Click here to switch to the map view.

The map label for this gene is 118478186

Identifier: 118478186

GI number: 118478186

Start: 2704765

End: 2705802

Strand: Reverse

Name: 118478186

Synonym: BALH_2543

Alternate gene names: NA

Gene position: 2705802-2704765 (Counterclockwise)

Preceding gene: 118478187

Following gene: 118478185

Centisome position: 51.47

GC content: 38.63

Gene sequence:

>1038_bases
ATGAGGACACAAAAAGTCTTTACGACGATTGATACACATACGGGTGGGAATCCAACGAGAACATTGATTAGCGGACTACC
TAAGTTACTTGGAGAGACGATGGCAGAGAAAATGTTACATATGAAAAAGGAGTATGACTGGATTCGCAAATTGTTAATGA
ATGAACCGCGTGGTCATGATGTAATGTCCGGAGCACTATTAACAGATCCATGTCACCCTGATGCCGATATTGGTGTTATA
TACATAGAGACAGGCGGATATTTACCAATGTGTGGTCACGATACAATTGGTGTATGTACAGCTTTAATTGAATCAGGTTT
AATTCCGGTAGTTGAACCGATTACTTCGTTAAAGTTAGATACGCCAGCTGGCTTAGTTGAAGTGGATATCTTTGTTCGAG
ATGGAAAAGCGAAAGAAGTCTCCTTTTGTAACATACCAGCTTTTGTACTGAAACATATCACGGTAGACGTCGAGAACATT
GGAACTGTAGAGGCTGATATTGCGTATGGAGGGAACTTTTATGCCATTATCGATGCGAAATCAGTAGGGTTAGAGTTAGT
ACCGGAACGTGCATCTACAATTATCGATAAGGCAATTCATATTAGAAATATCATTAATGAGAGATTTGAAATCATTCATC
CAGAGTATTCGTTTATTAGAGGATTAACCCATGTGGAGTTTTATACAGATCCTACTCATGAAAGTGCACATGTAAAAAAC
ACAGTTGTCGTTCCGCCTGGAGGAATTGATCGATCTCCATGTGGTACAGGAACATCAGCGAAGTTAGCTGTATTATACGC
AAACCAAAAAATTGAAATGAATGAAGAGTTTGTTCATGAGAGTATTGTTGGTTCTTTATTTAAAGGGTGCGTTATAAATA
CGACAAATGTTGCAAATATGGAAGCTGTCGTAACGAAAATTACAGGTTCAGCTTGGCTTATGGGGATGCATAGATTTTTT
TACAATGAAAAGGATCCACTGAAAGAAGGATTTTTGCTAATTCCGCCGATGGAACATGAAACGGAGGATGTAAAATGA

Upstream 100 bases:

>100_bases
TTACAGGGAAAGTGATTGAAGAGTTATTAAATGAAAAAGAAACAATCATTCCTATTGAACCACTTCGTTTGAGTCGTTTT
ACAGAAAGGGTGTTAAACGG

Downstream 100 bases:

>100_bases
ACATTCAAAAAATGTATACAGCAGTAGACGTACACGTAAATGGCGAGGCATTCCGTGTAATAAAAGATGTACCATGCAAG
TACTACTACAATTTAGAGCA

Product: proline racemase

Products: D-proline

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRTQKVFTTIDTHTGGNPTRTLISGLPKLLGETMAEKMLHMKKEYDWIRKLLMNEPRGHDVMSGALLTDPCHPDADIGVI
YIETGGYLPMCGHDTIGVCTALIESGLIPVVEPITSLKLDTPAGLVEVDIFVRDGKAKEVSFCNIPAFVLKHITVDVENI
GTVEADIAYGGNFYAIIDAKSVGLELVPERASTIIDKAIHIRNIINERFEIIHPEYSFIRGLTHVEFYTDPTHESAHVKN
TVVVPPGGIDRSPCGTGTSAKLAVLYANQKIEMNEEFVHESIVGSLFKGCVINTTNVANMEAVVTKITGSAWLMGMHRFF
YNEKDPLKEGFLLIPPMEHETEDVK

Sequences:

>Translated_345_residues
MRTQKVFTTIDTHTGGNPTRTLISGLPKLLGETMAEKMLHMKKEYDWIRKLLMNEPRGHDVMSGALLTDPCHPDADIGVI
YIETGGYLPMCGHDTIGVCTALIESGLIPVVEPITSLKLDTPAGLVEVDIFVRDGKAKEVSFCNIPAFVLKHITVDVENI
GTVEADIAYGGNFYAIIDAKSVGLELVPERASTIIDKAIHIRNIINERFEIIHPEYSFIRGLTHVEFYTDPTHESAHVKN
TVVVPPGGIDRSPCGTGTSAKLAVLYANQKIEMNEEFVHESIVGSLFKGCVINTTNVANMEAVVTKITGSAWLMGMHRFF
YNEKDPLKEGFLLIPPMEHETEDVK
>Mature_345_residues
MRTQKVFTTIDTHTGGNPTRTLISGLPKLLGETMAEKMLHMKKEYDWIRKLLMNEPRGHDVMSGALLTDPCHPDADIGVI
YIETGGYLPMCGHDTIGVCTALIESGLIPVVEPITSLKLDTPAGLVEVDIFVRDGKAKEVSFCNIPAFVLKHITVDVENI
GTVEADIAYGGNFYAIIDAKSVGLELVPERASTIIDKAIHIRNIINERFEIIHPEYSFIRGLTHVEFYTDPTHESAHVKN
TVVVPPGGIDRSPCGTGTSAKLAVLYANQKIEMNEEFVHESIVGSLFKGCVINTTNVANMEAVVTKITGSAWLMGMHRFF
YNEKDPLKEGFLLIPPMEHETEDVK

Specific function: Unknown

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=337, Percent_Identity=33.5311572700297, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: 5.1.1.4

Molecular weight: Translated: 38060; Mature: 38060

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTQKVFTTIDTHTGGNPTRTLISGLPKLLGETMAEKMLHMKKEYDWIRKLLMNEPRGHD
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VMSGALLTDPCHPDADIGVIYIETGGYLPMCGHDTIGVCTALIESGLIPVVEPITSLKLD
HHCCCEEECCCCCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHEECC
TPAGLVEVDIFVRDGKAKEVSFCNIPAFVLKHITVDVENIGTVEADIAYGGNFYAIIDAK
CCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHEEEHHHCCCEEEEEEECCCEEEEEECC
SVGLELVPERASTIIDKAIHIRNIINERFEIIHPEYSFIRGLTHVEFYTDPTHESAHVKN
CCCEEECCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCEEEEEEECCCCCCCCCCE
TVVVPPGGIDRSPCGTGTSAKLAVLYANQKIEMNEEFVHESIVGSLFKGCVINTTNVANM
EEEECCCCCCCCCCCCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCEEECCCCCHH
EAVVTKITGSAWLMGMHRFFYNEKDPLKEGFLLIPPMEHETEDVK
HHHHHHHCCHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MRTQKVFTTIDTHTGGNPTRTLISGLPKLLGETMAEKMLHMKKEYDWIRKLLMNEPRGHD
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VMSGALLTDPCHPDADIGVIYIETGGYLPMCGHDTIGVCTALIESGLIPVVEPITSLKLD
HHCCCEEECCCCCCCCEEEEEEECCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHEECC
TPAGLVEVDIFVRDGKAKEVSFCNIPAFVLKHITVDVENIGTVEADIAYGGNFYAIIDAK
CCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHEEEHHHCCCEEEEEEECCCEEEEEECC
SVGLELVPERASTIIDKAIHIRNIINERFEIIHPEYSFIRGLTHVEFYTDPTHESAHVKN
CCCEEECCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCEEEEEEECCCCCCCCCCE
TVVVPPGGIDRSPCGTGTSAKLAVLYANQKIEMNEEFVHESIVGSLFKGCVINTTNVANM
EEEECCCCCCCCCCCCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCEEECCCCCHH
EAVVTKITGSAWLMGMHRFFYNEKDPLKEGFLLIPPMEHETEDVK
HHHHHHHCCHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-proline

Specific reaction: L-proline = D-proline

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]