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The map label for this gene is hlyB [H]

Identifier: 117919261

GI number: 117919261

Start: 933343

End: 935043

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_0809

Alternate gene names: 117919261

Gene position: 933343-935043 (Clockwise)

Preceding gene: 117919256

Following gene: 117919263

Centisome position: 18.77

GC content: 48.21

Gene sequence:

>1701_bases
ATGGGCCGTTTTTTAAAAGATCTCAGCATCAAGCATAAGATGTTTGCCCTCGTTGGGATGATGCTAGTGTTGATGTTGCT
GTTATCAGGCTTTAGTTTGCTGAAAATGAAGCGAGTGTCGGACGAAGTCCATGGTATTGCGACCGAGAATATTCCACTCG
TTAGGCTGTCTACCGATGTGACGATTCAACAGCTTGAAAGCTCGATTATCCTCGAAAAGGCTTTTCGTGCCTCGGACATT
AAAGTCTCTCCCGAACAAAGGTTGATAGATGGTTTTATTGCCGACGTGATAAAGCATAAAGAGTTGATAAATCATGAATT
ACAATCGACTCAAACCATGCTCAATGATGCGCTGAAATTATCTCAACCCGCTGAGCTGCGCGACAAAACCCTACAATTGA
GTCAAGAGATTGCCAACATCATCCAAGGCTTTCGTCACTACGACGCCCAATTAGTGGCTGTGATAGCGGGAATTGAGCAA
AAACAGGAGTCTGCCCTGTTAGCGCAGCGAGTTGATGCGCTAGAGAAAACGCAAAAAGAGTTCAATACCGAGTTAAGCCA
ATTTGCGCTGCAATTGGAGCAAATGACGAAGACAGCGGTATCTGTGACCGAAGAGGAAGAGATTAAGGCCGCCTACGGTA
TGATGATTATCTCCTCAATTGCGGTCGTTATCGGTTTATTTGTCGGACTGCTTTCTAGTCGTTACATAGTGCAATCCATC
ACCCAGCTGCGTAATGCGGCCTCCTTAATGCAATCGGGAAATTTTAGCCACGAACTTGCCGTCACCTCAAAGGACGAATT
AGGTGAGTTGACCATAAGCATGAATCAAATGGCATTAACCTTAAGCAAAACCGTGGGGCAAGTGGTTGATCGTAGCGAAG
AAATCGCTTCGATGGTCACAGAGCTTAATGCGGTGGCCGAAAACAATCGCGAGGCGATACTGAAACAGCAGGACAATACG
GATCAGGTCGCCGCCTCTATGACACAAATGGCCGCGACGATTACCGAGGTGGCCTGCAGCGCCGAGACGGCATCCTTTTC
GGCGGGACAGGCGGAAAACAGAGCGAAGGAGAGCTGTGGCGTTGTTGAGGCTAGCGAGAAAATCACTCAACAATTGGTCG
TTAGCGCTCAACATTCGAGTCAACTTATTCAGCAATTACAGGCCAGTACGGGCAAGATCTTAAACTTTGTGTCGGTAGTG
GATGCGATTGCCGGGCAAACGAATCTGTTGGCGTTAAATGCCTCGATTGAGGCGGCGCGGGCGGGCGATCAAGGCCGAGG
ATTTGCCGTGGTGGCCGATGAGGTGCGAGCATTAGCGACTCGTAGCCAAACGGCAACACAGGAAATCAGTGAGCTTATCC
AAACCTTAGTGGTCGATGCTAAATCGGCTGTGAGTTCCTTTGAGGAAAATGAACGTCAAATCAGTGAGTCATCCGTACTG
GTTAATCAAATTAAACAGAACTTATTTGAGATATTAGATGCATTGACGCAACTTTCGCAGGCGAACTCGCAGGTAGCGAC
CGCGAGTGAGGAGCAGGCGGTCACGGCGGAAGATATTAGCGAGCGCATTAATGCGATACGTGATTCGGGGGAGCTCGTTT
TAAATAGTGCTTTCGAAACGGCTAAAGCCAGTGAGTCATTATCGCAACAGGCAAATTCGTTGCGGGAGGGGATGCAGCAG
TTTAAGGTTCGAATCGTCTAG

Upstream 100 bases:

>100_bases
TAGTTTTTTCTTGAGTTTAGCTTCAATTCTTCCGCTCTTGTTGAAAACTGCGACTATCCTAAATAAAGGATGAGCAGCGC
TATTCATGGAGAGAGGTTTT

Downstream 100 bases:

>100_bases
ATTTAAGCGTGTGTGACATCCATAAAAAATGCCCAGCTTATAAAGTTGGGCATTTTTATGGAGCTTAACTCAAGGTATCA
CATTGCTTAAAACCACGGTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MGRFLKDLSIKHKMFALVGMMLVLMLLLSGFSLLKMKRVSDEVHGIATENIPLVRLSTDVTIQQLESSIILEKAFRASDI
KVSPEQRLIDGFIADVIKHKELINHELQSTQTMLNDALKLSQPAELRDKTLQLSQEIANIIQGFRHYDAQLVAVIAGIEQ
KQESALLAQRVDALEKTQKEFNTELSQFALQLEQMTKTAVSVTEEEEIKAAYGMMIISSIAVVIGLFVGLLSSRYIVQSI
TQLRNAASLMQSGNFSHELAVTSKDELGELTISMNQMALTLSKTVGQVVDRSEEIASMVTELNAVAENNREAILKQQDNT
DQVAASMTQMAATITEVACSAETASFSAGQAENRAKESCGVVEASEKITQQLVVSAQHSSQLIQQLQASTGKILNFVSVV
DAIAGQTNLLALNASIEAARAGDQGRGFAVVADEVRALATRSQTATQEISELIQTLVVDAKSAVSSFEENERQISESSVL
VNQIKQNLFEILDALTQLSQANSQVATASEEQAVTAEDISERINAIRDSGELVLNSAFETAKASESLSQQANSLREGMQQ
FKVRIV

Sequences:

>Translated_566_residues
MGRFLKDLSIKHKMFALVGMMLVLMLLLSGFSLLKMKRVSDEVHGIATENIPLVRLSTDVTIQQLESSIILEKAFRASDI
KVSPEQRLIDGFIADVIKHKELINHELQSTQTMLNDALKLSQPAELRDKTLQLSQEIANIIQGFRHYDAQLVAVIAGIEQ
KQESALLAQRVDALEKTQKEFNTELSQFALQLEQMTKTAVSVTEEEEIKAAYGMMIISSIAVVIGLFVGLLSSRYIVQSI
TQLRNAASLMQSGNFSHELAVTSKDELGELTISMNQMALTLSKTVGQVVDRSEEIASMVTELNAVAENNREAILKQQDNT
DQVAASMTQMAATITEVACSAETASFSAGQAENRAKESCGVVEASEKITQQLVVSAQHSSQLIQQLQASTGKILNFVSVV
DAIAGQTNLLALNASIEAARAGDQGRGFAVVADEVRALATRSQTATQEISELIQTLVVDAKSAVSSFEENERQISESSVL
VNQIKQNLFEILDALTQLSQANSQVATASEEQAVTAEDISERINAIRDSGELVLNSAFETAKASESLSQQANSLREGMQQ
FKVRIV
>Mature_565_residues
GRFLKDLSIKHKMFALVGMMLVLMLLLSGFSLLKMKRVSDEVHGIATENIPLVRLSTDVTIQQLESSIILEKAFRASDIK
VSPEQRLIDGFIADVIKHKELINHELQSTQTMLNDALKLSQPAELRDKTLQLSQEIANIIQGFRHYDAQLVAVIAGIEQK
QESALLAQRVDALEKTQKEFNTELSQFALQLEQMTKTAVSVTEEEEIKAAYGMMIISSIAVVIGLFVGLLSSRYIVQSIT
QLRNAASLMQSGNFSHELAVTSKDELGELTISMNQMALTLSKTVGQVVDRSEEIASMVTELNAVAENNREAILKQQDNTD
QVAASMTQMAATITEVACSAETASFSAGQAENRAKESCGVVEASEKITQQLVVSAQHSSQLIQQLQASTGKILNFVSVVD
AIAGQTNLLALNASIEAARAGDQGRGFAVVADEVRALATRSQTATQEISELIQTLVVDAKSAVSSFEENERQISESSVLV
NQIKQNLFEILDALTQLSQANSQVATASEEQAVTAEDISERINAIRDSGELVLNSAFETAKASESLSQQANSLREGMQQF
KVRIV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=388, Percent_Identity=29.8969072164948, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI2367378, Length=340, Percent_Identity=31.7647058823529, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1788194, Length=341, Percent_Identity=30.791788856305, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=30.3116147308782, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789453, Length=255, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61636; Mature: 61505

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRFLKDLSIKHKMFALVGMMLVLMLLLSGFSLLKMKRVSDEVHGIATENIPLVRLSTDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
TIQQLESSIILEKAFRASDIKVSPEQRLIDGFIADVIKHKELINHELQSTQTMLNDALKL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SQPAELRDKTLQLSQEIANIIQGFRHYDAQLVAVIAGIEQKQESALLAQRVDALEKTQKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTELSQFALQLEQMTKTAVSVTEEEEIKAAYGMMIISSIAVVIGLFVGLLSSRYIVQSI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLRNAASLMQSGNFSHELAVTSKDELGELTISMNQMALTLSKTVGQVVDRSEEIASMVT
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHH
ELNAVAENNREAILKQQDNTDQVAASMTQMAATITEVACSAETASFSAGQAENRAKESCG
HHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
VVEASEKITQQLVVSAQHSSQLIQQLQASTGKILNFVSVVDAIAGQTNLLALNASIEAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHH
AGDQGRGFAVVADEVRALATRSQTATQEISELIQTLVVDAKSAVSSFEENERQISESSVL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQIKQNLFEILDALTQLSQANSQVATASEEQAVTAEDISERINAIRDSGELVLNSAFET
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
AKASESLSQQANSLREGMQQFKVRIV
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRFLKDLSIKHKMFALVGMMLVLMLLLSGFSLLKMKRVSDEVHGIATENIPLVRLSTDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
TIQQLESSIILEKAFRASDIKVSPEQRLIDGFIADVIKHKELINHELQSTQTMLNDALKL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SQPAELRDKTLQLSQEIANIIQGFRHYDAQLVAVIAGIEQKQESALLAQRVDALEKTQKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTELSQFALQLEQMTKTAVSVTEEEEIKAAYGMMIISSIAVVIGLFVGLLSSRYIVQSI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLRNAASLMQSGNFSHELAVTSKDELGELTISMNQMALTLSKTVGQVVDRSEEIASMVT
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHH
ELNAVAENNREAILKQQDNTDQVAASMTQMAATITEVACSAETASFSAGQAENRAKESCG
HHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
VVEASEKITQQLVVSAQHSSQLIQQLQASTGKILNFVSVVDAIAGQTNLLALNASIEAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHH
AGDQGRGFAVVADEVRALATRSQTATQEISELIQTLVVDAKSAVSSFEENERQISESSVL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQIKQNLFEILDALTQLSQANSQVATASEEQAVTAEDISERINAIRDSGELVLNSAFET
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
AKASESLSQQANSLREGMQQFKVRIV
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]