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The map label for this gene is alr [H]

Identifier: 117919166

GI number: 117919166

Start: 831036

End: 832112

Strand: Direct

Name: alr [H]

Synonym: Shewana3_0714

Alternate gene names: 117919166

Gene position: 831036-832112 (Clockwise)

Preceding gene: 117919165

Following gene: 117919168

Centisome position: 16.71

GC content: 51.81

Gene sequence:

>1077_bases
TTGAAACCTTTTCCCCGAGCAGAAATTAGCAGTAGTGCACTGCAGAACAATCTCGCCGTCTTGCGTCAACAGGCGAGTCG
CAGCCAAGTAATGGCGGTGGTGAAAGCCAATGGTTATGGTCATGGATTATTAAATGTCGCCAATTGTTTACATACGGCTG
ATGGCTTTGGTTTAGCCCGTTTAGAAGAGGCCTTAGAGCTGCGCGCTGGTGGCGTGAAGGCGCGCTTGTTATTGCTTGAA
GGCTTCTTTCGCAGCACTGATTTACCTTTGTTGGTGGCCCACGATATCGATACTGTGGTGCACCACGAGTCGCAAATCGA
AATGTTAGAGCAGGCGACGCTATCAAAACCTGTCACTGTATGGTTGAAAGTGGATTCCGGCATGCATCGTTTAGGCGTAA
CCCCTGAGCAATTTACGCAGGTGTATGCGCGCTTGATGGCCTGTGACAATGTCGCCAAGCCCATCCATTTGATGACTCAC
TTTGCCTGTGCCGATGAGCCTGAAAATCATTACACCCAAGTGCAAATGCAAACCTTTAATCAGTTAACCGCGGATTTACC
TGGGTTTAGAACCTTAGCCAATTCTGCGGGCGCCCTCTATTGGCCCAAGAGCCAAGGGGACTGGATCCGCCCTGGGATCG
CGCTCTATGGCGTGTCGCCGGTGACAGGGGATTGCGGCGCCAACCATGGTCTGATCCCGGCGATGAATTTAGTCTCGCGT
TTAATTGCGGTGCGTGACCACAAGGCAGGACAACCCGTTGGCTATGGTTGTTATTGGACGGCGAAACAAGATACTCGCCT
TGGCGTTGTCGCGATTGGTTATGGCGACGGTTATCCGCGTAATGCGCCAGAAGGCACGCCCGTGTGGGTTAATGGTCGCC
GAGTACCGATCGTTGGTCGTGTATCTATGGATATGTTAACTGTTGATTTAGGTGCTGATGCGACAGACCTTGTGGGCGAT
GAAGCATTGCTCTGGGGCGCCGCTTTACCCGTTGAGGAAGTGGCTGAACATATTGGCACCATCGCCTATGAGTTAGTGAC
TAAACTCACTCCAAGGGTTGCGGTGTGTCTTGCATAA

Upstream 100 bases:

>100_bases
TGGCCCGCAGTTTGAAGAAGATTAATTTCTGGTGTTAGAAGCTAAGCACTGTTTACGTATTCTTTTTATTTCCTGACTTT
TCAAATAGACAAGGCAAATT

Downstream 100 bases:

>100_bases
GCCATTGGAGTGAATACCAAAACGGCGCATTTGCGCCGTTTTTTTTGCCCTGAAAGCGGATGATTGAGAGAACTGTCAGC
CGTTCTGCACTTGGTTATTG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLARLEEALELRAGGVKARLLLLE
GFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTVWLKVDSGMHRLGVTPEQFTQVYARLMACDNVAKPIHLMTH
FACADEPENHYTQVQMQTFNQLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGADATDLVGD
EALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA

Sequences:

>Translated_358_residues
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLARLEEALELRAGGVKARLLLLE
GFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTVWLKVDSGMHRLGVTPEQFTQVYARLMACDNVAKPIHLMTH
FACADEPENHYTQVQMQTFNQLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGADATDLVGD
EALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
>Mature_358_residues
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLARLEEALELRAGGVKARLLLLE
GFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTVWLKVDSGMHRLGVTPEQFTQVYARLMACDNVAKPIHLMTH
FACADEPENHYTQVQMQTFNQLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGADATDLVGD
EALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=348, Percent_Identity=57.7586206896552, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=44.3181818181818, Blast_Score=281, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38766; Mature: 38766

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
LEEALELRAGGVKARLLLLEGFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTV
HHHHHHHHCCCHHEEHEEHHHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHCCCCEEE
WLKVDSGMHRLGVTPEQFTQVYARLMACDNVAKPIHLMTHFACADEPENHYTQVQMQTFN
EEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHEEEHHHHHH
QLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
HHHHCCCCHHHHHCCCCEEEECCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGR
HHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEEEE
VSMDMLTVDLGADATDLVGDEALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
CEEEEEEEECCCCHHHHCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
LEEALELRAGGVKARLLLLEGFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTV
HHHHHHHHCCCHHEEHEEHHHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHCCCCEEE
WLKVDSGMHRLGVTPEQFTQVYARLMACDNVAKPIHLMTHFACADEPENHYTQVQMQTFN
EEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHEEEHHHHHH
QLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
HHHHCCCCHHHHHCCCCEEEECCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGR
HHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEEEE
VSMDMLTVDLGADATDLVGDEALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
CEEEEEEEECCCCHHHHCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]