Click here to switch to the map view.

The map label for this gene is pcaD [C]

Identifier: 118478587

GI number: 118478587

Start: 3150573

End: 3151490

Strand: Reverse

Name: pcaD [C]

Synonym: BALH_2964

Alternate gene names: 118478587

Gene position: 3151490-3150573 (Counterclockwise)

Preceding gene: 118478591

Following gene: 118478586

Centisome position: 59.95

GC content: 36.49

Gene sequence:

>918_bases
ATGGGGGAACTTGTGATGATTAAGCCTGCAACAATGGAGTTTGTTTCACTATCAAACGGAGAAACGATTGCGTATCAGGA
AGTTGGAAGGCAAAATGCAGAAATTCTTGTACTCATTCACGGAAACATGACATCGTCACAACATTGGGATTTAGTTATTG
AAAAGCTGCAAGATCAATACCATATTTACGCTCTGGATTTAAGAGGATTTGGTCAATCAACATATAATAAACCGATAGAT
TCAATACAAGACTTTGCAGAAGATGTAAAACTATTTATCGACGGGTTAAAACTAGAGAAATTTTCATTAATGGGCTGGTC
AATGGGCGGTGGTGTTGCGATGCAATTTACAGCGAATCATCCAACGTTTGTCGAAAAGTTAATTTTAGTAGAATCAGTAG
GAATGAAGGGATATCCAATCTTTAAAAAAGATATAAATGGGCAGCCGATTGTATCTAGTTTAGTTAAGACGAAAGAAGAA
ATTGCGCAAGATCCTGTTCAAATTGCACCAGTGTTAGATGCGATAAAAAATATGAATAAACTATATTATCGTACAGTATG
GAATTTGTTAATATATACACATAATCAACCTGAACCGGATCGCTATGAAAAGTATTTAGACGATATGTTAACGCAGCGTA
ATTTCGTAGATGTGAATTATGCGCTCATTACATTTAATATTTCGGATGAACATAACGGGGTTGTAGAGGGAAATAAGCAA
ATTCATCGTATTAAAGCTCCGACACTCGTCATACAAGGCGACAGAGATTATGTCGTACCGCAAGTAGTGGGTGAGGAGTT
AGCAAAACATTTGCCGAATGCAGAGTTGAAGATATTAGAAGATTGCGGACACTCACCGTTTATAGATTGCTTAGATGTAT
TTATTAAGTATGTAGAGGATTGGTTAGAAGGTAAGTAG

Upstream 100 bases:

>100_bases
GTTGATTTATGTAAAAATTTCGTATTGGTTTTATGTTGCGAACGTACATTCTGCATGCTATTCTTTAAGTAAGTAAAGAA
TTTTCTTTCTATTAAAAAGA

Downstream 100 bases:

>100_bases
GTTGGGGAAGAAGTTAGATGACATGTGTCTAGCTTCTTTTTTGTGGAAAAATGAAAATTATTTCATCCACTAGTTCTTTC
TTATTACATAGTAAACAATA

Product: 3-oxoadipate enol-lactonase

Products: 3-oxoadipate

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MGELVMIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNKPID
SIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEE
IAQDPVQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQ
IHRIKAPTLVIQGDRDYVVPQVVGEELAKHLPNAELKILEDCGHSPFIDCLDVFIKYVEDWLEGK

Sequences:

>Translated_305_residues
MGELVMIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNKPID
SIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEE
IAQDPVQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQ
IHRIKAPTLVIQGDRDYVVPQVVGEELAKHLPNAELKILEDCGHSPFIDCLDVFIKYVEDWLEGK
>Mature_304_residues
GELVMIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNKPIDS
IQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEI
AQDPVQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQI
HRIKAPTLVIQGDRDYVVPQVVGEELAKHLPNAELKILEDCGHSPFIDCLDVFIKYVEDWLEGK

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=123, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI13376164, Length=123, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081721, Length=306, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.1.24

Molecular weight: Translated: 34753; Mature: 34622

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGELVMIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHWDLVIEKLQDQY
CCCEEEEECCCEEEEECCCCCEEEHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCE
HIYALDLRGFGQSTYNKPIDSIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANH
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCEEEEEECCC
PTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNK
HHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQ
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCEECCCCE
IHRIKAPTLVIQGDRDYVVPQVVGEELAKHLPNAELKILEDCGHSPFIDCLDVFIKYVED
EEEEECCEEEEECCCCEECHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHH
WLEGK
HHCCC
>Mature Secondary Structure 
GELVMIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHWDLVIEKLQDQY
CCEEEEECCCEEEEECCCCCEEEHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCE
HIYALDLRGFGQSTYNKPIDSIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANH
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCEEEEEECCC
PTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNK
HHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQ
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCEECCCCE
IHRIKAPTLVIQGDRDYVVPQVVGEELAKHLPNAELKILEDCGHSPFIDCLDVFIKYVED
EEEEECCEEEEECCCCEECHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHH
WLEGK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxoadipate enol-lactone; H2O

Specific reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]