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The map label for this gene is ampC [C]

Identifier: 118477698

GI number: 118477698

Start: 2179855

End: 2181012

Strand: Direct

Name: ampC [C]

Synonym: BALH_2032

Alternate gene names: 118477698

Gene position: 2179855-2181012 (Clockwise)

Preceding gene: 118477695

Following gene: 118477699

Centisome position: 41.47

GC content: 39.46

Gene sequence:

>1158_bases
ATGAAAACATGCAGTAAAATTACATGTGCAAGTCTATCACTTTTAATAGCTGGAAGTTCCCTGTTATACATAACACCAGC
CTCAATTGTAAAAGCAGAACCTACGCAAAATGTATCTAGTTCGTTACAAACAAGTATGCAAAGCGATCGTACTTCCGTTA
AGAAAGCAATACGGGATGCACTACAACTTGGATACCCGGGAATACTCGCTAACATTTCTAAGGGTGGTAAAACCTGGAGT
TATACCGCTGGGTTAGCAGATGTGAGAACCAAGAAACCAATGAAAGCAGATTTTCGCTTTCGTATTGGCAGTGTGACGAA
AACGTTCATTGCAACAGTTCTACTTCAATTATCTGGAGAGAACCGTTTGAATCTAGATGACTCCATTGAAAAATGGTTGC
CTGGTGTCATTCAAGGAAACGGATATGATGGTAACCAAATTACGATCCGGCAAATATTGAATCATACAAGTGGTATTGCT
GACTATATAAATTCAAAAGACTTTGATATTACGGATATAAAAAAATCGTATACGGCTGAAGAATTTGTAAAGATGGGGAT
TTCTCTTCCCCCAGACTTTGCTCCAGGGAAGGGTTGGTCTTATTCAAATACAGGATACGTAATACTAGGTATCCTTATTG
AAAAAGTAACAGGAAACAGCTATGCGGAAGAGGTTGAAAATCGGATTATTGAACCGCTTGATTTATCAAATACATTCCTA
CCTGGCAATTCAAGCGTGATTCCAGGCACCAAGCATGCCCGTGGCTATTTGCAACGAGACGGAGCAAGTGAGCTAAAAGA
CGTTACTTATATTAACCCAGGTAGCTCGGATGGAGATATGATTTCTACTGCTGACGACTTAAACAAATTCTTCTCTTACT
TACTAGGTGGCAAATTACTGAAGGAACAGCAATTAAAACAAATGCTTACTACAGTTCCTACAGAAAGAGAAGGAACTGGA
TATGGTCTTGGAATCCTTGAAATTAAGCTTCCAAATGGTATCTCGGTATGGGGACACAGAGGGGGCGTTCCAGGGTTTTC
CACTTTTGTTGGTGGAACACTTGGAGGCAAGCATACATTGGCCGTCAATTTGAACAGCTTTAATTTTAGTAATCCTGATC
CTTTTAAAAGTATTTTACTTGCTGAATTTAGGAAGTAG

Upstream 100 bases:

>100_bases
AGTGTTGACTTTTATCATTGGGAGAGTTGATAGCTGTGTGGTTAGTATATGACATACCTATCAACCATCAATACAATTTA
AATAGAGGAGAGGATGCTTT

Downstream 100 bases:

>100_bases
GCAAAAAGGAAAAACGGATAAGTTTTGTCATAGTTTTATAGTTTAAAATATACCATTTTGGTGCAAAAAACAACTTGCTC
TAAAAAAATTTAATACTCGT

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQRDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGISVWGHRGGVPGFSTFVGGTLGGKHTLAVNLNSFNFSNPDPFKSILLAEFRK

Sequences:

>Translated_385_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQRDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGISVWGHRGGVPGFSTFVGGTLGGKHTLAVNLNSFNFSNPDPFKSILLAEFRK
>Mature_385_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
PGNSSVIPGTKHARGYLQRDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTG
YGLGILEIKLPNGISVWGHRGGVPGFSTFVGGTLGGKHTLAVNLNSFNFSNPDPFKSILLAEFRK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=272, Percent_Identity=23.8970588235294, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082101, Length=238, Percent_Identity=25.6302521008403, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=339, Percent_Identity=26.8436578171091, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550934, Length=314, Percent_Identity=25.796178343949, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565630, Length=243, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41768; Mature: 41768

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDA
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILANISKGGKTWSYTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHEEECCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
PGNSSVIPGTKHARGYLQRDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLL
CCCCCCCCCCHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTEREGTGYGLGILEIKLPNGISVWGHRGGVPGFSTFVGGTLGGKHTL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEE
AVNLNSFNFSNPDPFKSILLAEFRK
EEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDA
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILANISKGGKTWSYTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHEEECCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIIEPLDLSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
PGNSSVIPGTKHARGYLQRDGASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLL
CCCCCCCCCCHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTEREGTGYGLGILEIKLPNGISVWGHRGGVPGFSTFVGGTLGGKHTL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEE
AVNLNSFNFSNPDPFKSILLAEFRK
EEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]