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The map label for this gene is yciC [H]

Identifier: 118477240

GI number: 118477240

Start: 1690594

End: 1692177

Strand: Reverse

Name: yciC [H]

Synonym: BALH_1547

Alternate gene names: 118477240

Gene position: 1692177-1690594 (Counterclockwise)

Preceding gene: 118477248

Following gene: 118477239

Centisome position: 32.19

GC content: 32.32

Gene sequence:

>1584_bases
ATGAGTGAAGAAACGATTATCCCTAGTAAAATAAAAGGTATTGCTTCAAAAATAATACTTAAAAAGAGTGTGTTCACATT
CAACCATACTTGCGGCATACTTTTGTGCAAATTTGCTAGGCTTGTAAAATCTACAAAAAATAATAAAAAGAGAAAAATAA
CAATAAGCACTATGCCTGCTAATTCTTTTGAAACTCTATTAAAAACCAACCTTCTCGCCTCCATTTTATTTATATGTAAA
CATGTGCTTGTCCAAATGCATCTACTACTACAACACAAATGTTATAGTCTATTCCTATTCTTAAATCGTAATCATTATGA
TTTATTATTGATTTTTCCTTTTCAATCATTTAACATAAAACGTAATCATTACGATTTAAAGGAGAGAAAGAATTTCATGA
AAAAAATACCTATCACTGTATTAAGTGGGTTTTTAGGATCCGGAAAAACTACATTACTACATCATATTTTAACTAATAAG
AACAACTTAAAAGTAGCTGTTATCGTTAATGATATGAGCGAAGTAAACATTGATGCCTCCCTTATAAAAAAAGGTGGTTT
TTCACGTACGGAGGAAAAACTAGTAGAAATTCAAAATGGCTGTATTTGTTGTACACTACGAGAAGATTTAATAATAGAAG
TGAATCGCCTTATTGAAAACGGTGATATTGACTATATAGTGATTGAATCTTCCGGTATAAGTGAGCCAATTCCAGTTGCC
CAAACATTTACTTATACTGACGACGCTCTTAACATTGATTTAACGAAAAATTGTCGCCTCGATACGATGGTTACAGTTGT
AGATGCAAATAGATTTTGGGATGATTTTGCAGATGGAGAAAGTTTATTAGATCGCAAACAAGCAATCAATGAAAATGATA
CTCGGGAAGTTATTGATTTATTAATAGATCAAATTGAGTTTGCAAATGTAATTATTCTTAATAAGATAGATCTACTAGAA
AAAGAAGATGTGATTGAACTTCATCAACTGCTACAGAAATTAAATCCTAATGCAAAAATTATTGAATCTTCCTTTAGCAA
CGTACCACTGCAAGAAATTTTAAATACAAATGTATTCAATTATGAGGAAGCCAGTCAATCGGCGGGCTGGATACAAGAAT
TAAATAGTGAACATCATACACCCGAAACGGAAGAATACGGTATCAATTCCTTTGTATACCGTCGTAAATACCCTTTCCAT
CCTGAACGCCTTATGAATTGGCTAGAAAAATGGCCTGTAGATGTCGTAAGAGCAAAAGGCTTTTTCTGGCTCGCATCTCG
TAATAATATGATAGGTCTTCTATCTCAAGCAGGTTCCTCTATTACAATTCAAGGAGCCGGTGAATGGATAGCAGCATTAC
CTGAAACTGAAAGAAATCAAATGATCATAGAAGAGCCAGAAGTATTGAAAAACTGGGATAAACAATATGGAGATCGAATA
ACTGAACTCGTATTTATTGGAATTGATATGAACCGTTCTTTAATTGAACAATCATTAGATGATTGTCTATTAACAGAAAA
AGAAATGACACAAAACTGGAATACATTCATTGATCCTATTCCAGCTTTTACTTACACTTCATAA

Upstream 100 bases:

>100_bases
CATTGGAAAAAGAATTCCTACAAATACTGCTGGAATCATTGCAACAATTGGAGATCTCAGCATTACTTTTTGAATCATAT
CTTCTGTCACAAACACTTGA

Downstream 100 bases:

>100_bases
TTCAAAATAGAGAGGCTTCCGTTTACGGAAGCCTTTCTATTTTATCGTTCTCTTATTTAACAAACTTCTTTCATTTGAAT
AATAACTTTACATTAAGTAA

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSEETIIPSKIKGIASKIILKKSVFTFNHTCGILLCKFARLVKSTKNNKKRKITISTMPANSFETLLKTNLLASILFICK
HVLVQMHLLLQHKCYSLFLFLNRNHYDLLLIFPFQSFNIKRNHYDLKERKNFMKKIPITVLSGFLGSGKTTLLHHILTNK
NNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLIIEVNRLIENGDIDYIVIESSGISEPIPVA
QTFTYTDDALNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDLLIDQIEFANVIILNKIDLLE
KEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQELNSEHHTPETEEYGINSFVYRRKYPFH
PERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRI
TELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS

Sequences:

>Translated_527_residues
MSEETIIPSKIKGIASKIILKKSVFTFNHTCGILLCKFARLVKSTKNNKKRKITISTMPANSFETLLKTNLLASILFICK
HVLVQMHLLLQHKCYSLFLFLNRNHYDLLLIFPFQSFNIKRNHYDLKERKNFMKKIPITVLSGFLGSGKTTLLHHILTNK
NNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLIIEVNRLIENGDIDYIVIESSGISEPIPVA
QTFTYTDDALNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDLLIDQIEFANVIILNKIDLLE
KEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQELNSEHHTPETEEYGINSFVYRRKYPFH
PERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRI
TELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
>Mature_526_residues
SEETIIPSKIKGIASKIILKKSVFTFNHTCGILLCKFARLVKSTKNNKKRKITISTMPANSFETLLKTNLLASILFICKH
VLVQMHLLLQHKCYSLFLFLNRNHYDLLLIFPFQSFNIKRNHYDLKERKNFMKKIPITVLSGFLGSGKTTLLHHILTNKN
NLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLIIEVNRLIENGDIDYIVIESSGISEPIPVAQ
TFTYTDDALNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDLLIDQIEFANVIILNKIDLLEK
EDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQELNSEHHTPETEEYGINSFVYRRKYPFHP
ERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRIT
ELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=268, Percent_Identity=30.9701492537313, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI126722884, Length=276, Percent_Identity=30.0724637681159, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI146231952, Length=276, Percent_Identity=30.0724637681159, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI148727351, Length=276, Percent_Identity=29.7101449275362, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI223941779, Length=232, Percent_Identity=31.0344827586207, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI223941776, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI119120938, Length=153, Percent_Identity=34.640522875817, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI87082430, Length=369, Percent_Identity=27.3712737127371, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788499, Length=211, Percent_Identity=31.7535545023697, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=235, Percent_Identity=30.2127659574468, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 60572; Mature: 60440

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEETIIPSKIKGIASKIILKKSVFTFNHTCGILLCKFARLVKSTKNNKKRKITISTMPA
CCCCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
NSFETLLKTNLLASILFICKHVLVQMHLLLQHKCYSLFLFLNRNHYDLLLIFPFQSFNIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCC
RNHYDLKERKNFMKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDAS
CCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHH
LIKKGGFSRTEEKLVEIQNGCICCTLREDLIIEVNRLIENGDIDYIVIESSGISEPIPVA
HHHCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
QTFTYTDDALNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDL
EEEEECCCCEEEEECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
LIDQIEFANVIILNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFN
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCC
YEEASQSAGWIQELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKG
CHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHCCHHHEEECC
FFWLASRNNMIGLLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRI
EEEEECCCCEEEEHCCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHE
TELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
EEEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
SEETIIPSKIKGIASKIILKKSVFTFNHTCGILLCKFARLVKSTKNNKKRKITISTMPA
CCCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
NSFETLLKTNLLASILFICKHVLVQMHLLLQHKCYSLFLFLNRNHYDLLLIFPFQSFNIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCC
RNHYDLKERKNFMKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDAS
CCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHH
LIKKGGFSRTEEKLVEIQNGCICCTLREDLIIEVNRLIENGDIDYIVIESSGISEPIPVA
HHHCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
QTFTYTDDALNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDL
EEEEECCCCEEEEECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
LIDQIEFANVIILNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFN
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCC
YEEASQSAGWIQELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKG
CHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHCCHHHEEECC
FFWLASRNNMIGLLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRI
EEEEECCCCEEEEHCCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHE
TELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
EEEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]