Click here to switch to the map view.

The map label for this gene is gloA [H]

Identifier: 118476292

GI number: 118476292

Start: 633215

End: 633601

Strand: Direct

Name: gloA [H]

Synonym: BALH_0546

Alternate gene names: 118476292

Gene position: 633215-633601 (Clockwise)

Preceding gene: 118476288

Following gene: 118476293

Centisome position: 12.04

GC content: 36.18

Gene sequence:

>387_bases
ATGAATATAAGTAGAGTGCACCACGTTGCAATTATTTGTTCGAATTATGAAGTGTCAAAGGATTTTTATACTAGGATATT
GGGTTTTAAAGCGATAAATGAAGTATATAGAAAGGAAAGAGATTCTTATAAGTTAGATTTATGTGTAGGAAAAGAGTATC
AAATTGAATTATTTTCATTTCCGAATCCTCCGAAGCGTCCGAGCTTCCCAGAAGCGGCTGGACTTAGGCATTTAGCATTT
GCTGTTACAAATATAGAAGAAGCCGTGCAACATTTAAGTCAATGTGGCGTTGAAACTGAGGCGATACGTATTGATGAGAT
AACCGGGAAAAAATTTGTTTTTTTCCAAGACCCTGACGGTCTACCGTTAGAATTGTATGAGGTTTGA

Upstream 100 bases:

>100_bases
AAATTTCATAGTAAGCCCCCTAAAAGAGATATTCTGCTATATATGTTTTTCATTTCAAGGGAGAATATGCATCTTTGGTA
AAGAAAGGAATAAAGAAATC

Downstream 100 bases:

>100_bases
AATTGGTGAATTTTATATAGGGTTGCTTTTGAGTAAATGAAGAAACTAAAGTGAAACTTCTTTTTAAAAGGAGGTGTAAC
TTTAGCTAAGAAAGCTAAAG

Product: lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MNISRVHHVAIICSNYEVSKDFYTRILGFKAINEVYRKERDSYKLDLCVGKEYQIELFSFPNPPKRPSFPEAAGLRHLAF
AVTNIEEAVQHLSQCGVETEAIRIDEITGKKFVFFQDPDGLPLELYEV

Sequences:

>Translated_128_residues
MNISRVHHVAIICSNYEVSKDFYTRILGFKAINEVYRKERDSYKLDLCVGKEYQIELFSFPNPPKRPSFPEAAGLRHLAF
AVTNIEEAVQHLSQCGVETEAIRIDEITGKKFVFFQDPDGLPLELYEV
>Mature_128_residues
MNISRVHHVAIICSNYEVSKDFYTRILGFKAINEVYRKERDSYKLDLCVGKEYQIELFSFPNPPKRPSFPEAAGLRHLAF
AVTNIEEAVQHLSQCGVETEAIRIDEITGKKFVFFQDPDGLPLELYEV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081697, Length=127, Percent_Identity=59.8425196850394, Blast_Score=159, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14741; Mature: 14741

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISRVHHVAIICSNYEVSKDFYTRILGFKAINEVYRKERDSYKLDLCVGKEYQIELFSF
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
PNPPKRPSFPEAAGLRHLAFAVTNIEEAVQHLSQCGVETEAIRIDEITGKKFVFFQDPDG
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCC
LPLELYEV
CCEEEEEC
>Mature Secondary Structure
MNISRVHHVAIICSNYEVSKDFYTRILGFKAINEVYRKERDSYKLDLCVGKEYQIELFSF
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
PNPPKRPSFPEAAGLRHLAFAVTNIEEAVQHLSQCGVETEAIRIDEITGKKFVFFQDPDG
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCC
LPLELYEV
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]