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The map label for this gene is ycgM [C]

Identifier: 119386149

GI number: 119386149

Start: 579311

End: 579997

Strand: Direct

Name: ycgM [C]

Synonym: Pden_3437

Alternate gene names: 119386149

Gene position: 579311-579997 (Clockwise)

Preceding gene: 119386148

Following gene: 119386152

Centisome position: 33.48

GC content: 67.98

Gene sequence:

>687_bases
ATGACCCATGTTCTTCCCTTGCCCGCCATCCCCTCGGTTCCCGTCGCCGGCAGCGACGACCGCTTTCCGGTGCGCCGGAT
CTTTTGCGTCGGGCGCAACTATGCCGATCATGCCCGCGAAATGGGCCACGACCCGGATCGCGAACCGCCGTTCTTCTTTT
CGAAGCCTGCGGACGCGCTGCTGACGGACGATGCGCCCTTGCCCTATCCGCCCAGGACCGCAGACCTGCATTACGAAGGC
GAGTTGGTGGTGGCGATCGGCAAGGCAGGCCGCGACATTCCCATGACCGAGGCGGCACGGCATGTCTGGGGCTATGCGGC
CGGCAACGATTTCACCCGCCGCGATCTTCAGGCCGAGGCGAAGAAACTGGGCCGGCCCTGGGACATGGCCAAGGGCTTTG
ACCATTCGGCGGCCTGCGGGGCGATCACGCCCGCGGCGCAAGCGGGACCGATGGATCGCGGCCGGATCATGTCGACGGTG
GACGGTGTCGTCCGGCAGGACGGCGACCTGGGGCAGATGATCTGGTCGATCCCCGAGATCGTGGCGATCCTGTCGGGCTA
TGTCGGCCTGGCGGCGGGCGACCTGATCTTTACGGGCACTCCGGCGGGCGTCGGCGCGCTGTCCCGCGGTGCACGGGTGG
CCGTGCGGATCGACGGCCTGGCGCCGCTGGTGACGGACATCGTCTAG

Upstream 100 bases:

>100_bases
CTTCCGAGACCGTGATCGTGACCCGATCCGGCATCGAGATCCTTTCCGACCTGCCGCGCACCCTTTGCATCCGTTGAGAT
TTCTGACAGGAGCGACGCCC

Downstream 100 bases:

>100_bases
ACCTGTCTCGGCCCTTCGATCGCGGGTTCTGGTGAGGCCCGTTTTCGATCCGTGCCGGGGGCCATGGTCCTTTTCGAGAC
CATGACCCCCGAACGCGGAA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTHVLPLPAIPSVPVAGSDDRFPVRRIFCVGRNYADHAREMGHDPDREPPFFFSKPADALLTDDAPLPYPPRTADLHYEG
ELVVAIGKAGRDIPMTEAARHVWGYAAGNDFTRRDLQAEAKKLGRPWDMAKGFDHSAACGAITPAAQAGPMDRGRIMSTV
DGVVRQDGDLGQMIWSIPEIVAILSGYVGLAAGDLIFTGTPAGVGALSRGARVAVRIDGLAPLVTDIV

Sequences:

>Translated_228_residues
MTHVLPLPAIPSVPVAGSDDRFPVRRIFCVGRNYADHAREMGHDPDREPPFFFSKPADALLTDDAPLPYPPRTADLHYEG
ELVVAIGKAGRDIPMTEAARHVWGYAAGNDFTRRDLQAEAKKLGRPWDMAKGFDHSAACGAITPAAQAGPMDRGRIMSTV
DGVVRQDGDLGQMIWSIPEIVAILSGYVGLAAGDLIFTGTPAGVGALSRGARVAVRIDGLAPLVTDIV
>Mature_227_residues
THVLPLPAIPSVPVAGSDDRFPVRRIFCVGRNYADHAREMGHDPDREPPFFFSKPADALLTDDAPLPYPPRTADLHYEGE
LVVAIGKAGRDIPMTEAARHVWGYAAGNDFTRRDLQAEAKKLGRPWDMAKGFDHSAACGAITPAAQAGPMDRGRIMSTVD
GVVRQDGDLGQMIWSIPEIVAILSGYVGLAAGDLIFTGTPAGVGALSRGARVAVRIDGLAPLVTDIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=39.4088669950739, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=40.8163265306122, Blast_Score=147, Evalue=5e-36,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=40.8163265306122, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI156231349, Length=212, Percent_Identity=33.0188679245283, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI40786394, Length=212, Percent_Identity=32.0754716981132, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=38.6934673366834, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=185, Percent_Identity=35.6756756756757, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=32.8888888888889, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572127, Length=211, Percent_Identity=32.7014218009479, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571789, Length=211, Percent_Identity=31.7535545023697, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24320; Mature: 24189

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVLPLPAIPSVPVAGSDDRFPVRRIFCVGRNYADHAREMGHDPDREPPFFFSKPADAL
CCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHCCCCCCCCCCEEECCCCCCE
LTDDAPLPYPPRTADLHYEGELVVAIGKAGRDIPMTEAARHVWGYAAGNDFTRRDLQAEA
EECCCCCCCCCCCCCEEECCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
KKLGRPWDMAKGFDHSAACGAITPAAQAGPMDRGRIMSTVDGVVRQDGDLGQMIWSIPEI
HHCCCCHHHHCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
VAILSGYVGLAAGDLIFTGTPAGVGALSRGARVAVRIDGLAPLVTDIV
HHHHHHHHHHEECCEEEECCCCCHHHHCCCCEEEEEECCCHHHHHHCC
>Mature Secondary Structure 
THVLPLPAIPSVPVAGSDDRFPVRRIFCVGRNYADHAREMGHDPDREPPFFFSKPADAL
CCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHCCCCCCCCCCEEECCCCCCE
LTDDAPLPYPPRTADLHYEGELVVAIGKAGRDIPMTEAARHVWGYAAGNDFTRRDLQAEA
EECCCCCCCCCCCCCEEECCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
KKLGRPWDMAKGFDHSAACGAITPAAQAGPMDRGRIMSTVDGVVRQDGDLGQMIWSIPEI
HHCCCCHHHHCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
VAILSGYVGLAAGDLIFTGTPAGVGALSRGARVAVRIDGLAPLVTDIV
HHHHHHHHHHEECCEEEECCCCCHHHHCCCCEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]