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The map label for this gene is nqrA [H]

Identifier: 117919387

GI number: 117919387

Start: 1099135

End: 1100469

Strand: Direct

Name: nqrA [H]

Synonym: Shewana3_0938

Alternate gene names: 117919387

Gene position: 1099135-1100469 (Clockwise)

Preceding gene: 117919386

Following gene: 117919388

Centisome position: 22.11

GC content: 47.49

Gene sequence:

>1335_bases
ATGATTACAATTAAGAAAGGATTGGAACTGCCTATAGCAGGCGGACCAGAGCAAGTTATCCATAATGGCCCAGCCATTAA
ACATGTAGCTACTTTGGGTGAAGAGTATATTGGCTTACGTCCAACGATGAAGATCAAAGTGGGCGACAAAGTTCAAAAAG
GTCAGGTGATTTTCGAAGATAAGAAAAATCCTGGCGTAAAATATACGGCTTTAGCCAGTGGTACTATATTAGACATTAAC
CGGGGCGCCCAGCGTGTGCTGCAGTCTGTTGTTATTCAAGTAGAAGGGAACGAAAGCGTTGCCTTTGCTAAGTATGACGC
CACTGCTCTCGATACGCTAGACTCGCAACTGGTCCGTGACAACCTGATCGAATCAGGCTTATGGACTGCATTGCGTACAC
GTCCTTTCAGCAAAGTGCCTGCCGTAGATTCTTCTGCCGCTGGTATTTTCGTCACCGCGATTGATACGCAACCCCATGCC
GCCGATCCTGTTGTAGTGATCCGTGAGCATAAAGAAGATTTTGCTAATGGTCTTAAGGTCTTAGCAAGACTTACCGAAGG
TAAAGTTTACCTTTGTAAAGCGCCTGGCGCCGATATTCCTGCCGCTAATGCCCAAGTTGAAGAATTTGCCGGTGTTCACC
CTGCGGGTCTTGTTGGTACTCATATCCATTTCCTACTTCCTGCTTCTGCAAAACGTACTGTTTGGCATGTCGGTTACCAA
GATGTAATAGCCATTGGTCAGCTATTTACTACCGGTCAACTGAATACCGAACGTGTGATCGCAATTGCCGGTCCTAAAGC
GGCTAAGCCACGTCTGGTTCGCACTGTTTTAGGTGCAAGCATGACTGAACTGACCGCGGGCGAAACCTTAGACGGTAACG
TACGTGTTGTTTCAGGCTCTGTGCTGAATGGCCGTACTGCTGTAGGTCCTCAAGGATATTTAGGTCGTTACCACGCGCAG
GTGAGTCTGTTAGAAGAAGGCACTGAAAAAGAATTCTTTGGTTGGGTGTTACCAGGCTCAAACAAATACTCTATTACCCG
TGCATTCCTTGGCCACTTAAGCGCTTCTCGTCTGTTCAACATGACAACGAGCACAGGTGGTTCAGACCGCGCTATGGTGC
CAATCGGCAACTACGAGCGTGTAATGCCATTGGATATTCTTCCTACTATGTTGTTGCGTGACCTGATCTCAGGTGACTTT
GACGGTGCTGCCACTTTAGGCGCGTTAGAGTTGGATGAAGAAGATCTCGCACTGTGTACGTTCGTATGTCCAGGCAAATA
TGACTACGGTTCATATCTGCGTGACTGTTTAGATACGATCGAGAGGGAAGGCTAA

Upstream 100 bases:

>100_bases
AAATCTGCGCTAGCTCAATGCAGTAGGTTTTGTTTAAAACCTCAGTATTTAGCAGGAACGCGGCGCATTGTCTTTCCTTC
AAAACGTAGTGCTTGTGGAT

Downstream 100 bases:

>100_bases
TGAGCTTGAAAGATTTTTTCGAACGTATTGAACCCGACTTTGAAAAAGGCGGTAAATACGAAAAGTTTTATGCCCTCTTC
GAAGCGGCATACACCATTTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVAFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVIAIAGPKAAKPRLVRTVLGASMTELTAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKEFFGWVLPGSNKYSITRAFLGHLSASRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG

Sequences:

>Translated_444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVAFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVIAIAGPKAAKPRLVRTVLGASMTELTAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKEFFGWVLPGSNKYSITRAFLGHLSASRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG
>Mature_444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVAFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVIAIAGPKAAKPRLVRTVLGASMTELTAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKEFFGWVLPGSNKYSITRAFLGHLSASRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 47661; Mature: 47661

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEC
KKNPGVKYTALASGTILDINRGAQRVLQSVVIQVEGNESVAFAKYDATALDTLDSQLVRD
CCCCCEEEEEEECCEEEECCHHHHHHHHHHEEEEECCCEEEEEECCCHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHAADPVVVIREHKEDFANGLKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHH
LARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHCEEEEEECCCCCCEEEECCHH
DVIAIGQLFTTGQLNTERVIAIAGPKAAKPRLVRTVLGASMTELTAGETLDGNVRVVSGS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEEEEECC
VLNGRTAVGPQGYLGRYHAQVSLLEEGTEKEFFGWVLPGSNKYSITRAFLGHLSASRLFN
EECCCCCCCCCCCCHHHHHEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDFDGAATLGALELDEEDLALCT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRDCLDTIEREG
EECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEC
KKNPGVKYTALASGTILDINRGAQRVLQSVVIQVEGNESVAFAKYDATALDTLDSQLVRD
CCCCCEEEEEEECCEEEECCHHHHHHHHHHEEEEECCCEEEEEECCCHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHAADPVVVIREHKEDFANGLKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHH
LARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHCEEEEEECCCCCCEEEECCHH
DVIAIGQLFTTGQLNTERVIAIAGPKAAKPRLVRTVLGASMTELTAGETLDGNVRVVSGS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEEEEECC
VLNGRTAVGPQGYLGRYHAQVSLLEEGTEKEFFGWVLPGSNKYSITRAFLGHLSASRLFN
EECCCCCCCCCCCCHHHHHEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDFDGAATLGALELDEEDLALCT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRDCLDTIEREG
EECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA