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The map label for this gene is fabH [H]

Identifier: 117920011

GI number: 117920011

Start: 1825843

End: 1826970

Strand: Direct

Name: fabH [H]

Synonym: Shewana3_1563

Alternate gene names: 117920011

Gene position: 1825843-1826970 (Clockwise)

Preceding gene: 117920010

Following gene: 117920012

Centisome position: 36.72

GC content: 49.56

Gene sequence:

>1128_bases
ATGAAACAGGTCGTTATTTCTGGCAGCGGTTTATTTACGCCGCCACACAGTATTTCTAATGAAGCTTTGGTGGAGAGCTT
CAACGCCTATGTGGATATGTTTAACCTTGAAAATGCAGGGTTAATTGAGCAGGGCCATGTTGAGCCGCTGTCTTATTCCT
CCAGTGAGTTTATCGAGAAGGCCTCGGGCATCAAGCACAGATATGTGATGGTTAAAGACGGTATTCTCGATCCTGAAATC
ATGATGCCGCTTATTCCTGAGCGTAGCAGTGACGAGTTATCTATGCAGGCCGAAATTGGGGTTGAGGCGGCAGTGATGGC
GCTCAAGCAAGCGGATGTGAAGGCCGAGCAAATCGATTTAGTGATCGTTGCCTGTGCTTATACGCAGCGCGCTTATCCTG
CGATGGCGATTGAAATCCAGCGCGCACTCGGTACCCGTGGCTATGGCTATGGCTATGATATGCAGGTTGCCTGTTCTTCG
GCCACCTTTGCCATTGTGGCCGCCGCCAATGCGATTGCGACGGGCTCGGCGTCACGGGTGTTAGTGATTAACCCCGAAAT
TTGTTCGGCGCAGGTTAACTACCGTGACCGTGACAGTCACTTTATCTTCGGGGATGTAGCGACTGCTATGGTGCTTGAAG
AGCAAAGCCTAGTGGCCGCCAATAAGGGCTTTAACATTGTTTCAAGCCGTTGTTTTACTGACTACTCGAACAATATTCGC
AGTAATTTCGGCTTTTTAAATCGCTGCGACCCAAGCTCGGCGCATCAGGCGGATAAGTTATTCCACCAACAGGGACGCAA
AGTCTTTAAAGAGCTGTTGCCGATGATTTATCAGCATTTAGACGAGCATCTGGCCGAGCAATCCCTCACACCACAGTCCT
TTAAACGTTTGTGGTTGCATCAAGCCAACATCAACATGAACCAATTCGTGGTGAAAAAACTGCTAGGGGATGAGGTAACG
CCAGAGCAAGCACCTGTGGTGCTCGACGAGTATGCCAATACCGCCTCCGCTGGCTCTGTGATTGCCTTCCATAAATATTC
CGCTGACTTTAACGCGGGCGATTTAGGGCTATTAAGTTCCTTTGGCGCGGGTTACTCCATCGGTAGCGTGATTTTGCAAA
AACGCTAA

Upstream 100 bases:

>100_bases
AGCAGCAACAGGCGCAGGCTGAACACGCATTGGCCGCCGTGCCAACACAGAATAATGCGACGTCTGCTCACCTTACAACA
AGCACCCGTTCGGAGCACCT

Downstream 100 bases:

>100_bases
ATCGACTCAGGCCCCATTGCAAGCAATGGGGCCTGAGCTTTTATATCAGCACATTGATTAAACGGCTCGATGCGGTACCT
TAGCCGAAAATGCCTTTAAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKQVVISGSGLFTPPHSISNEALVESFNAYVDMFNLENAGLIEQGHVEPLSYSSSEFIEKASGIKHRYVMVKDGILDPEI
MMPLIPERSSDELSMQAEIGVEAAVMALKQADVKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYGYDMQVACSS
ATFAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATAMVLEEQSLVAANKGFNIVSSRCFTDYSNNIR
SNFGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQSLTPQSFKRLWLHQANINMNQFVVKKLLGDEVT
PEQAPVVLDEYANTASAGSVIAFHKYSADFNAGDLGLLSSFGAGYSIGSVILQKR

Sequences:

>Translated_375_residues
MKQVVISGSGLFTPPHSISNEALVESFNAYVDMFNLENAGLIEQGHVEPLSYSSSEFIEKASGIKHRYVMVKDGILDPEI
MMPLIPERSSDELSMQAEIGVEAAVMALKQADVKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYGYDMQVACSS
ATFAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATAMVLEEQSLVAANKGFNIVSSRCFTDYSNNIR
SNFGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQSLTPQSFKRLWLHQANINMNQFVVKKLLGDEVT
PEQAPVVLDEYANTASAGSVIAFHKYSADFNAGDLGLLSSFGAGYSIGSVILQKR
>Mature_375_residues
MKQVVISGSGLFTPPHSISNEALVESFNAYVDMFNLENAGLIEQGHVEPLSYSSSEFIEKASGIKHRYVMVKDGILDPEI
MMPLIPERSSDELSMQAEIGVEAAVMALKQADVKAEQIDLVIVACAYTQRAYPAMAIEIQRALGTRGYGYGYDMQVACSS
ATFAIVAAANAIATGSASRVLVINPEICSAQVNYRDRDSHFIFGDVATAMVLEEQSLVAANKGFNIVSSRCFTDYSNNIR
SNFGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQSLTPQSFKRLWLHQANINMNQFVVKKLLGDEVT
PEQAPVVLDEYANTASAGSVIAFHKYSADFNAGDLGLLSSFGAGYSIGSVILQKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=336, Percent_Identity=27.3809523809524, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41084; Mature: 41084

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVVISGSGLFTPPHSISNEALVESFNAYVDMFNLENAGLIEQGHVEPLSYSSSEFIEK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ASGIKHRYVMVKDGILDPEIMMPLIPERSSDELSMQAEIGVEAAVMALKQADVKAEQIDL
HCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHHCCCHHHEEE
VIVACAYTQRAYPAMAIEIQRALGTRGYGYGYDMQVACSSATFAIVAAANAIATGSASRV
EEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEHHHHCCCCCCEE
LVINPEICSAQVNYRDRDSHFIFGDVATAMVLEEQSLVAANKGFNIVSSRCFTDYSNNIR
EEECCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
SNFGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQSLTPQSFKRLWLH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QANINMNQFVVKKLLGDEVTPEQAPVVLDEYANTASAGSVIAFHKYSADFNAGDLGLLSS
HCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHH
FGAGYSIGSVILQKR
CCCCCCHHHHHEECC
>Mature Secondary Structure
MKQVVISGSGLFTPPHSISNEALVESFNAYVDMFNLENAGLIEQGHVEPLSYSSSEFIEK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ASGIKHRYVMVKDGILDPEIMMPLIPERSSDELSMQAEIGVEAAVMALKQADVKAEQIDL
HCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHHCCCHHHEEE
VIVACAYTQRAYPAMAIEIQRALGTRGYGYGYDMQVACSSATFAIVAAANAIATGSASRV
EEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEHHHHCCCCCCEE
LVINPEICSAQVNYRDRDSHFIFGDVATAMVLEEQSLVAANKGFNIVSSRCFTDYSNNIR
EEECCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
SNFGFLNRCDPSSAHQADKLFHQQGRKVFKELLPMIYQHLDEHLAEQSLTPQSFKRLWLH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QANINMNQFVVKKLLGDEVTPEQAPVVLDEYANTASAGSVIAFHKYSADFNAGDLGLLSS
HCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHH
FGAGYSIGSVILQKR
CCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA