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The map label for this gene is pbpX [H]

Identifier: 118476190

GI number: 118476190

Start: 497719

End: 498984

Strand: Direct

Name: pbpX [H]

Synonym: BALH_0439

Alternate gene names: 118476190

Gene position: 497719-498984 (Clockwise)

Preceding gene: 118476189

Following gene: 118476191

Centisome position: 9.47

GC content: 34.36

Gene sequence:

>1266_bases
TTGGTGAATAAGGGGAAAAAAGCAATCATGGATCAGGAAAAAAATAATGCGAATGGGAAATCACGTCGGCCGATTGTATA
CATAAAAAGAACAATCATTTTCGTCTTACTATTTTCACTTGTATATTTCATGTATACAAAAATTGTTACGCATAATAAGA
AAGAAGAAACTTTAAAAGCGGCAGAAATGAAGAAACAAGAAGAGCTAAAAAAGAAAGAAGAAAAAAAGAAGCAAGAAGCA
AAAAAACAAAAAGAGCAGAAAGAACAAGTGAAGCAAGCACAAGCTGTGGAAAAGCCTGCTGAGGGACCACCTCAAGAAGT
TAATGAAAACGCTCAATTAGATCAATATTTACAAAATACAGGATTTAGCGGGACAGCGGTTATTGTGAAGAACGGAAAAG
TTCTTTTGAATAAAGGATATGGTATGGCGAATAAAGAGAAACAAGTACCGAATAATTCAGAGACAACTTTTTATATTGGT
TCTATTTCAAAGGCGTTTGTAGCGACTGCTATTATGCAATTAAAAGATCAAAATAAGTTAAATGTAGAGGATACGATTGC
GAAGTATATTCCAGATTTCCCTCAAGGTAACGGTATTCAGTTAAAACATTTATTAACACATACATCAGGAATTCCGGAGT
ACGAGCAGGGAACAGAGGATATTTCTCATGAAGAATTGATAAAACGAATAGGAAAGCAAAAGCGCATTGGAAGTCCAGGA
GAGAAATGGAAGTATTCCGATTCTAACTATTCGATACTCGCCTATATTGCTGAGAAGGTAAGCGGACAACCGTTAGAAGA
GTATATTAAACAACATATTTTTGCTACTGCTGGTATGAAACATTCTGGTTTTGGTAGAGAGCTAGAACAAACAAGATTTC
CATCGACAGGTTATAAAATAGTAAATAACAATATGACAACACCTAATATTCCAAGTATGTCACAACTATATGGTTGTGGT
GATATATATACAAGTGCACATGATTTGTATTTATTTAATGAAGCGCTCTTCTCTGGAAAGTTAATTTCAAAAGAAAGCTA
CGATCAAATGTTTACAGGCGGAAAAAAAGATTACGGGTTTGGATGGTACGTAGACCCGGGAAGTTATTCGAATCACGGTG
TAATGCCAGGATGGAATTGCTTGAATGGATTTAGTAAAAACGGAAGTGTATATGTCGTTTTATTATCTAACATTCAAAAT
AACATTAAATCGTTTGGTAAAGTGAACAACGATATTTATACGATGTTGCGAAATATTGAAGTGTAA

Upstream 100 bases:

>100_bases
ATAGGTTGGTAATATGTGTAGTGCGTGATAAAGTAGGGATGATATAGAATGTATTATCCATAATCTACTAAAATGAATCT
TTAGTAAAGGTAGTAAATTA

Downstream 100 bases:

>100_bases
GGGACTATCTTTTTAGATAGTCTTTTTTTATGGAGAAAGTGTATCTGCCATTGTTACAATTAAAAATTAAAATACATAAA
AAGATAGATAGAATACCATC

Product: penicillin-binding protein

Products: substituted beta-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVNKGKKAIMDQEKNNANGKSRRPIVYIKRTIIFVLLFSLVYFMYTKIVTHNKKEETLKAAEMKKQEELKKKEEKKKQEA
KKQKEQKEQVKQAQAVEKPAEGPPQEVNENAQLDQYLQNTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIG
SISKAFVATAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPG
EKWKYSDSNYSILAYIAEKVSGQPLEEYIKQHIFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCG
DIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQN
NIKSFGKVNNDIYTMLRNIEV

Sequences:

>Translated_421_residues
MVNKGKKAIMDQEKNNANGKSRRPIVYIKRTIIFVLLFSLVYFMYTKIVTHNKKEETLKAAEMKKQEELKKKEEKKKQEA
KKQKEQKEQVKQAQAVEKPAEGPPQEVNENAQLDQYLQNTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIG
SISKAFVATAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPG
EKWKYSDSNYSILAYIAEKVSGQPLEEYIKQHIFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCG
DIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQN
NIKSFGKVNNDIYTMLRNIEV
>Mature_421_residues
MVNKGKKAIMDQEKNNANGKSRRPIVYIKRTIIFVLLFSLVYFMYTKIVTHNKKEETLKAAEMKKQEELKKKEEKKKQEA
KKQKEQKEQVKQAQAVEKPAEGPPQEVNENAQLDQYLQNTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIG
SISKAFVATAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPG
EKWKYSDSNYSILAYIAEKVSGQPLEEYIKQHIFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCG
DIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQN
NIKSFGKVNNDIYTMLRNIEV

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=313, Percent_Identity=25.2396166134185, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786574, Length=287, Percent_Identity=23.6933797909408, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790593, Length=184, Percent_Identity=25.5434782608696, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=402, Percent_Identity=21.6417910447761, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 47634; Mature: 47634

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKGKKAIMDQEKNNANGKSRRPIVYIKRTIIFVLLFSLVYFMYTKIVTHNKKEETLKA
CCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AEMKKQEELKKKEEKKKQEAKKQKEQKEQVKQAQAVEKPAEGPPQEVNENAQLDQYLQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHC
GFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVATAIMQLKDQNKL
CCCCEEEEEECCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCC
NVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPG
CHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCC
EKWKYSDSNYSILAYIAEKVSGQPLEEYIKQHIFATAGMKHSGFGRELEQTRFPSTGYKI
CCCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCEE
VNNNMTTPNIPSMSQLYGCGDIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGF
ECCCCCCCCCCCHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCC
GWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKVNNDIYTMLRNIE
EEEECCCCCCCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCC
V
C
>Mature Secondary Structure
MVNKGKKAIMDQEKNNANGKSRRPIVYIKRTIIFVLLFSLVYFMYTKIVTHNKKEETLKA
CCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AEMKKQEELKKKEEKKKQEAKKQKEQKEQVKQAQAVEKPAEGPPQEVNENAQLDQYLQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHC
GFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVATAIMQLKDQNKL
CCCCEEEEEECCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCC
NVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPG
CHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCC
EKWKYSDSNYSILAYIAEKVSGQPLEEYIKQHIFATAGMKHSGFGRELEQTRFPSTGYKI
CCCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCEE
VNNNMTTPNIPSMSQLYGCGDIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGF
ECCCCCCCCCCCHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCC
GWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKVNNDIYTMLRNIE
EEEECCCCCCCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]