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The map label for this gene is speD [H]

Identifier: 118480248

GI number: 118480248

Start: 4951627

End: 4951998

Strand: Direct

Name: speD [H]

Synonym: BALH_4706

Alternate gene names: 118480248

Gene position: 4951627-4951998 (Clockwise)

Preceding gene: 118480247

Following gene: 118480253

Centisome position: 94.19

GC content: 35.48

Gene sequence:

>372_bases
ATGGAATATTCTACTTTCGGTAAGCATATAATAGTAGATTTGTGGGGAGTGGATTTTTCCCTATTAGATGATATGTACTT
TTTAGAACATCATTTAGTTCACGCTGCCGCTCTCTCTGGTGCCCATGTTTTAAACGTAAGTACAAAAGAATTTCATCCGC
ATGGCGTTACTGTTTTAGTTTTACTATCAGAAAGTCACCTTTCTATTCACACTTATCCAGAAAAAAACTTTGCAGCCATT
GACTGTTATACGTGCGGTACGACCGTTGAACCGCAAATAGCGATTGATTATATCGTAAGTATATTGGAACCAAATGAGAT
GCATATAAAAAGATTAATTCGTGGTATAGGAGAGATTGTAAATACTGATTAA

Upstream 100 bases:

>100_bases
TAATTTCGCTCTTCTAAACTCAGAATCGAACCTTATCCTACACCAATGTTACAAAAAGGAAATGGAGTTTTGACGATATC
ACAGGAAGGAGTGCTACCTT

Downstream 100 bases:

>100_bases
ATATCACTCTTACTCATTTGTAAAAAGGAGGAGTGTAAATACCATCAGTGGAACAAACATTCCACTGATGGTACAGACAC
ATACATATTTTTTCACCTTA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC 2; SAMDC 2 [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLVHAAALSGAHVLNVSTKEFHPHGVTVLVLLSESHLSIHTYPEKNFAAI
DCYTCGTTVEPQIAIDYIVSILEPNEMHIKRLIRGIGEIVNTD

Sequences:

>Translated_123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLVHAAALSGAHVLNVSTKEFHPHGVTVLVLLSESHLSIHTYPEKNFAAI
DCYTCGTTVEPQIAIDYIVSILEPNEMHIKRLIRGIGEIVNTD
>Mature_123_residues
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLVHAAALSGAHVLNVSTKEFHPHGVTVLVLLSESHLSIHTYPEKNFAAI
DCYTCGTTVEPQIAIDYIVSILEPNEMHIKRLIRGIGEIVNTD

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13815; Mature: 13815

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLVHAAALSGAHVLNVSTKEFHPHGVTVLV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEE
LLSESHLSIHTYPEKNFAAIDCYTCGTTVEPQIAIDYIVSILEPNEMHIKRLIRGIGEIV
EEECCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NTD
CCC
>Mature Secondary Structure
MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLVHAAALSGAHVLNVSTKEFHPHGVTVLV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEE
LLSESHLSIHTYPEKNFAAIDCYTCGTTVEPQIAIDYIVSILEPNEMHIKRLIRGIGEIV
EEECCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NTD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]