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The map label for this gene is ymdB [C]

Identifier: 118578750

GI number: 118578750

Start: 305804

End: 306325

Strand: Direct

Name: ymdB [C]

Synonym: Ppro_0308

Alternate gene names: 118578750

Gene position: 305804-306325 (Clockwise)

Preceding gene: 118578749

Following gene: 118578751

Centisome position: 7.63

GC content: 66.28

Gene sequence:

>522_bases
ATGACAACCATCGAGATCATTCAGACCGATATCACCACCCTGGCGGTGGATGCCATCGTCAATGCGGCTAACAGCACCCT
GCTGGGGGGGGGAGGGGTTGACGGCGCCATCCACCGTGCAGCCGGTCCGGATCTGGTGCAGGAGTGCGCCACTCTGGGGG
GCTGTCCCACCGGTGAGGCCAAGATCACCAAGGGGTACCTGCTCCCGGCCCGGCATGTCATCCACACGGTCGGCCCGGTC
TGGCACGGCGGAGGGAAGGGAGAGCCGAAACTCCTGGAGAGCGCCTACCGCACCTGCTTCCGGGTGGCCCGCCAGCACAA
CCTGGCCAGCATCGCCTTCCCGGCCATCAGCGCCGGCATCTACGGCTATCCCATGGCCGACGCCGCCATGATCGCCCTCA
CCGTGGCCAGGGAGGAGGCGGAAAAGGGAGGTCTGCAGCGGATCATCTTCGTCCCCTTCAGCAGCCAGGCGGAGAAGGTC
TACCGGGATGTTGCCGCCAGTTTGGGGATCCAGCCCGCGTAG

Upstream 100 bases:

>100_bases
TGATCCCCACGAATAGCAGCCGCTGGTGGTTGCAAGCGCGGCGAAACCTGCTATCACAGGTGATGCTTGCCAGTGCCAAT
CAACGCGAGGGGGAGTTCCT

Downstream 100 bases:

>100_bases
TCCCGCCGTTACCCATCCGTGGGGGAGGGCGCACCCTCCCCCGTCTTCACTCCGTCCCTCTTTTTCGTACTCACCTGTAA
ACATTAGAACGTTTGACATC

Product: appr-1-p processing domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTTIEIIQTDITTLAVDAIVNAANSTLLGGGGVDGAIHRAAGPDLVQECATLGGCPTGEAKITKGYLLPARHVIHTVGPV
WHGGGKGEPKLLESAYRTCFRVARQHNLASIAFPAISAGIYGYPMADAAMIALTVAREEAEKGGLQRIIFVPFSSQAEKV
YRDVAASLGIQPA

Sequences:

>Translated_173_residues
MTTIEIIQTDITTLAVDAIVNAANSTLLGGGGVDGAIHRAAGPDLVQECATLGGCPTGEAKITKGYLLPARHVIHTVGPV
WHGGGKGEPKLLESAYRTCFRVARQHNLASIAFPAISAGIYGYPMADAAMIALTVAREEAEKGGLQRIIFVPFSSQAEKV
YRDVAASLGIQPA
>Mature_172_residues
TTIEIIQTDITTLAVDAIVNAANSTLLGGGGVDGAIHRAAGPDLVQECATLGGCPTGEAKITKGYLLPARHVIHTVGPVW
HGGGKGEPKLLESAYRTCFRVARQHNLASIAFPAISAGIYGYPMADAAMIALTVAREEAEKGGLQRIIFVPFSSQAEKVY
RDVAASLGIQPA

Specific function: Unknown

COG id: COG2110

COG function: function code R; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Macro domain [H]

Homologues:

Organism=Homo sapiens, GI13569840, Length=162, Percent_Identity=52.4691358024691, Blast_Score=163, Evalue=8e-41,
Organism=Homo sapiens, GI117968621, Length=162, Percent_Identity=51.8518518518518, Blast_Score=160, Evalue=5e-40,
Organism=Homo sapiens, GI207450721, Length=144, Percent_Identity=38.1944444444444, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI8923143, Length=144, Percent_Identity=38.1944444444444, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI154813199, Length=172, Percent_Identity=33.1395348837209, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI20336746, Length=172, Percent_Identity=30.8139534883721, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI226371718, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371716, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371714, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371712, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371710, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371706, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI93141018, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI93141020, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4758496, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1787283, Length=173, Percent_Identity=48.5549132947977, Blast_Score=158, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17538214, Length=172, Percent_Identity=45.9302325581395, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24586353, Length=149, Percent_Identity=38.255033557047, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002589
- InterPro:   IPR022942 [H]

Pfam domain/function: PF01661 Macro [H]

EC number: NA

Molecular weight: Translated: 18024; Mature: 17893

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS51154 MACRO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIEIIQTDITTLAVDAIVNAANSTLLGGGGVDGAIHRAAGPDLVQECATLGGCPTGEA
CCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCC
KITKGYLLPARHVIHTVGPVWHGGGKGEPKLLESAYRTCFRVARQHNLASIAFPAISAGI
EECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
YGYPMADAAMIALTVAREEAEKGGLQRIIFVPFSSQAEKVYRDVAASLGIQPA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTIEIIQTDITTLAVDAIVNAANSTLLGGGGVDGAIHRAAGPDLVQECATLGGCPTGEA
CCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCC
KITKGYLLPARHVIHTVGPVWHGGGKGEPKLLESAYRTCFRVARQHNLASIAFPAISAGI
EECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
YGYPMADAAMIALTVAREEAEKGGLQRIIFVPFSSQAEKVYRDVAASLGIQPA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]