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The map label for this gene is cat [H]

Identifier: 118477900

GI number: 118477900

Start: 2402831

End: 2403535

Strand: Direct

Name: cat [H]

Synonym: BALH_2245

Alternate gene names: 118477900

Gene position: 2402831-2403535 (Clockwise)

Preceding gene: 118477898

Following gene: 118477901

Centisome position: 45.71

GC content: 35.89

Gene sequence:

>705_bases
GTGAATTACAAGAATCTACAATACTTAGAAGCGAGGAATAAAGGTATGAGGCATCCATTATATAATCATTGGTCAGAAAC
AAAGTATATTAAAGATATAGTAACAAATCCACTCATTGAGGTAGGAGATTACTCCTATTATTCAGGGTATTATGGTCATC
AAAATTTTGAAGATGGCTGTGTAAGGTATTTGTGGGGGGATGCTAAGTCCCGAGCGCTGTTCAATCCAATTGAACAGATG
GGATGGCATCTTGATAAACTCATTATTGGGAATTATGTTTGTATTGCCAGTGGAGTAGTCATTTTAATGGGTGGTAATCA
TAATCATCACTCAGAATGGATTACAGTATATCCATTCGCTGAGCAAATTGAACATTCATATGAACCGAAGGGTGATACAG
TCATTAAAAGTGATGCTTGGATTGGAATGAATGCTATTATTATGCCTGGTGTTACAATTGGTGAAGGTGCAATCGTTGCA
GCAGGATCTGTCGTAAGTAAAGATGTTCCGCCGTATACAATAGTTGGTGGAAATCCTGCTAAGGAAATAAAGAAGCAGTT
CACTGATACGGAAATGAATATGCTAATGGAAATGCGTTGGTTTGATTGGGAGAGAGAATTAGTTGAGAAGGCAATGCCTA
TATTATCTAGCTCATCTATTAAACTCTTATATGATTTTTATAAAAAGGAAGTAAAAAATAGATAA

Upstream 100 bases:

>100_bases
TTAACACGTTATGATTTTTTTATTATAACAGAAAGGCTTGAATATAATGATTCGTCGTTTGAGAAAGCTAAAAAATGTAG
CAGTCGTAGTAAGCTTCTAA

Downstream 100 bases:

>100_bases
GTCTGTGAACAAAACTACATTCTATATAGGATGTAGTTTTTTATTATAAAAAATTAATAGTCTAGACTAAGGAAAATTCA
ACTCTGGCATGAGTATAGCA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNYKNLQYLEARNKGMRHPLYNHWSETKYIKDIVTNPLIEVGDYSYYSGYYGHQNFEDGCVRYLWGDAKSRALFNPIEQM
GWHLDKLIIGNYVCIASGVVILMGGNHNHHSEWITVYPFAEQIEHSYEPKGDTVIKSDAWIGMNAIIMPGVTIGEGAIVA
AGSVVSKDVPPYTIVGGNPAKEIKKQFTDTEMNMLMEMRWFDWERELVEKAMPILSSSSIKLLYDFYKKEVKNR

Sequences:

>Translated_234_residues
MNYKNLQYLEARNKGMRHPLYNHWSETKYIKDIVTNPLIEVGDYSYYSGYYGHQNFEDGCVRYLWGDAKSRALFNPIEQM
GWHLDKLIIGNYVCIASGVVILMGGNHNHHSEWITVYPFAEQIEHSYEPKGDTVIKSDAWIGMNAIIMPGVTIGEGAIVA
AGSVVSKDVPPYTIVGGNPAKEIKKQFTDTEMNMLMEMRWFDWERELVEKAMPILSSSSIKLLYDFYKKEVKNR
>Mature_234_residues
MNYKNLQYLEARNKGMRHPLYNHWSETKYIKDIVTNPLIEVGDYSYYSGYYGHQNFEDGCVRYLWGDAKSRALFNPIEQM
GWHLDKLIIGNYVCIASGVVILMGGNHNHHSEWITVYPFAEQIEHSYEPKGDTVIKSDAWIGMNAIIMPGVTIGEGAIVA
AGSVVSKDVPPYTIVGGNPAKEIKKQFTDTEMNMLMEMRWFDWERELVEKAMPILSSSSIKLLYDFYKKEVKNR

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=101, Percent_Identity=36.6336633663366, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 26903; Mature: 26903

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKNLQYLEARNKGMRHPLYNHWSETKYIKDIVTNPLIEVGDYSYYSGYYGHQNFEDGC
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHH
VRYLWGDAKSRALFNPIEQMGWHLDKLIIGNYVCIASGVVILMGGNHNHHSEWITVYPFA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCEEEEECCH
EQIEHSYEPKGDTVIKSDAWIGMNAIIMPGVTIGEGAIVAAGSVVSKDVPPYTIVGGNPA
HHHHHCCCCCCCEEEECCCCCCCCEEEECCEEECCCCEEECCHHHHCCCCCEEEECCCHH
KEIKKQFTDTEMNMLMEMRWFDWERELVEKAMPILSSSSIKLLYDFYKKEVKNR
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYKNLQYLEARNKGMRHPLYNHWSETKYIKDIVTNPLIEVGDYSYYSGYYGHQNFEDGC
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHH
VRYLWGDAKSRALFNPIEQMGWHLDKLIIGNYVCIASGVVILMGGNHNHHSEWITVYPFA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCEEEEECCH
EQIEHSYEPKGDTVIKSDAWIGMNAIIMPGVTIGEGAIVAAGSVVSKDVPPYTIVGGNPA
HHHHHCCCCCCCEEEECCCCCCCCEEEECCEEECCCCEEECCHHHHCCCCCEEEECCCHH
KEIKKQFTDTEMNMLMEMRWFDWERELVEKAMPILSSSSIKLLYDFYKKEVKNR
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]