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The map label for this gene is mrdB [H]

Identifier: 117919443

GI number: 117919443

Start: 1164227

End: 1165330

Strand: Reverse

Name: mrdB [H]

Synonym: Shewana3_0994

Alternate gene names: 117919443

Gene position: 1165330-1164227 (Counterclockwise)

Preceding gene: 117919444

Following gene: 117919442

Centisome position: 23.44

GC content: 49.55

Gene sequence:

>1104_bases
ATGAGTGCCCAACCACGTCAAAATATCTGGCAACGAATGCATATCGACTTGCCCTTACTGCTCGGTCTGTTTGCCGTCAT
GGGCTTTGGCCTGTTTGTTATTTACTCCGCCAGCGGTGAAGACCTTGGCATGATGGAGCGCCAACTGTTTAGGATGTTTT
TATCCCTAGGCATTATGTTTACCATGGCGCAGATCAATCCCGAGGCGCTAAAACGCTGGGCTTTACCGATTTACCTTGCG
GGGATTGTACTGCTGCTTGGGGTGCATTTTTTTGGGGAAATAAATAAAGGCGCGCAGCGCTGGTTGAACTTAGGCTTTAT
GGAGTTCCAGCCATCGGAACTGATTAAACTCGCCTTCCCCATCACTATGGCGTGGTATATCAGTAAGTTCCCTCTGCCGC
CGAAGAAACGTTACCTTGCAGGTGCGGCGGTGATTTTGTTAGTCCCGACGCTGCTAATTGCCAAGCAACCAGACTTAGGT
ACCTCAATTTTGGTTGCGGCATCGGGCATTTTCGTGCTGTTTTTATCGGGCATGAGCTGGGCGATTGTGGGCGGTTTTAT
TGCCGCTGTATTAGCCTTCTTGCCGATCCTCTGGTACTTCCTGATGCACGATTACCAAAGAACCCGCGTGATGACCCTAC
TCGATCCGGAGAAGGATCCGCTAGGCGCTGGTTACCACATCATTCAATCAAAAATCGCCATTGGCTCCGGCGGCCTCTGG
GGCAAAGGTTGGCTCGATGGCACCCAATCCCAATTAGAATTTATCCCCGAACGTCACACCGACTTCATCTTTGCGGTGAT
CGGTGAAGAGTTTGGCCTGATAGGCAGTATTATCCTGCTCCTGATGTATCTGTATATCATCGGACGCGGCTTAGTCATCG
CCTCTCGCGCGCAAACCAGCTTCGCCCGGCTCCTTGCAGGCAGTATCACATTGACTTTCTTCGTTTATGTTTTTGTGAAT
ATTGGTATGGTTTCAGGTATCCTGCCTGTGGTGGGTGTACCTTTACCCCTTGTCAGTTATGGTGGTACTTCCATGCTGAC
ATTGATGACAGGGTTTGGCATTCTTATGAGCATTCATACCCATAGACGTTTTGTAGATAGATAA

Upstream 100 bases:

>100_bases
TGGTAATGGAAAACGCCGGCTGGGGTGGCGCAAACGCAGGCCCAGTCGCCCGCGCTATGCTCGATGAATACATGCTAAGA
GACACTTGGAAACCAACGCC

Downstream 100 bases:

>100_bases
TTTTTAGGGACTTTTTAATGCCTATTCTTCGAGCTTGTTTGGCTCCACTGGCAGTACTTTGCCTCAGTTCATATCTCCTT
GGTTGCTCGACGGCAAACGA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSAQPRQNIWQRMHIDLPLLLGLFAVMGFGLFVIYSASGEDLGMMERQLFRMFLSLGIMFTMAQINPEALKRWALPIYLA
GIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLG
TSILVAASGIFVLFLSGMSWAIVGGFIAAVLAFLPILWYFLMHDYQRTRVMTLLDPEKDPLGAGYHIIQSKIAIGSGGLW
GKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSIILLLMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFVN
IGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR

Sequences:

>Translated_367_residues
MSAQPRQNIWQRMHIDLPLLLGLFAVMGFGLFVIYSASGEDLGMMERQLFRMFLSLGIMFTMAQINPEALKRWALPIYLA
GIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLG
TSILVAASGIFVLFLSGMSWAIVGGFIAAVLAFLPILWYFLMHDYQRTRVMTLLDPEKDPLGAGYHIIQSKIAIGSGGLW
GKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSIILLLMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFVN
IGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR
>Mature_366_residues
SAQPRQNIWQRMHIDLPLLLGLFAVMGFGLFVIYSASGEDLGMMERQLFRMFLSLGIMFTMAQINPEALKRWALPIYLAG
IVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLGT
SILVAASGIFVLFLSGMSWAIVGGFIAAVLAFLPILWYFLMHDYQRTRVMTLLDPEKDPLGAGYHIIQSKIAIGSGGLWG
KGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSIILLLMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFVNI
GMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=368, Percent_Identity=60.8695652173913, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786277, Length=306, Percent_Identity=37.2549019607843, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40731; Mature: 40599

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPRQNIWQRMHIDLPLLLGLFAVMGFGLFVIYSASGEDLGMMERQLFRMFLSLGIMF
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TMAQINPEALKRWALPIYLAGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHHH
ITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMSW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHH
AIVGGFIAAVLAFLPILWYFLMHDYQRTRVMTLLDPEKDPLGAGYHIIQSKIAIGSGGLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCCC
GKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSIILLLMYLYIIGRGLVIASRAQTS
CCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
FARLLAGSITLTFFVYVFVNIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
HRRFVDR
HHHHCCC
>Mature Secondary Structure 
SAQPRQNIWQRMHIDLPLLLGLFAVMGFGLFVIYSASGEDLGMMERQLFRMFLSLGIMF
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TMAQINPEALKRWALPIYLAGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHHH
ITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMSW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHH
AIVGGFIAAVLAFLPILWYFLMHDYQRTRVMTLLDPEKDPLGAGYHIIQSKIAIGSGGLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCCC
GKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSIILLLMYLYIIGRGLVIASRAQTS
CCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
FARLLAGSITLTFFVYVFVNIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
HRRFVDR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]