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The map label for this gene is gntR [H]

Identifier: 118478105

GI number: 118478105

Start: 2628085

End: 2629518

Strand: Direct

Name: gntR [H]

Synonym: BALH_2461

Alternate gene names: 118478105

Gene position: 2628085-2629518 (Clockwise)

Preceding gene: 118478102

Following gene: 118478106

Centisome position: 49.99

GC content: 34.24

Gene sequence:

>1434_bases
ATGAAGATTGTACTGCGTAAAGAATCCAACATACCGTATTACAAGCAAATATATATGCAAATCGTTGAAAGAGTACAAAG
TGGCATGCTTTCACATGGTGACTCACTTCCATCTTTACGCTCTATGGCCGAAGATTTACAGATTAGCCTATTAACTGTTC
GTAAGGCGTATAAACAGCTAGAAAAGAAAGAATATATACGCATTGAACAAGGTAAAGGTGCTTATATACATAAACATGTA
AAGAAAGATTCCAAACCAATTCCGTATAAATGGCAACAAACGAAAACGATTAATGTTATGCGATCTCAATATGCAATGAA
TCAGCACCGGAAATATTACGATTTTTCACAAGCGATTTTATATCCACGTCTATTGCCAAATCCATTCTTGGCAGACGAAA
TGCATAAAATACTTAATAAAGACCAGATGATCCTAGCAACTTATGGGCCAGTTCAAGGAGATTATGAACTACGAGTTGAA
ATAGCAAAATACTTACATGAACACCAAAACTTAGTGACAGACCCATCCCAGTTATTAATTACAAGCGGCGCACAACAAGG
AATTGATTTAATTGCTCAAACATTATTAAAACCTGGTGATATTGTGTTAGTGGAAAGTCCGTGTTATAGTGCTGCGCTTG
ATATTTTCATCAATAAAGGGGCTCAAATTATACCTGTTTCTCTAGATAATCATGGGGTTCGATCCGATTTAATCGATGAT
ATTTGTCAAAGTAAAAATCCCGTTTTATTGTATACGAATCCAACTTTCCAGAACCCGACAGGTACAGTAATGAGTAAAGA
ACGAAGAATGGAACTTATAGAACTAGCAGAACTATATAAGTTTTTTATAATTGAAGATGATTCTTTCGGTGAAATATATT
TTGAGGGTGCGACTGTTCCCCCTCCGATTAAAAATTTTGATACAAACGGTCACGTACTATATATAAAAGGATTTAGTAAA
ACGTTAGCACCAGGACTGCGTATCGCATCACTTATTGCTGATGGCCCTATTTTCGAATGGCTATATGCTGTAAAAGGTTC
AATGGATATCGGTAGTCCTTTATTAACACAAAAAGCACTTCTACCGTTTTTGCGTGCAGAACGTATGAAACATCATTTAG
AAAAATTACGTACAGCTTTACAAATTAGACGTGATATAACGATTGATATGTTATCACCACTTAAAGAAATACAATTTGAA
ATACCTGATGGCGGCTTTAATTTATGGATTACTCTTCCTAATTCGATAGATCCTTTTACTTTATTACAAAAAGCAAATGA
AGTAGATGTTTCTTTTTTACCGGGAACAGCTTGTCTATTACATAACGATATAACTCATAACCAATTCAGGATTAGCTATT
CTATGTTAAATGAAAAAGATATGTTGATTGGTTTAGAGAAATTACACGATACAATAAGAAACTATACACTTTAA

Upstream 100 bases:

>100_bases
GTATAACAGTGTATCTATGTATATAACAGTTGCCTTAAATAGTAGTTGATTCTATATATATTTTTCGCTTAAATTAAATA
AAAACGAAAAAGGTGAAACC

Downstream 100 bases:

>100_bases
AAGCATATGCACAATCCTTGTAAGCTAACAAGTAAATACCCCAAAATATTTTTGTTTTGGGGTATAAAGAAATTTTGAAG
TATGTTAAGTCATTACTATT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
IAKYLHEHQNLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEGATVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFEWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDITHNQFRISYSMLNEKDMLIGLEKLHDTIRNYTL

Sequences:

>Translated_477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
IAKYLHEHQNLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEGATVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFEWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDITHNQFRISYSMLNEKDMLIGLEKLHDTIRNYTL
>Mature_477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
IAKYLHEHQNLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEGATVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFEWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDITHNQFRISYSMLNEKDMLIGLEKLHDTIRNYTL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=352, Percent_Identity=29.2613636363636, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI33469970, Length=352, Percent_Identity=29.2613636363636, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1790797, Length=437, Percent_Identity=26.0869565217391, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1787710, Length=434, Percent_Identity=28.8018433179723, Blast_Score=156, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6321236, Length=384, Percent_Identity=24.7395833333333, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321929, Length=195, Percent_Identity=24.1025641025641, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356535, Length=366, Percent_Identity=27.5956284153005, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54640; Mature: 54640

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
HHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVEIAKYLHEHQNLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEGATVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFEWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLHNDITHNQFRISYSMLNEKDMLIGLEKLHDTIRNYTL
HHHCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
HHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVEIAKYLHEHQNLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEGATVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFEWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLHNDITHNQFRISYSMLNEKDMLIGLEKLHDTIRNYTL
HHHCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]