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The map label for this gene is hblA [H]

Identifier: 118477347

GI number: 118477347

Start: 1815595

End: 1816683

Strand: Direct

Name: hblA [H]

Synonym: BALH_1665

Alternate gene names: 118477347

Gene position: 1815595-1816683 (Clockwise)

Preceding gene: 118477346

Following gene: 118477348

Centisome position: 34.54

GC content: 34.89

Gene sequence:

>1089_bases
GTGAAAAGTATGCAGAAACGATTTTATAAAAAATGTCTTTTAACATTAATGATTGCTGGAGTGGCAACGAGTAACGCATT
TCCTTTACATACTTTTGCAGCAGAACAAAACGTAAAAACATTGCAAGAAAGTGCGAAAAATTATTCGTTAGGGCCAGCTG
GATTCCAAGATGTAATGGCGCAAACGACATCGAGCATATTCGCAATGGACTCCTATGCAAAATTAATTCAAAATCAGCAA
GAGACTGATTTGAGTAAAATAAGTTCGATTAATAGTGAGTTTAAAGGAAATATGATGCAGCACCAACGAGATGCAAAAAT
TAACGCGGCGTATTGGTTAGATCATATGAAGCCGCAAATTATGAAAACAGATCAAAATATTATTAATTACAATAATACTT
TTCAAGCGTATTATAATAGCATGCTAATTGCGATTGATCAAAAAGATAGCGTAAAGTTAAAAGCGGATTTAGAAAAATTG
TATGCGGATATTGTAAAGAATCAAAATGAGGTAAATGTATTATTAGGAGATTTGAAAGCTTTTCGCGATAGAATGGCGAA
AGACACAAATAGTTTTAAAGAGGATACAAATCAATTAACCTCGATTTTGGCAAGTACGAATGCTGGTATCCCCGCTCTAG
AGCAACAAATCAATACATATAATGATTCAATTAAAAAGAGTAATGATATGGTCATTGCTGGTGGCGTACTTTGCGTAGCG
TTAATAACATGCCTTGCTGGTGGACCGATGATTGCCGTCGCGAAAAAAGATATCGCAAATGCAGAACGGGAAATCGCCAA
TTTAAAGGATAGAATTTCTGGCGCACAAGCAGAAGTGGCAATATTGACAGATGTAAAAAATAAAACAACAAACATGACTG
AAACGATTGATGCAGCAATTACAGCGCTGCAAAACATATCAAATCAATGGTATACAGTAGGGGCAAAATATAATAATTTA
CTACAAAACGTAAAAGGAATCAGCCCTGAAGAGTTTACCTTCATAAAAGAAGATTTACATACAGCGAAAGATAGCTGGAA
AGATGTAAAAGATTATACAGAAAAATTACATGAAGGCGTGGCGAAGTAA

Upstream 100 bases:

>100_bases
AGCGAAAGCAAAGAAGTTAGGTGGGGGGCGGGCTGCCCATAAAAGTCCGATTGGTGAGGGCTGATTAAAGTTTCACTTTA
TACCCTTATAAAGAAAATAG

Downstream 100 bases:

>100_bases
ACAGTGGACTAGTTCCGCTGTTTACTTTTTATCCTGTTTTTTGTGAGAAGTGGACTTGTAATTTGATAGATAAATTTCTG
ATCAAGCTTTTTATATTTAA

Product: enterotoxin C

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKSMQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQ
ETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKL
YADIVKNQNEVNVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVA
LITCLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNL
LQNVKGISPEEFTFIKEDLHTAKDSWKDVKDYTEKLHEGVAK

Sequences:

>Translated_362_residues
MKSMQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQ
ETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKL
YADIVKNQNEVNVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVA
LITCLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNL
LQNVKGISPEEFTFIKEDLHTAKDSWKDVKDYTEKLHEGVAK
>Mature_362_residues
MKSMQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQ
ETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKL
YADIVKNQNEVNVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVA
LITCLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNL
LQNVKGISPEEFTFIKEDLHTAKDSWKDVKDYTEKLHEGVAK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 40340; Mature: 40340

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKTLQESAKNYSLGPAGFQDVMA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QTTSSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHH
MKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVNVLLGDLKA
HHCCCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
LITCLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
TALQNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLHTAKDSWKDVKDYTEKLHEGV
HHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AK
CC
>Mature Secondary Structure
MKSMQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKTLQESAKNYSLGPAGFQDVMA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QTTSSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHH
MKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVNVLLGDLKA
HHCCCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
LITCLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
TALQNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLHTAKDSWKDVKDYTEKLHEGV
HHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]