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The map label for this gene is CYP106A2 [H]

Identifier: 118478017

GI number: 118478017

Start: 2539438

End: 2540652

Strand: Direct

Name: CYP106A2 [H]

Synonym: BALH_2368

Alternate gene names: 118478017

Gene position: 2539438-2540652 (Clockwise)

Preceding gene: 118478015

Following gene: 118478018

Centisome position: 48.31

GC content: 33.91

Gene sequence:

>1215_bases
ATGGATTCGCCTGAAAATGTGATTTTAGTTCATGAAATTTCAAAGCTGAAAACGAAAGAAGAATTGTGGAATCCGTATGA
GTGGTATCAATTTATGAGGGATAATCACCCGGTACATTATGATGATGAGCAAGATGTTTGGAATGTTTTTTTATATGATG
ATGTAAATCGAGTCTTATCGGATTATCGCTTATTTTCAAGTAGAAGGGAACGAAGACAATTTGCAATCCCACCTTTAGAA
ACTAGGATAAATATTAACTCCACTGATCCACCAGAACATCGCAACGTACGTTCTATCGTTTCTAAAGCATTTACTCCAAG
AAGTTTAGAACAATGGAAACCTCGAATACAGTCTATCGCAAATGAACTTGTAAAAGATATTGAAAACTGTAGTGAAGTTG
ATATCGTTGAACAGTTTGCTGCTCCTTTACCTGTTACCGTCATATCCGATTTATTAGGAGTGCCAACAACTGACCGTAAA
AAGATTAAAACATGGTCTGATATTCTATTTATGCCGTATAGTAAAGAAAAGTTTAATGATCTGGATGCAAAAAAGGGGAT
AGCACTAAATGAATTTAAAGCATATCTTCTACCGATCGTTCAGGAAAAGAGATACTATTTAACCGATGATATTATCTCTG
ATTTAATACGAGCTGAATATGAAGGTGAAAGATTAACTGATGAAGAAATTGTTACTTTTTCTTTAGGCTTATTAGCCGCG
GGTAATGAAACAACTACAAATTTAATCATTAATAGTTTTTACTGCTTTTTAGTGGACTCACCTGCAACATATAAAGAATT
AAGAGAAAAACCTAAATTAATTTCGAAAGCGATTGAGGAAGTATTACGCTATCGCTTTCCGGTTACATTAGCTAGAAGAA
TTACAGAGGACACCAATATATTTGGACCTTTAATGAAAAAGGATCAAATGGTTGTTGCGTGGGTTAGTGCAGCAAATTTA
GATGAGAAAAAGTTTTCACAAGCATCTAAGTTTAATATACATCGAATAGGAAATGAAAAGCATTTAACCTTTGGTAAGGG
CCCTCACTTTTGCTTAGGGGCACCACTTGCGCGTTTAGAAGCTGAGATTGCATTAACTACCTTTATAAATGCTTTTGAAA
AGATAGCATTATCTCCATCATTCAATATAGAACAATGTATATTGGAAAATGAACAAACTTTAAAATTCTTACCTATTCGC
CTAAAACCTCAATAA

Upstream 100 bases:

>100_bases
AATGCCCTTTAGTATATGTTAAAATAACATATGTTAGATTATACAACTTTGAACTACCGACCTATCACTTTTATTGTAAA
AGAAAAGGGAGGAAAGGACT

Downstream 100 bases:

>100_bases
ACTGTTCAGCAAGGTGCAAATTTACTGTACCTTGTTTTTTTATTTCTCAATTGTAAAATTTTAGTTAGTTATTTAGTATG
GAAGTGTGTAAATAAGAGTA

Product: cytochrome P450

Products: NA

Alternate protein names: Steroid 15-beta-hydroxylase; Steroid 15-beta-monooxygenase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDSPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVHYDDEQDVWNVFLYDDVNRVLSDYRLFSSRRERRQFAIPPLE
TRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQSIANELVKDIENCSEVDIVEQFAAPLPVTVISDLLGVPTTDRK
KIKTWSDILFMPYSKEKFNDLDAKKGIALNEFKAYLLPIVQEKRYYLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLAA
GNETTTNLIINSFYCFLVDSPATYKELREKPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANL
DEKKFSQASKFNIHRIGNEKHLTFGKGPHFCLGAPLARLEAEIALTTFINAFEKIALSPSFNIEQCILENEQTLKFLPIR
LKPQ

Sequences:

>Translated_404_residues
MDSPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVHYDDEQDVWNVFLYDDVNRVLSDYRLFSSRRERRQFAIPPLE
TRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQSIANELVKDIENCSEVDIVEQFAAPLPVTVISDLLGVPTTDRK
KIKTWSDILFMPYSKEKFNDLDAKKGIALNEFKAYLLPIVQEKRYYLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLAA
GNETTTNLIINSFYCFLVDSPATYKELREKPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANL
DEKKFSQASKFNIHRIGNEKHLTFGKGPHFCLGAPLARLEAEIALTTFINAFEKIALSPSFNIEQCILENEQTLKFLPIR
LKPQ
>Mature_404_residues
MDSPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVHYDDEQDVWNVFLYDDVNRVLSDYRLFSSRRERRQFAIPPLE
TRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQSIANELVKDIENCSEVDIVEQFAAPLPVTVISDLLGVPTTDRK
KIKTWSDILFMPYSKEKFNDLDAKKGIALNEFKAYLLPIVQEKRYYLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLAA
GNETTTNLIINSFYCFLVDSPATYKELREKPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANL
DEKKFSQASKFNIHRIGNEKHLTFGKGPHFCLGAPLARLEAEIALTTFINAFEKIALSPSFNIEQCILENEQTLKFLPIR
LKPQ

Specific function: Has the capacity to hydroxylate certain steroids in the 15-beta position [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46925; Mature: 46925

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVHYDDEQDVWNVFLYDDVNRVLS
CCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHH
DYRLFSSRRERRQFAIPPLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQSIA
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NELVKDIENCSEVDIVEQFAAPLPVTVISDLLGVPTTDRKKIKTWSDILFMPYSKEKFND
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHEEECCCCHHHHCC
LDAKKGIALNEFKAYLLPIVQEKRYYLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLAA
CHHHCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCHHHHEEEEHEEEC
GNETTTNLIINSFYCFLVDSPATYKELREKPKLISKAIEEVLRYRFPVTLARRITEDTNI
CCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
FGPLMKKDQMVVAWVSAANLDEKKFSQASKFNIHRIGNEKHLTFGKGPHFCLGAPLARLE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCHHHHH
AEIALTTFINAFEKIALSPSFNIEQCILENEQTLKFLPIRLKPQ
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCC
>Mature Secondary Structure
MDSPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVHYDDEQDVWNVFLYDDVNRVLS
CCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHH
DYRLFSSRRERRQFAIPPLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQSIA
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NELVKDIENCSEVDIVEQFAAPLPVTVISDLLGVPTTDRKKIKTWSDILFMPYSKEKFND
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHEEECCCCHHHHCC
LDAKKGIALNEFKAYLLPIVQEKRYYLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLAA
CHHHCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCCCCHHHHEEEEHEEEC
GNETTTNLIINSFYCFLVDSPATYKELREKPKLISKAIEEVLRYRFPVTLARRITEDTNI
CCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
FGPLMKKDQMVVAWVSAANLDEKKFSQASKFNIHRIGNEKHLTFGKGPHFCLGAPLARLE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCHHHHH
AEIALTTFINAFEKIALSPSFNIEQCILENEQTLKFLPIRLKPQ
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8232201; 109432; 6797409 [H]