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The map label for this gene is mtnP [H]

Identifier: 118578872

GI number: 118578872

Start: 453145

End: 454008

Strand: Direct

Name: mtnP [H]

Synonym: Ppro_0431

Alternate gene names: 118578872

Gene position: 453145-454008 (Clockwise)

Preceding gene: 118578870

Following gene: 118578873

Centisome position: 11.31

GC content: 63.43

Gene sequence:

>864_bases
ATGGCTATGGATGCGGTCGGCGTCATCGGAGGGAGCGGGCTGTACGAGATGGAAGGGCTTGAGGATGTGGCGCGGGTCAG
GCTGGAGACCCCCTTTGGCGCCCCCTCCGACGAATATGTGACCGGTATGCTGGGCGGTGTGCCCATGGTGTTTCTGCCGC
GCCATGGTCGCGGACACCGTCTGCTCCCCTCGGAAGTCAACTATTGCGCCAACATCCATGGCATGAAGCAGCTGGGGGTG
GGACGGATCATCTCGGTTTCTGCCGTGGGCAGCCTGAAGGAATCCATCGAACCGGGGCACATCGTTATTCCGGACCAGTT
CGTTGATCGCACCAAGGGGGTGCGCCGGGACAGCTTTTTCGGCGACGGGTTGGTGGCTCATGCCGGTTTTGCCGATCCGG
TCTGCCACGAGCTCTCGGTCCTGCTGTACCGGGCGGCGCTCACCGCCGGCGCCACCGTCCACAGGGGCGGGACCTACGTC
TGCATGGAGGGGCCGGCCTTCTCCACCCGTGCCGAGTCGTTCATGTATCGCTCCCTTGATGCGTCGGTGATCGGCATGAC
CAACCTGACCGAAGCCAAGCTGGCCAGGGAGGCCGAGATCTGCTACGGCATCATCGCCCTGTCCACCGATTACGACTGCT
GGCACGAGACCCACGACGACGTGACGGTGGAGGCGATCCTGGAGATCATTCGCCGCAACGTGGCCATGGCCAAGAGCATC
ATCCGTCAGGCCGTGACGGAGATCCGCGCCGTGAGGAACTGTGCCTGCGCAACCGCCATGCAGTACGCCGTACTGACCGA
CAGAAGCGTCATACCGGCGGAGACGAGGCGCAAGCTTGACCTGATCGTCGGCAAGTATCTGTAG

Upstream 100 bases:

>100_bases
GTGCTTTGTGCCCGAAACCCGTAAAGTTCGAGGCGGTTTATGCCGCTCTTCTCCATTGCGGAGCGGACTTATGGCTGTAT
GACGAAAGGAAATCATAGGT

Downstream 100 bases:

>100_bases
TACCTAATCACCTGACAGGAGAGGAGTATTCATGGGCATCGTTGTCGTCGGTACCGTGGCTTTTGACACGGTGGAAACCC
CCTTTGGCAGGGGAGAGCAT

Product: methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAMDAVGVIGGSGLYEMEGLEDVARVRLETPFGAPSDEYVTGMLGGVPMVFLPRHGRGHRLLPSEVNYCANIHGMKQLGV
GRIISVSAVGSLKESIEPGHIVIPDQFVDRTKGVRRDSFFGDGLVAHAGFADPVCHELSVLLYRAALTAGATVHRGGTYV
CMEGPAFSTRAESFMYRSLDASVIGMTNLTEAKLAREAEICYGIIALSTDYDCWHETHDDVTVEAILEIIRRNVAMAKSI
IRQAVTEIRAVRNCACATAMQYAVLTDRSVIPAETRRKLDLIVGKYL

Sequences:

>Translated_287_residues
MAMDAVGVIGGSGLYEMEGLEDVARVRLETPFGAPSDEYVTGMLGGVPMVFLPRHGRGHRLLPSEVNYCANIHGMKQLGV
GRIISVSAVGSLKESIEPGHIVIPDQFVDRTKGVRRDSFFGDGLVAHAGFADPVCHELSVLLYRAALTAGATVHRGGTYV
CMEGPAFSTRAESFMYRSLDASVIGMTNLTEAKLAREAEICYGIIALSTDYDCWHETHDDVTVEAILEIIRRNVAMAKSI
IRQAVTEIRAVRNCACATAMQYAVLTDRSVIPAETRRKLDLIVGKYL
>Mature_286_residues
AMDAVGVIGGSGLYEMEGLEDVARVRLETPFGAPSDEYVTGMLGGVPMVFLPRHGRGHRLLPSEVNYCANIHGMKQLGVG
RIISVSAVGSLKESIEPGHIVIPDQFVDRTKGVRRDSFFGDGLVAHAGFADPVCHELSVLLYRAALTAGATVHRGGTYVC
MEGPAFSTRAESFMYRSLDASVIGMTNLTEAKLAREAEICYGIIALSTDYDCWHETHDDVTVEAILEIIRRNVAMAKSII
RQAVTEIRAVRNCACATAMQYAVLTDRSVIPAETRRKLDLIVGKYL

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=249, Percent_Identity=44.9799196787149, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI71980569, Length=255, Percent_Identity=43.1372549019608, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323045, Length=302, Percent_Identity=35.7615894039735, Blast_Score=178, Evalue=7e-46,
Organism=Drosophila melanogaster, GI20130079, Length=274, Percent_Identity=37.5912408759124, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI221459247, Length=256, Percent_Identity=32.8125, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31192; Mature: 31061

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMDAVGVIGGSGLYEMEGLEDVARVRLETPFGAPSDEYVTGMLGGVPMVFLPRHGRGHR
CCCCCEEEECCCCCCHHCCHHHHHHEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCC
LLPSEVNYCANIHGMKQLGVGRIISVSAVGSLKESIEPGHIVIPDQFVDRTKGVRRDSFF
CCHHHHHHHHCCCCHHHHCCCCEEEHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCCCCC
GDGLVAHAGFADPVCHELSVLLYRAALTAGATVHRGGTYVCMEGPAFSTRAESFMYRSLD
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCHHHHHHHHHHCC
ASVIGMTNLTEAKLAREAEICYGIIALSTDYDCWHETHDDVTVEAILEIIRRNVAMAKSI
CCEECCCCCHHHHHHHHHHHHEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IRQAVTEIRAVRNCACATAMQYAVLTDRSVIPAETRRKLDLIVGKYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AMDAVGVIGGSGLYEMEGLEDVARVRLETPFGAPSDEYVTGMLGGVPMVFLPRHGRGHR
CCCCEEEECCCCCCHHCCHHHHHHEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCC
LLPSEVNYCANIHGMKQLGVGRIISVSAVGSLKESIEPGHIVIPDQFVDRTKGVRRDSFF
CCHHHHHHHHCCCCHHHHCCCCEEEHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCCCCC
GDGLVAHAGFADPVCHELSVLLYRAALTAGATVHRGGTYVCMEGPAFSTRAESFMYRSLD
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCHHHHHHHHHHCC
ASVIGMTNLTEAKLAREAEICYGIIALSTDYDCWHETHDDVTVEAILEIIRRNVAMAKSI
CCEECCCCCHHHHHHHHHHHHEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IRQAVTEIRAVRNCACATAMQYAVLTDRSVIPAETRRKLDLIVGKYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA