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The map label for this gene is yrhP [H]

Identifier: 118477348

GI number: 118477348

Start: 1816846

End: 1817472

Strand: Direct

Name: yrhP [H]

Synonym: BALH_1666

Alternate gene names: 118477348

Gene position: 1816846-1817472 (Clockwise)

Preceding gene: 118477347

Following gene: 118477349

Centisome position: 34.56

GC content: 31.74

Gene sequence:

>627_bases
ATGGAAAATTATCTATTATTTATCCTTACAGCAATGCTAATCATAATGATGCCTGGTCCTGGTTTTGCACTAGTTACAAA
AAATACTATCTCGCATGGTAAAAATGGTGGGATAAAGACTGTTTTAGGAACGATATCTGGAATGATGATTCATACAATAA
TGGCTACGTTAGGACTCTCTGCTATCCTAATGAAATTTGCTATGTTATTTACATGTATAAAATATGCTGGGGCTGTTTAT
TTAATTTATTTAGCTGTAAAGTCAATTAAAAGTGCCTTACATAAAAAAGAAGATATGTCAGGTCCAATAGAAATGGACTC
TAAGAATATTGGGGCAATTAAAAGCTTTAGACAAGGATTTACTACGGCAATTTTAAACCCAAAAACTGCTGTGTTTTTCC
TTAGTTTTTTACCCCAATTTATTGTAAGTAATCAAAATCATTTCCTCCAATTTCTTTTATTAGGAGTCACATTTACGACT
TTGACAGCAATATGGTATTTACTTTACATCTCACTCATACGTCAATTAAGAACTTTTTTAAGAAAAGAACGAGTGAACCG
TATAATGGAGGGTATTACGGGCGCAGTATTATTAGTATTTGGGGTTAGATTATTTTTCCAAAAATAA

Upstream 100 bases:

>100_bases
TTGATAGATAAATTTCTGATCAAGCTTTTTATATTTAATATTTGAATGAAAAAAGCTATACTGTAAGCAAAACTAAAAAT
TGGAAAGGAAATACTAGCAC

Downstream 100 bases:

>100_bases
ATATGTATATGAAAAGAGAAATAATCACTATTGATTATTTCTCCATAGCCTGCAAAAAGGAATCCGTAAAGGATTCCTTT
TTTTACATTTAATGTTTTAA

Product: amino acid transporter LysE

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MENYLLFILTAMLIIMMPGPGFALVTKNTISHGKNGGIKTVLGTISGMMIHTIMATLGLSAILMKFAMLFTCIKYAGAVY
LIYLAVKSIKSALHKKEDMSGPIEMDSKNIGAIKSFRQGFTTAILNPKTAVFFLSFLPQFIVSNQNHFLQFLLLGVTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRIMEGITGAVLLVFGVRLFFQK

Sequences:

>Translated_208_residues
MENYLLFILTAMLIIMMPGPGFALVTKNTISHGKNGGIKTVLGTISGMMIHTIMATLGLSAILMKFAMLFTCIKYAGAVY
LIYLAVKSIKSALHKKEDMSGPIEMDSKNIGAIKSFRQGFTTAILNPKTAVFFLSFLPQFIVSNQNHFLQFLLLGVTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRIMEGITGAVLLVFGVRLFFQK
>Mature_208_residues
MENYLLFILTAMLIIMMPGPGFALVTKNTISHGKNGGIKTVLGTISGMMIHTIMATLGLSAILMKFAMLFTCIKYAGAVY
LIYLAVKSIKSALHKKEDMSGPIEMDSKNIGAIKSFRQGFTTAILNPKTAVFFLSFLPQFIVSNQNHFLQFLLLGVTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRIMEGITGAVLLVFGVRLFFQK

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=208, Percent_Identity=26.4423076923077, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788099, Length=205, Percent_Identity=28.780487804878, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI48994978, Length=210, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23289; Mature: 23289

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYLLFILTAMLIIMMPGPGFALVTKNTISHGKNGGIKTVLGTISGMMIHTIMATLGLS
CCCHHHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILMKFAMLFTCIKYAGAVYLIYLAVKSIKSALHKKEDMSGPIEMDSKNIGAIKSFRQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TTAILNPKTAVFFLSFLPQFIVSNQNHFLQFLLLGVTFTTLTAIWYLLYISLIRQLRTFL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKERVNRIMEGITGAVLLVFGVRLFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENYLLFILTAMLIIMMPGPGFALVTKNTISHGKNGGIKTVLGTISGMMIHTIMATLGLS
CCCHHHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILMKFAMLFTCIKYAGAVYLIYLAVKSIKSALHKKEDMSGPIEMDSKNIGAIKSFRQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TTAILNPKTAVFFLSFLPQFIVSNQNHFLQFLLLGVTFTTLTAIWYLLYISLIRQLRTFL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKERVNRIMEGITGAVLLVFGVRLFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]