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The map label for this gene is pyrH [H]

Identifier: 118477269

GI number: 118477269

Start: 1721483

End: 1722226

Strand: Reverse

Name: pyrH [H]

Synonym: BALH_1580

Alternate gene names: 118477269

Gene position: 1722226-1721483 (Counterclockwise)

Preceding gene: 118477278

Following gene: 118477262

Centisome position: 32.76

GC content: 38.71

Gene sequence:

>744_bases
ATGAGACCATATAAACGTGTCTTAATTAAATTAAGCGGCGGTGCACTTGCCGATCAAACCGGAAATAGCTTTAACTCCAA
ACGATTAGAACATATCGCAAATGAGATTTTATCCATCGTTGATTTAGGTATTGAAGTATCTATCGTCATCGGAGGCGGGA
ACATTTTCAGAGGTCATTTAGCTGAAGAATGGGGCATTGATCGTGTAGAAGCTGATAATATTGGTACATTAGGTACCATC
ATTAATAGCTTAATGCTACGCGGCGTTTTAACAAGCAAAACAAATAAAGAAGTTCGCGTTATGACTTCCATCCCGTTTAA
TGCTGTAGCTGAACCATATATTCGCTTGCGTGCAGTCCATCATTTAGATAACGGTTATATCGTTATTTTTGGAGGCGGTA
ATGGGCAACCGTTCGTTACGACAGATTACCCTAGTGTTCAAAGAGCCATTGAAATGAATAGTGACGCAATATTAGTCGCC
AAACAAGGAGTAGATGGCGTCTTTACTAGTGATCCAAAACATAATAAAGCAGCAAAAATGTACAAAAAACTAAACTATAA
CGATATTGTTAGGCAAAACATACAAGTAATGGATCAAGCCGCTTTACTACTTGCCCGTGATTATAATTTGCCAGCACACG
TCTTTAACTTCGATGAGCCTGGAGTGATGAGACGAATTTGTTTAGGAGAGCATGTAGGAACATTGATTAATGATGACGCT
TCTTTACTTGCGCATGAGAAATAA

Upstream 100 bases:

>100_bases
TTCGCCTTATCTTCTTCTTTTCTTTTTCATTTTCTTAAAAAGGAACAAGGGCATTTGCCTTTGTTCCTTTTTTATTGCGA
TTTATATAGGGGGAATTGTT

Downstream 100 bases:

>100_bases
TTATTTCTCATTTTAAAAGGGTGTCTATAAAAGACACCCTTTTTCCATTAACCTTTATAAATAAAAATCCACCATCCCAG
CAAATTTCTCCTTACAACGC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKAAKMYKKLNYNDIVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLAHEK

Sequences:

>Translated_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKAAKMYKKLNYNDIVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLAHEK
>Mature_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKAAKMYKKLNYNDIVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLAHEK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=43.4042553191489, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27207; Mature: 27207

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVH
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKAAKM
ECCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHH
YKKLNYNDIVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCH
SLLAHEK
HHHCCCC
>Mature Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVH
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKAAKM
ECCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHH
YKKLNYNDIVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCH
SLLAHEK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA