Click here to switch to the map view.

The map label for this gene is adh [H]

Identifier: 118477695

GI number: 118477695

Start: 2176100

End: 2177137

Strand: Direct

Name: adh [H]

Synonym: BALH_2027

Alternate gene names: 118477695

Gene position: 2176100-2177137 (Clockwise)

Preceding gene: 118477694

Following gene: 118477698

Centisome position: 41.39

GC content: 38.82

Gene sequence:

>1038_bases
ATGAAAGCAGTAGTAGTTAATAAAAATAGTAAAGCCAATATTGAGGTTGTTGAAAAGGAATTACGTCCGCTACACTCAGG
TGAAGCACTAGTAGATGTAGAGTATTGTGGGGTTTGTCATACTGATTTACACGTTGCAAATCATGATTTTGGAAACACAG
ATGGCCGTATTCTTGGTCATGAGGGTGTAGGTATTGTGATGAAAATTGCTGATGATGTTACTTCACTAAAGGTAGGTGAT
CGTGTAAGTATTGCATGGATGTTCCAATCTTGTGGACGTTGTGAATATTGCGTGACTGGTAGAGAAACATTTTGCCGTGA
AGTTAAGAATGCTGGTTATTCAGTAGATGGTGGTATGGCTGAACAATGTATTGTTACAGCTGATTATGCAGTGAAAGTAC
CAGAAGGATTAGATCCTGCTCAAGCATCATCGATCACATGTGCGGGCGTTACTACATATAAAGCTATAAAAGTATCTGAT
ATTAAACCTGGTCAACCGATCGTAATCTATGGTTGTGGTGGATTAGGTAACTTAGCTATCCAATATGCTAAAAATGTATT
TGGTGCAAAGGTAATTGCAGTAGATATTAATGACGATAAACTAGCCTTAGCAAAAGAGGTTGGTGCTGATATGACAATCA
ATCCAATTTCTCAAGGTCCTGCTGATAAGATTATTCAAGAGGAGTTTGGTGGTGCTTATGCTGCTGTAGTAACAGCTGTT
TCAAAGGTAGCATTCAACTCAGCAGTTGACGCAGTACGTGCTTGTGGTAAAGTCGTTGCAGTAGGTTTACCAGTAGAAAC
TATGGATTTGAACATTCCGCGCCTTGTACTAGATGGAATTGAAGTAGTTGGTTCTTTAGTCGGTACTCGTAAGGATCTAG
AAGAGGCGTTTATGTTCGGGGCAGAAGGAAAAGTAGTGCCAGTTGTTCAAACTTGTTCTTTAGATACAGTACAAAATGTA
TTCGAAGAAATGGAACAAGGTAGAATTCAAGGGCGTATGGTAATCGATTTTAAACAGAACAATTGTGATTGCAAATAA

Upstream 100 bases:

>100_bases
TGAACACTTACATTTGGCATAATGATTAGCCAAACTAGTGAAGACAGAAGTTGTGAGATGAACTCATTAAAATTCTAAAA
CACTAAAGGGGAGATCACAT

Downstream 100 bases:

>100_bases
TTCACATTAAACATAAAAAATATGAGTCTAACAAAGTACATGTAAAAAAGTTAGACGGTATAAAAAAGATGATCTCTGTA
TTCAATAGGGATCATCTTTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: ADH [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKAVVVNKNSKANIEVVEKELRPLHSGEALVDVEYCGVCHTDLHVANHDFGNTDGRILGHEGVGIVMKIADDVTSLKVGD
RVSIAWMFQSCGRCEYCVTGRETFCREVKNAGYSVDGGMAEQCIVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSD
IKPGQPIVIYGCGGLGNLAIQYAKNVFGAKVIAVDINDDKLALAKEVGADMTINPISQGPADKIIQEEFGGAYAAVVTAV
SKVAFNSAVDAVRACGKVVAVGLPVETMDLNIPRLVLDGIEVVGSLVGTRKDLEEAFMFGAEGKVVPVVQTCSLDTVQNV
FEEMEQGRIQGRMVIDFKQNNCDCK

Sequences:

>Translated_345_residues
MKAVVVNKNSKANIEVVEKELRPLHSGEALVDVEYCGVCHTDLHVANHDFGNTDGRILGHEGVGIVMKIADDVTSLKVGD
RVSIAWMFQSCGRCEYCVTGRETFCREVKNAGYSVDGGMAEQCIVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSD
IKPGQPIVIYGCGGLGNLAIQYAKNVFGAKVIAVDINDDKLALAKEVGADMTINPISQGPADKIIQEEFGGAYAAVVTAV
SKVAFNSAVDAVRACGKVVAVGLPVETMDLNIPRLVLDGIEVVGSLVGTRKDLEEAFMFGAEGKVVPVVQTCSLDTVQNV
FEEMEQGRIQGRMVIDFKQNNCDCK
>Mature_345_residues
MKAVVVNKNSKANIEVVEKELRPLHSGEALVDVEYCGVCHTDLHVANHDFGNTDGRILGHEGVGIVMKIADDVTSLKVGD
RVSIAWMFQSCGRCEYCVTGRETFCREVKNAGYSVDGGMAEQCIVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSD
IKPGQPIVIYGCGGLGNLAIQYAKNVFGAKVIAVDINDDKLALAKEVGADMTINPISQGPADKIIQEEFGGAYAAVVTAV
SKVAFNSAVDAVRACGKVVAVGLPVETMDLNIPRLVLDGIEVVGSLVGTRKDLEEAFMFGAEGKVVPVVQTCSLDTVQNV
FEEMEQGRIQGRMVIDFKQNNCDCK

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=311, Percent_Identity=28.2958199356913, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4501929, Length=310, Percent_Identity=30, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI34577061, Length=310, Percent_Identity=28.7096774193548, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI262073058, Length=320, Percent_Identity=26.875, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI71743840, Length=320, Percent_Identity=26.875, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI71565154, Length=225, Percent_Identity=30.6666666666667, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI156523966, Length=361, Percent_Identity=24.9307479224377, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4501939, Length=361, Percent_Identity=24.9307479224377, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI71565152, Length=348, Percent_Identity=24.1379310344828, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI156627571, Length=265, Percent_Identity=23.3962264150943, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081918, Length=339, Percent_Identity=67.8466076696165, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI87082401, Length=336, Percent_Identity=26.1904761904762, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787863, Length=281, Percent_Identity=29.8932384341637, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790045, Length=349, Percent_Identity=24.6418338108883, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786518, Length=346, Percent_Identity=26.0115606936416, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788073, Length=271, Percent_Identity=29.1512915129151, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI226510992, Length=312, Percent_Identity=25.6410256410256, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786552, Length=351, Percent_Identity=27.3504273504274, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082125, Length=328, Percent_Identity=25.3048780487805, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788075, Length=336, Percent_Identity=25.297619047619, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790718, Length=327, Percent_Identity=25.6880733944954, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788407, Length=215, Percent_Identity=28.8372093023256, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786825, Length=251, Percent_Identity=28.2868525896414, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=315, Percent_Identity=36.1904761904762, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17562584, Length=329, Percent_Identity=35.5623100303951, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17562582, Length=315, Percent_Identity=35.8730158730159, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17562876, Length=256, Percent_Identity=30.078125, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=192, Percent_Identity=32.2916666666667, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25146526, Length=258, Percent_Identity=29.0697674418605, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71997431, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565904, Length=233, Percent_Identity=28.755364806867, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=314, Percent_Identity=37.5796178343949, Blast_Score=200, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=35.0148367952522, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323961, Length=314, Percent_Identity=36.624203821656, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319621, Length=314, Percent_Identity=36.9426751592357, Blast_Score=195, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6319949, Length=346, Percent_Identity=27.7456647398844, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323980, Length=337, Percent_Identity=25.8160237388724, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320033, Length=263, Percent_Identity=30.7984790874525, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=290, Percent_Identity=25.5172413793103, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=286, Percent_Identity=28.6713286713287, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=286, Percent_Identity=28.3216783216783, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323099, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=331, Percent_Identity=24.773413897281, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17137530, Length=229, Percent_Identity=28.82096069869, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737897, Length=208, Percent_Identity=29.8076923076923, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737895, Length=233, Percent_Identity=27.0386266094421, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36741; Mature: 36741

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVVNKNSKANIEVVEKELRPLHSGEALVDVEYCGVCHTDLHVANHDFGNTDGRILGH
CCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECCEEECCEEEECCCCCCCCCEEEEC
EGVGIVMKIADDVTSLKVGDRVSIAWMFQSCGRCEYCVTGRETFCREVKNAGYSVDGGMA
CCCEEEEEECCCHHHEECCCCEEEEEEHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCC
EQCIVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSDIKPGQPIVIYGCGGLGNLAI
CCEEEEECEEEECCCCCCCCCCCCEEEECEEEEEEEEEECCCCCCCEEEEECCCHHHHHH
QYAKNVFGAKVIAVDINDDKLALAKEVGADMTINPISQGPADKIIQEEFGGAYAAVVTAV
HHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHH
SKVAFNSAVDAVRACGKVVAVGLPVETMDLNIPRLVLDGIEVVGSLVGTRKDLEEAFMFG
HHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
AEGKVVPVVQTCSLDTVQNVFEEMEQGRIQGRMVIDFKQNNCDCK
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKAVVVNKNSKANIEVVEKELRPLHSGEALVDVEYCGVCHTDLHVANHDFGNTDGRILGH
CCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECCEEECCEEEECCCCCCCCCEEEEC
EGVGIVMKIADDVTSLKVGDRVSIAWMFQSCGRCEYCVTGRETFCREVKNAGYSVDGGMA
CCCEEEEEECCCHHHEECCCCEEEEEEHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCC
EQCIVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSDIKPGQPIVIYGCGGLGNLAI
CCEEEEECEEEECCCCCCCCCCCCEEEECEEEEEEEEEECCCCCCCEEEEECCCHHHHHH
QYAKNVFGAKVIAVDINDDKLALAKEVGADMTINPISQGPADKIIQEEFGGAYAAVVTAV
HHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHH
SKVAFNSAVDAVRACGKVVAVGLPVETMDLNIPRLVLDGIEVVGSLVGTRKDLEEAFMFG
HHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
AEGKVVPVVQTCSLDTVQNVFEEMEQGRIQGRMVIDFKQNNCDCK
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA