWPFTRKNAGRASPTKEEDVTARLQGKTALITGGAGGCGLAASERFAAEGAKVGI CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHCCCCEEEE VDLPGAKGEEVARRLREAGHQAIFAPADVSDAGQVARAVATVEDAFGPITVLMNHAGILA EECCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH ALPFLETGEEEWDRVMAVNVKSMFLVTKAVLPGMIAAGGGSVICTSSISAVVGTPMEVLY HCCCHHCCHHHHHHEEEECHHHHHHHHHHHHCCCEECCCCCEEEECCCHHHHCCCEEEEE CTSKGACHMFARAIAVEFRDRGIRANAICPGFIATAHGLREIEMLGKQGVDVSEGMIAQA ECCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH QGRLCKPEEVAAAALFLASDDASFVNGAHLFADNGYTAI CCCCCCHHHHHHEEEEEECCCCCHHCCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+; NADH; NADP+; NADPH [C]
Metal ions: Mn2+ [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.02 {NADP+}} 20 {D-gluconate}} 0.006 {NADPH}} 0.9 {5-keto-D-gluconate}} [C]
Substrates: 5-Dehydro-D-gluconate; H+; Nicotinamide adenine dinucleotide phosphate - reduced [C]
Specific reaction: 5-Dehydro-D-gluconate + H+ + Nicotinamide adenine dinucleotide phosphate - reduced <==> D-Gluconate + Nicotinamide adenine dinucleotide phosphate [C]
General reaction: Redox reaction [C]
Inhibitor: Cd2+; Cs2+; Cu2+; Divalent metal ions; Hg2+; Ni2+; p-Chloromercuribenzoate; Sn2+; Sulfhydryl reagents [C]
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7515041; 12450824 [H]