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The map label for this gene is kdgR [H]

Identifier: 118477511

GI number: 118477511

Start: 1989331

End: 1990113

Strand: Direct

Name: kdgR [H]

Synonym: BALH_1836

Alternate gene names: 118477511

Gene position: 1989331-1990113 (Clockwise)

Preceding gene: 118477510

Following gene: 118477512

Centisome position: 37.84

GC content: 36.91

Gene sequence:

>783_bases
GTGAGAACTGTAACTGGAATAGGGGAGGTATATGATTTGATCGCTTCTATCAGTAAAATTTGCAAAATTCTAAATTGTTT
CACAAGTGATGAGCCTGTGCTAGGTAATTCGGAAATAGCGGAAAAGCTAAATATGAATGCAAGTACGGTTCATCATCTTG
TTCGTACGTTGTGTGCAGAAGGAATGCTCATACAAGATGAGCAAAGAAAATATAGATTAGGTTGGAAATTGTTAGAGTGG
GGAAATCAAGTCATGTTTCAGCAAGAGATATATAGTGGAGCGATTCCGCTTGTTGAAGAGCTAGTAAGAAATTTTAGTGG
TACTGTGCATATCGGTATGTTTGACCGTGGTGATGTTGTATTTATATTGAAAGTTTCATCGAAGGAGTCCGTTCAAATTT
CAACACATGTTGGATCAAGAGAGCCTGCATATTGTACAAGCACAGGGAAAGTGCTGCTTTCATTTCATTCATCACCCTTA
GAATATACTTCAGAAAAAGGGCTTTTACGACGAGCACCCAATACCATTACATGTGTCAAACAATTCCAAACAGAGTTACA
GAAAATTCGTAAGAAAGGTTATTCAATTAGTGATAACGAAAATGAGCATGGACTGTATGGAATTGCAGCTCCTATTCGAT
CTTATACTGGGAGAACTATTGCGGCGCTTAATATTGTTGGACCTATATCGTATATGCAAGGAAGTAACCGTGAAATCATA
ATTCAAAGTGTGATGAATACGGCAAATTTGATTTCAAAGGAATTTGGTTATTTGGAAATTTAA

Upstream 100 bases:

>100_bases
GCTTACATTTTTTATTTTGAAAAGGAAGGAGCAATAGATGATAGAAAGAATTTTACTGTTAGGATGTAATTCTTCTTATA
TTTTTAACAATATCTAGAAC

Downstream 100 bases:

>100_bases
CTTTAGAAGAAAAGAGATGAGTATCATTTATATACATGAGCAGTGTATACCTGAATTAACGGAATCTATTGTTTCAATTG
GAGCATTTGATGGTGTGCAT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRTVTGIGEVYDLIASISKICKILNCFTSDEPVLGNSEIAEKLNMNASTVHHLVRTLCAEGMLIQDEQRKYRLGWKLLEW
GNQVMFQQEIYSGAIPLVEELVRNFSGTVHIGMFDRGDVVFILKVSSKESVQISTHVGSREPAYCTSTGKVLLSFHSSPL
EYTSEKGLLRRAPNTITCVKQFQTELQKIRKKGYSISDNENEHGLYGIAAPIRSYTGRTIAALNIVGPISYMQGSNREII
IQSVMNTANLISKEFGYLEI

Sequences:

>Translated_260_residues
MRTVTGIGEVYDLIASISKICKILNCFTSDEPVLGNSEIAEKLNMNASTVHHLVRTLCAEGMLIQDEQRKYRLGWKLLEW
GNQVMFQQEIYSGAIPLVEELVRNFSGTVHIGMFDRGDVVFILKVSSKESVQISTHVGSREPAYCTSTGKVLLSFHSSPL
EYTSEKGLLRRAPNTITCVKQFQTELQKIRKKGYSISDNENEHGLYGIAAPIRSYTGRTIAALNIVGPISYMQGSNREII
IQSVMNTANLISKEFGYLEI
>Mature_260_residues
MRTVTGIGEVYDLIASISKICKILNCFTSDEPVLGNSEIAEKLNMNASTVHHLVRTLCAEGMLIQDEQRKYRLGWKLLEW
GNQVMFQQEIYSGAIPLVEELVRNFSGTVHIGMFDRGDVVFILKVSSKESVQISTHVGSREPAYCTSTGKVLLSFHSSPL
EYTSEKGLLRRAPNTITCVKQFQTELQKIRKKGYSISDNENEHGLYGIAAPIRSYTGRTIAALNIVGPISYMQGSNREII
IQSVMNTANLISKEFGYLEI

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=252, Percent_Identity=29.3650793650794, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786468, Length=254, Percent_Identity=27.5590551181102, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788581, Length=246, Percent_Identity=24.7967479674797, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790752, Length=224, Percent_Identity=27.2321428571429, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786715, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789999, Length=244, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082359, Length=222, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29045; Mature: 29045

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVTGIGEVYDLIASISKICKILNCFTSDEPVLGNSEIAEKLNMNASTVHHLVRTLCAE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GMLIQDEQRKYRLGWKLLEWGNQVMFQQEIYSGAIPLVEELVRNFSGTVHIGMFDRGDVV
CCEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCEE
FILKVSSKESVQISTHVGSREPAYCTSTGKVLLSFHSSPLEYTSEKGLLRRAPNTITCVK
EEEEECCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHCCCHHHHHH
QFQTELQKIRKKGYSISDNENEHGLYGIAAPIRSYTGRTIAALNIVGPISYMQGSNREII
HHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHCCCCEEEEEEECCCHHHHCCCCCHHH
IQSVMNTANLISKEFGYLEI
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTVTGIGEVYDLIASISKICKILNCFTSDEPVLGNSEIAEKLNMNASTVHHLVRTLCAE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GMLIQDEQRKYRLGWKLLEWGNQVMFQQEIYSGAIPLVEELVRNFSGTVHIGMFDRGDVV
CCEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCEE
FILKVSSKESVQISTHVGSREPAYCTSTGKVLLSFHSSPLEYTSEKGLLRRAPNTITCVK
EEEEECCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHCCCHHHHHH
QFQTELQKIRKKGYSISDNENEHGLYGIAAPIRSYTGRTIAALNIVGPISYMQGSNREII
HHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHCCCCEEEEEEECCCHHHHCCCCCHHH
IQSVMNTANLISKEFGYLEI
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]