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The map label for this gene is atoC [H]

Identifier: 118578876

GI number: 118578876

Start: 456909

End: 457283

Strand: Direct

Name: atoC [H]

Synonym: Ppro_0435

Alternate gene names: 118578876

Gene position: 456909-457283 (Clockwise)

Preceding gene: 118578875

Following gene: 118578877

Centisome position: 11.4

GC content: 51.73

Gene sequence:

>375_bases
GTGGCAGAACAGAAGAAACGCATACTGGTCGTTGATGATGAGGAAAACGCCCGTATTGCCTTGTCGAAGATTCTTACCCG
GGAGGGGTACGAAGTGGCATCAGCTGGCAACGGCCAGGAGGCGCTTACCTATCTGCGCGCCAGGGACGTGGAACTGGTCA
TCACCGATATCAACATGCCGGAGATGAACGGCATGGCATTTCTGCGCGAACTGAACAAGATCCGTCCTGCCAGCAATGTC
ATCATGATCACCGCTTACGGCGAGGTTGAATCCTATATCGAGGCCATGAATCTGGGCGCCTTTGAATACATTAACAAGCC
GGTCAAGATCGATGAGCTTAAAAGAATCATCGCCAAGGTTTTCAAGAAGGGCTGA

Upstream 100 bases:

>100_bases
AATCATACGTGTTAAGATCTGTAAAAATTGGCGGGTGGTCTTGACAGCTGCCGGCCAGGTGCTAGACTCGTATCCATAGT
CTAATGTGGGGGAGTGCGTC

Downstream 100 bases:

>100_bases
TTGTTTTCACAAGGAGGTGCATGATGAAACCGTTCGAACGGATCTTGATCGCCATCGATTTTTCGGAGAATTCCACCTAT
GCCTTTGACTGCGCCCTGAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAEQKKRILVVDDEENARIALSKILTREGYEVASAGNGQEALTYLRARDVELVITDINMPEMNGMAFLRELNKIRPASNV
IMITAYGEVESYIEAMNLGAFEYINKPVKIDELKRIIAKVFKKG

Sequences:

>Translated_124_residues
MAEQKKRILVVDDEENARIALSKILTREGYEVASAGNGQEALTYLRARDVELVITDINMPEMNGMAFLRELNKIRPASNV
IMITAYGEVESYIEAMNLGAFEYINKPVKIDELKRIIAKVFKKG
>Mature_123_residues
AEQKKRILVVDDEENARIALSKILTREGYEVASAGNGQEALTYLRARDVELVITDINMPEMNGMAFLRELNKIRPASNVI
MITAYGEVESYIEAMNLGAFEYINKPVKIDELKRIIAKVFKKG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=41.3793103448276, Blast_Score=100, Evalue=3e-23,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=39.4736842105263, Blast_Score=90, Evalue=5e-20,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=37.6068376068376, Blast_Score=86, Evalue=6e-19,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.8965517241379, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=31.404958677686, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=39.8230088495575, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=126, Percent_Identity=34.1269841269841, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1787229, Length=108, Percent_Identity=29.6296296296296, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1786911, Length=107, Percent_Identity=33.6448598130841, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI145693157, Length=110, Percent_Identity=30.9090909090909, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 14009; Mature: 13877

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQKKRILVVDDEENARIALSKILTREGYEVASAGNGQEALTYLRARDVELVITDINMP
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCEEEEEEECCCC
EMNGMAFLRELNKIRPASNVIMITAYGEVESYIEAMNLGAFEYINKPVKIDELKRIIAKV
CCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
FKKG
HCCC
>Mature Secondary Structure 
AEQKKRILVVDDEENARIALSKILTREGYEVASAGNGQEALTYLRARDVELVITDINMP
CCCCCCEEEEECCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCEEEEEEECCCC
EMNGMAFLRELNKIRPASNVIMITAYGEVESYIEAMNLGAFEYINKPVKIDELKRIIAKV
CCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
FKKG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]