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The map label for this gene is hlyB [H]

Identifier: 117919372

GI number: 117919372

Start: 1077891

End: 1079522

Strand: Reverse

Name: hlyB [H]

Synonym: Shewana3_0923

Alternate gene names: 117919372

Gene position: 1079522-1077891 (Counterclockwise)

Preceding gene: 117919373

Following gene: 117919367

Centisome position: 21.71

GC content: 49.69

Gene sequence:

>1632_bases
ATGTTTAATAGCATTAGAGTCAAGTTTTCGCTGATGTTTGCCATTATGGCCACAGCCTTAATTGTGATGGCCGTGACGGA
TGCGATGCAGAACCGCACCACCCTCAAGCAAATGCAGGAGTTTAGCCAACGATTTAATCCGGCGATTTCGGCTATCCTCA
ACGCCGACCGCGATCTCTATCAGGCCCAATTGAGTGAAGAAGTACTGCTTAGGCCCGAGCTCAGCAGCGAGAACCGCAAG
AGTGAGATAGACAACTGGCAGGAAAACGTCGACCAAGCGCGCGATCGCATGGGGGAATTTAAAAATTATCTGCAAGACCA
TTTAGAAGTTATCAAGTCCACCAGCGGTTTTGAGGCGCAATTTTCACTCTGGTATCAAGCCTCATCGGAAGTGATCAATG
CTGTGAAAAACAATGACTTTGAACTGGCAAGACAACTCCATGAAAACAAATCTAAAAAAGAGTTTAAGGCCTTAAGGAGT
ATCTACAACGCCGCCGGTGAAGCCGCCGATAACCGCGTTAAGGAACTGGATTTACAGGCCTCAGAGCAGGCCACCACGCA
AACCCAAATTTCGGTCACCATAGCCACCTTAGTCGCGATAGTAGCTCTCGTGATCGCCTACTTTGGTCCCAAAATCATAG
TCAATGCGATCCGCGATATTACCGACAGGATCAACGATATTGTCGATGGCGACGGAAACTTAACCCAACGAATCCCCATC
ACCCGTCAAGATGAAATTGGCGAGCTAGCCAATGCCTTTAACTTGTTTGTGGCCCAATTGCAGCAAATGGTTATCGCGAT
TATCAGCCAAACCAAAGATGTCAGCCAAACCGTTGAAAATCTCGCGACAAAATCAACCACCACCATAGGCATCAGTTACG
AGCAGGAACAGTTTGTCGATACCATAGTCACGGCGGTGAATGAGATGAGCGCTGCGGTGCGAGAGGTGGCCAGCAACGCC
CTGCATACCGCCACCGAAATAACTAAAGTCAACGACCAAACCATTGAGGGTAAAAATATCCTTACCCAGTCGGTTAACCA
TATTCAGCAACTGTCTGAGTCGGTGAAACAAGCCGTGGCGGTTATCGAAAAACTCTCAGTGAATTCCGCCAATATCGCCT
CGGTATTGGATGTTATCCGCTCGATTGCAGAGCAAACTAACCTACTCGCCCTCAACGCCGCCATTGAGGCGGCCCGTGCG
GGTGAGCAAGGACGCGGCTTTGCGGTGGTTGCCGATGAGGTGCGGACACTGGCGAGCCGCACCGAAACCTCGACCCAAGA
TATTCAGCGTATGATTGAGGAGTTACAACGGGGTGTAAATGATGCAGTTAAGAGCATTGAATCGGGCGCCAGCCTCACGA
ACTCGACCGTGACCCTCGCCAGTCAGACACAGGATGCCTTAGATGAGATCCTGAACTCCACCTCTAAGGTCAGTGAGATG
TCGACCCAAACCGCCACGGCCACCGAAGAGCAAACCCATGTGACCGAAGAAATCAATCGCAACTTGACCGAGCTGTCTGA
CAAAACCCGCTACTGCAATACCGTTATCCAAGAGACTCAGCAAATCGTCGTCAACACCCAAACCATTTGCAGCAACTTAC
AAAAAGAAGTGTCACGCTTTAAAGTCGCTTAA

Upstream 100 bases:

>100_bases
CATCGCTTCTAATACAGACTTTTCGCAGGCTGCTGCAAACAACCAAATAGCGACTAAGCTATTTAATAAGTCGTTTTGTC
AGAGAGTTATGGAGAGTCCC

Downstream 100 bases:

>100_bases
CGAGAGTAACGCGCCCAGATGTCCCTGACTTCGCGTCGCTCAAAGACAGATAAAAAAGAGTGCCTAGGCACTCTTTTTTA
TGGATTAGAGGATACGCTGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQNRTTLKQMQEFSQRFNPAISAILNADRDLYQAQLSEEVLLRPELSSENRK
SEIDNWQENVDQARDRMGEFKNYLQDHLEVIKSTSGFEAQFSLWYQASSEVINAVKNNDFELARQLHENKSKKEFKALRS
IYNAAGEAADNRVKELDLQASEQATTQTQISVTIATLVAIVALVIAYFGPKIIVNAIRDITDRINDIVDGDGNLTQRIPI
TRQDEIGELANAFNLFVAQLQQMVIAIISQTKDVSQTVENLATKSTTTIGISYEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTIEGKNILTQSVNHIQQLSESVKQAVAVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTNSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNTVIQETQQIVVNTQTICSNLQKEVSRFKVA

Sequences:

>Translated_543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQNRTTLKQMQEFSQRFNPAISAILNADRDLYQAQLSEEVLLRPELSSENRK
SEIDNWQENVDQARDRMGEFKNYLQDHLEVIKSTSGFEAQFSLWYQASSEVINAVKNNDFELARQLHENKSKKEFKALRS
IYNAAGEAADNRVKELDLQASEQATTQTQISVTIATLVAIVALVIAYFGPKIIVNAIRDITDRINDIVDGDGNLTQRIPI
TRQDEIGELANAFNLFVAQLQQMVIAIISQTKDVSQTVENLATKSTTTIGISYEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTIEGKNILTQSVNHIQQLSESVKQAVAVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTNSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNTVIQETQQIVVNTQTICSNLQKEVSRFKVA
>Mature_543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQNRTTLKQMQEFSQRFNPAISAILNADRDLYQAQLSEEVLLRPELSSENRK
SEIDNWQENVDQARDRMGEFKNYLQDHLEVIKSTSGFEAQFSLWYQASSEVINAVKNNDFELARQLHENKSKKEFKALRS
IYNAAGEAADNRVKELDLQASEQATTQTQISVTIATLVAIVALVIAYFGPKIIVNAIRDITDRINDIVDGDGNLTQRIPI
TRQDEIGELANAFNLFVAQLQQMVIAIISQTKDVSQTVENLATKSTTTIGISYEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTIEGKNILTQSVNHIQQLSESVKQAVAVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTNSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNTVIQETQQIVVNTQTICSNLQKEVSRFKVA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=423, Percent_Identity=24.113475177305, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788195, Length=342, Percent_Identity=27.1929824561404, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787690, Length=526, Percent_Identity=24.3346007604563, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788194, Length=349, Percent_Identity=28.080229226361, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789453, Length=349, Percent_Identity=27.7936962750716, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60081; Mature: 60081

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSIRVKFSLMFAIMATALIVMAVTDAMQNRTTLKQMQEFSQRFNPAISAILNADRDLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QAQLSEEVLLRPELSSENRKSEIDNWQENVDQARDRMGEFKNYLQDHLEVIKSTSGFEAQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FSLWYQASSEVINAVKNNDFELARQLHENKSKKEFKALRSIYNAAGEAADNRVKELDLQA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SEQATTQTQISVTIATLVAIVALVIAYFGPKIIVNAIRDITDRINDIVDGDGNLTQRIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCC
TRQDEIGELANAFNLFVAQLQQMVIAIISQTKDVSQTVENLATKSTTTIGISYEQEQFVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHHHH
TIVTAVNEMSAAVREVASNALHTATEITKVNDQTIEGKNILTQSVNHIQQLSESVKQAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TETSTQDIQRMIEELQRGVNDAVKSIESGASLTNSTVTLASQTQDALDEILNSTSKVSEM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
STQTATATEEQTHVTEEINRNLTELSDKTRYCNTVIQETQQIVVNTQTICSNLQKEVSRF
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVA
CCC
>Mature Secondary Structure
MFNSIRVKFSLMFAIMATALIVMAVTDAMQNRTTLKQMQEFSQRFNPAISAILNADRDLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QAQLSEEVLLRPELSSENRKSEIDNWQENVDQARDRMGEFKNYLQDHLEVIKSTSGFEAQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FSLWYQASSEVINAVKNNDFELARQLHENKSKKEFKALRSIYNAAGEAADNRVKELDLQA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SEQATTQTQISVTIATLVAIVALVIAYFGPKIIVNAIRDITDRINDIVDGDGNLTQRIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCC
TRQDEIGELANAFNLFVAQLQQMVIAIISQTKDVSQTVENLATKSTTTIGISYEQEQFVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHHHH
TIVTAVNEMSAAVREVASNALHTATEITKVNDQTIEGKNILTQSVNHIQQLSESVKQAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TETSTQDIQRMIEELQRGVNDAVKSIESGASLTNSTVTLASQTQDALDEILNSTSKVSEM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
STQTATATEEQTHVTEEINRNLTELSDKTRYCNTVIQETQQIVVNTQTICSNLQKEVSRF
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]