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The map label for this gene is allB [H]

Identifier: 119386225

GI number: 119386225

Start: 658965

End: 660347

Strand: Direct

Name: allB [H]

Synonym: Pden_3514

Alternate gene names: 119386225

Gene position: 658965-660347 (Clockwise)

Preceding gene: 119386224

Following gene: 119386226

Centisome position: 38.09

GC content: 67.97

Gene sequence:

>1383_bases
ATGGCAGATTTCGATACGGTTTTGACGGGGCGGATCATCCTGACGGATCGCGAGATCGCCCGGGGCTACGTTGCCATTCG
CGATGGCAAGACGGCGCTGGTCGGCGAAGGCGCGGCACCCGCGGGGCGCGAGCGGCATGATTTCGCAAACGGCATCATCC
TGCCCGGCGCGGTCGATGCGCAGGTGCATTCGCTGTCGCAAAGGGGGGCCGAGGGTTTTGCCGCCTCGACCCGCGCTGCT
GCGGCTGGCGGCGTCACTACCATCGTCGACATGCCCTATGACGAGGGCAATCTGGTCTGCTCGGCCGAGGCCGTGGGCCG
CAAGGTCGCGATGATCGACAGCGATGCGCGCGTCGATGTCGCGCTTTACGGCACCATCCGCCCCGAGGAAGGCCCGGCCC
GTATCGCCGAACAGGCGGCGGCGGGCGTTTGCGCCTACAAGTTCTCGACCTTCGGAACCGATCCTCTGCGGTTCCCGCGC
ATCCCGCCGGCGCTGTTGCGTGCCTGCTTTGCCGAGGTCGTGAAGACCGGATTGGCGGCGGGCGTTCACAACGAGGACGA
TGCCTATGTCCGCGCGGCGATCGCCGAGGTCGAGGCCGCGGGCATCACCGACTGGCGCGCGCATGGCCTGTCGCGGCCGG
AACTGGCCGAGACGCTGGCAATGCTGCAGATCTACGAAACCGGCGCCGAAACCGGCTGTCCGGCCCATGTCGTCCATTGC
TCGGTCGGCCGTGGCTACGAGATCGCGGCGATGTATCGCGGCGCCGGCCATCGCTCGACCGTGGAATGCTGCATCCATTA
CCTTGTCCTGGATGAGGAAAACGATGTCGCGCGGCTTGGCGGCAAGGCCAAGATCAACCCGCCCGTCCGTCCCCGCCGCG
AAGTCGAGGCGATCTGGAGGCACCTGGCCGAGGGCCGCGTGTCGATGGTGTCAACCGATCATGTGAGCTGGAGCGAGGAT
CGCAAGACCGATCCCGATATGCTTGGGAACGCCTCCGGCGTGCCGGGGCTCGAGGTGATGGTGCCGCTTTTCGTCAAGGG
CGCGATGGCGCGCGGCGTGCCGCTGGTCTGGGCGGCGCGGCTGATGGCCGAAAATCCGGCCCGGCATTTCCGCCTGGATC
ATCGCAAGGGCGGGCTTCGGGCCGGGCGCGATGCCGACGTGACGGTGCTGGTCGACCGGCCCGCGGTCTATGACGCCGCC
AGCAGCCGCCATTCCATCGCCGGCTGGTCACCCTATCACGGTATGGAACTGCCCTGGACGGTCGCGGCCACCTGGCGGCG
GGGCGAGATGGTCTTTGACGGGACCGAGGTCCTTGCCGTGCCGGGGACCGGCATCTTCGTGCGCCCGCCCGAAACGCTCG
GCCTGCGCGAAGGGTTGCTGTGA

Upstream 100 bases:

>100_bases
AGCCGGCGCATGTCCATGAAATCGCCATAAGGTGTCCTGATTTTGGGATATACCCGAAATCCCGCCAAATCTCGTAGTCG
AAACCTGACTGGAGGAAGGC

Downstream 100 bases:

>100_bases
TGCGGCGCAATCTCGACGCCTCGGCCGAGGCAATCGGCAGGGATATCGATGCGCTGGCCCGGATCACCGATCCCGGGCGC
CCATGGACGCGCCGCGCCTT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MADFDTVLTGRIILTDREIARGYVAIRDGKTALVGEGAAPAGRERHDFANGIILPGAVDAQVHSLSQRGAEGFAASTRAA
AAGGVTTIVDMPYDEGNLVCSAEAVGRKVAMIDSDARVDVALYGTIRPEEGPARIAEQAAAGVCAYKFSTFGTDPLRFPR
IPPALLRACFAEVVKTGLAAGVHNEDDAYVRAAIAEVEAAGITDWRAHGLSRPELAETLAMLQIYETGAETGCPAHVVHC
SVGRGYEIAAMYRGAGHRSTVECCIHYLVLDEENDVARLGGKAKINPPVRPRREVEAIWRHLAEGRVSMVSTDHVSWSED
RKTDPDMLGNASGVPGLEVMVPLFVKGAMARGVPLVWAARLMAENPARHFRLDHRKGGLRAGRDADVTVLVDRPAVYDAA
SSRHSIAGWSPYHGMELPWTVAATWRRGEMVFDGTEVLAVPGTGIFVRPPETLGLREGLL

Sequences:

>Translated_460_residues
MADFDTVLTGRIILTDREIARGYVAIRDGKTALVGEGAAPAGRERHDFANGIILPGAVDAQVHSLSQRGAEGFAASTRAA
AAGGVTTIVDMPYDEGNLVCSAEAVGRKVAMIDSDARVDVALYGTIRPEEGPARIAEQAAAGVCAYKFSTFGTDPLRFPR
IPPALLRACFAEVVKTGLAAGVHNEDDAYVRAAIAEVEAAGITDWRAHGLSRPELAETLAMLQIYETGAETGCPAHVVHC
SVGRGYEIAAMYRGAGHRSTVECCIHYLVLDEENDVARLGGKAKINPPVRPRREVEAIWRHLAEGRVSMVSTDHVSWSED
RKTDPDMLGNASGVPGLEVMVPLFVKGAMARGVPLVWAARLMAENPARHFRLDHRKGGLRAGRDADVTVLVDRPAVYDAA
SSRHSIAGWSPYHGMELPWTVAATWRRGEMVFDGTEVLAVPGTGIFVRPPETLGLREGLL
>Mature_459_residues
ADFDTVLTGRIILTDREIARGYVAIRDGKTALVGEGAAPAGRERHDFANGIILPGAVDAQVHSLSQRGAEGFAASTRAAA
AGGVTTIVDMPYDEGNLVCSAEAVGRKVAMIDSDARVDVALYGTIRPEEGPARIAEQAAAGVCAYKFSTFGTDPLRFPRI
PPALLRACFAEVVKTGLAAGVHNEDDAYVRAAIAEVEAAGITDWRAHGLSRPELAETLAMLQIYETGAETGCPAHVVHCS
VGRGYEIAAMYRGAGHRSTVECCIHYLVLDEENDVARLGGKAKINPPVRPRREVEAIWRHLAEGRVSMVSTDHVSWSEDR
KTDPDMLGNASGVPGLEVMVPLFVKGAMARGVPLVWAARLMAENPARHFRLDHRKGGLRAGRDADVTVLVDRPAVYDAAS
SRHSIAGWSPYHGMELPWTVAATWRRGEMVFDGTEVLAVPGTGIFVRPPETLGLREGLL

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=460, Percent_Identity=24.5652173913043, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI18105007, Length=408, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4503379, Length=461, Percent_Identity=23.644251626898, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4503051, Length=456, Percent_Identity=24.3421052631579, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI62422571, Length=456, Percent_Identity=24.3421052631579, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI190194363, Length=458, Percent_Identity=23.1441048034935, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87082175, Length=460, Percent_Identity=28.9130434782609, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786722, Length=456, Percent_Identity=26.7543859649123, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71989490, Length=464, Percent_Identity=22.8448275862069, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17539558, Length=455, Percent_Identity=23.2967032967033, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322218, Length=421, Percent_Identity=27.3159144893112, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24642586, Length=417, Percent_Identity=26.378896882494, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI221377917, Length=486, Percent_Identity=24.4855967078189, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859883, Length=432, Percent_Identity=26.1574074074074, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49285; Mature: 49153

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFDTVLTGRIILTDREIARGYVAIRDGKTALVGEGAAPAGRERHDFANGIILPGAVDA
CCCCCCEEECEEEEECHHHHCCEEEEECCCEEEEECCCCCCCCCHHHHHCCEEECCCCCH
QVHSLSQRGAEGFAASTRAAAAGGVTTIVDMPYDEGNLVCSAEAVGRKVAMIDSDARVDV
HHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHCCEEEEECCCCEEEE
ALYGTIRPEEGPARIAEQAAAGVCAYKFSTFGTDPLRFPRIPPALLRACFAEVVKTGLAA
EEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVHNEDDAYVRAAIAEVEAAGITDWRAHGLSRPELAETLAMLQIYETGAETGCPAHVVHC
CCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SVGRGYEIAAMYRGAGHRSTVECCIHYLVLDEENDVARLGGKAKINPPVRPRREVEAIWR
ECCCCEEEEEEECCCCCCHHHHHHEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
HLAEGRVSMVSTDHVSWSEDRKTDPDMLGNASGVPGLEVMVPLFVKGAMARGVPLVWAAR
HHHCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LMAENPARHFRLDHRKGGLRAGRDADVTVLVDRPAVYDAASSRHSIAGWSPYHGMELPWT
HHHCCCHHHEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
VAATWRRGEMVFDGTEVLAVPGTGIFVRPPETLGLREGLL
EEEEEECCCEEECCCEEEEECCCEEEEECCHHHCHHCCCC
>Mature Secondary Structure 
ADFDTVLTGRIILTDREIARGYVAIRDGKTALVGEGAAPAGRERHDFANGIILPGAVDA
CCCCCEEECEEEEECHHHHCCEEEEECCCEEEEECCCCCCCCCHHHHHCCEEECCCCCH
QVHSLSQRGAEGFAASTRAAAAGGVTTIVDMPYDEGNLVCSAEAVGRKVAMIDSDARVDV
HHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHCCEEEEECCCCEEEE
ALYGTIRPEEGPARIAEQAAAGVCAYKFSTFGTDPLRFPRIPPALLRACFAEVVKTGLAA
EEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVHNEDDAYVRAAIAEVEAAGITDWRAHGLSRPELAETLAMLQIYETGAETGCPAHVVHC
CCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SVGRGYEIAAMYRGAGHRSTVECCIHYLVLDEENDVARLGGKAKINPPVRPRREVEAIWR
ECCCCEEEEEEECCCCCCHHHHHHEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
HLAEGRVSMVSTDHVSWSEDRKTDPDMLGNASGVPGLEVMVPLFVKGAMARGVPLVWAAR
HHHCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LMAENPARHFRLDHRKGGLRAGRDADVTVLVDRPAVYDAASSRHSIAGWSPYHGMELPWT
HHHCCCHHHEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
VAATWRRGEMVFDGTEVLAVPGTGIFVRPPETLGLREGLL
EEEEEECCCEEECCCEEEEECCCEEEEECCHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA