Click here to switch to the map view.

The map label for this gene is yeaP [H]

Identifier: 117919285

GI number: 117919285

Start: 965846

End: 966814

Strand: Direct

Name: yeaP [H]

Synonym: Shewana3_0833

Alternate gene names: 117919285

Gene position: 965846-966814 (Clockwise)

Preceding gene: 117919284

Following gene: 117919287

Centisome position: 19.42

GC content: 48.5

Gene sequence:

>969_bases
ATGCAATTACCTCCAGTTCCTGAAAACGAGTTGCAGCGTTTAGCTACTCTAAGAGCGCTGAATGTACTCGATACCGATGC
CGAAGAAAGATTCGATAGGATCACTCGATTGACTCGGCGGATCTTTTCACTGCCCATTTGTTTAGTGACCCTAGTCGATG
CGAATCGCCAGTGGTTTAAATCTCGCCAAGGGATAGAAGTGGAGCAAACCCCTAGGGATATTTCCCTCTGCGCCCATGCG
ATTAATCATGATGGGATTTTCGTTGTGCATGATGCGCTAAAGGATCCACGCTTTTGTGATAATCCTTTAGTCACTGAGCC
GCCCCATATTCGTTTTTATGTGGGTTACCCTCTTACCATCCAAGGGGAATATCGGGTCGGTACTCTGTGCTTAATCGGTA
ATGAACCGCGCGATTTTACCGAAGAAGATGCCGAAACCTTAACGGATCTCGGGCAAATGGTGGAGGCTGAGCTCTTGTCC
ATCGCGCAAAATACCTTAGACCCACTGACCATGATCTCCAATCGCCGAGGGTTTGAGTTGCTCGCCTATCAATCGCTGGC
GAGTTGTCGTCGTACCGATGCTGAGGCTGCCTTAGTCTTTTTCGACCTCGACTTTTTTAAGGAGGTAAACGATAGCTTTG
GTCACCGTAAGGGCGACCAATTGCTCTATGATTTTGCCCATATTTTGATGGCGGCCTTTAGGGAGTCCGATGTGATTGCA
CGGCTAGGCGGCGATGAGTTTGTGGTGCTATTAAGTTTTATCGAGCGCGATACAGTGAACTTTGCGATTGAGCGCTTTAA
GCTGTTACTTGGCGAGTATAATCAACAACATTCAGAGCATCCCCTCGAAACCAGCATAGGCATAGCCCATTGGTCGCCAG
CATCGGATATGAATCTGGATGATCTACTCGACGCGGCCGATCGAGCCATGTATCGAGATAAAGCGGTGCATCACTTGGAT
AAGCCTTAG

Upstream 100 bases:

>100_bases
AAAGCTACGGAGGAATAGCAGGGCGGTTAACGCCATTCCTTGCTGTTCCACTCCTTGGGCTTAGACTAAGCTTGATTAAG
AGCCGTTAGCGGAGCGTACT

Downstream 100 bases:

>100_bases
TTAATCGGGTCGTAGACTCTGTGTTAATCAGATTTATAAGATAAACAGGTTTATAAGGTAAAAAGGGAGACTGTAGTCTC
CCTTTTCATGGGTGAAAATT

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQLPPVPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICLVTLVDANRQWFKSRQGIEVEQTPRDISLCAHA
INHDGIFVVHDALKDPRFCDNPLVTEPPHIRFYVGYPLTIQGEYRVGTLCLIGNEPRDFTEEDAETLTDLGQMVEAELLS
IAQNTLDPLTMISNRRGFELLAYQSLASCRRTDAEAALVFFDLDFFKEVNDSFGHRKGDQLLYDFAHILMAAFRESDVIA
RLGGDEFVVLLSFIERDTVNFAIERFKLLLGEYNQQHSEHPLETSIGIAHWSPASDMNLDDLLDAADRAMYRDKAVHHLD
KP

Sequences:

>Translated_322_residues
MQLPPVPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICLVTLVDANRQWFKSRQGIEVEQTPRDISLCAHA
INHDGIFVVHDALKDPRFCDNPLVTEPPHIRFYVGYPLTIQGEYRVGTLCLIGNEPRDFTEEDAETLTDLGQMVEAELLS
IAQNTLDPLTMISNRRGFELLAYQSLASCRRTDAEAALVFFDLDFFKEVNDSFGHRKGDQLLYDFAHILMAAFRESDVIA
RLGGDEFVVLLSFIERDTVNFAIERFKLLLGEYNQQHSEHPLETSIGIAHWSPASDMNLDDLLDAADRAMYRDKAVHHLD
KP
>Mature_322_residues
MQLPPVPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICLVTLVDANRQWFKSRQGIEVEQTPRDISLCAHA
INHDGIFVVHDALKDPRFCDNPLVTEPPHIRFYVGYPLTIQGEYRVGTLCLIGNEPRDFTEEDAETLTDLGQMVEAELLS
IAQNTLDPLTMISNRRGFELLAYQSLASCRRTDAEAALVFFDLDFFKEVNDSFGHRKGDQLLYDFAHILMAAFRESDVIA
RLGGDEFVVLLSFIERDTVNFAIERFKLLLGEYNQQHSEHPLETSIGIAHWSPASDMNLDDLLDAADRAMYRDKAVHHLD
KP

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=261, Percent_Identity=32.5670498084291, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786584, Length=152, Percent_Identity=32.8947368421053, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788381, Length=124, Percent_Identity=40.3225806451613, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=207, Percent_Identity=29.951690821256, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787262, Length=153, Percent_Identity=34.640522875817, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693134, Length=149, Percent_Identity=29.5302013422819, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082007, Length=151, Percent_Identity=29.8013245033113, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787802, Length=155, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36788; Mature: 36788

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPPVPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICLVTLVDANRQWFK
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SRQGIEVEQTPRDISLCAHAINHDGIFVVHDALKDPRFCDNPLVTEPPHIRFYVGYPLTI
HCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEE
QGEYRVGTLCLIGNEPRDFTEEDAETLTDLGQMVEAELLSIAQNTLDPLTMISNRRGFEL
ECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
LAYQSLASCRRTDAEAALVFFDLDFFKEVNDSFGHRKGDQLLYDFAHILMAAFRESDVIA
HHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHE
RLGGDEFVVLLSFIERDTVNFAIERFKLLLGEYNQQHSEHPLETSIGIAHWSPASDMNLD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCCCCCCCHH
DLLDAADRAMYRDKAVHHLDKP
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLPPVPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICLVTLVDANRQWFK
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SRQGIEVEQTPRDISLCAHAINHDGIFVVHDALKDPRFCDNPLVTEPPHIRFYVGYPLTI
HCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEE
QGEYRVGTLCLIGNEPRDFTEEDAETLTDLGQMVEAELLSIAQNTLDPLTMISNRRGFEL
ECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
LAYQSLASCRRTDAEAALVFFDLDFFKEVNDSFGHRKGDQLLYDFAHILMAAFRESDVIA
HHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHE
RLGGDEFVVLLSFIERDTVNFAIERFKLLLGEYNQQHSEHPLETSIGIAHWSPASDMNLD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCCCCCCCHH
DLLDAADRAMYRDKAVHHLDKP
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]