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The map label for this gene is zraR [H]

Identifier: 117918980

GI number: 117918980

Start: 616916

End: 618280

Strand: Direct

Name: zraR [H]

Synonym: Shewana3_0526

Alternate gene names: 117918980

Gene position: 616916-618280 (Clockwise)

Preceding gene: 117918979

Following gene: 117918981

Centisome position: 12.41

GC content: 49.52

Gene sequence:

>1365_bases
ATGGATGAAATCGGTAAGCCTGCTCCCGCAGAAACACGTTGGAAACGGTGGTTGTTAGTACTCGACCCCGAGCAATGTCT
GCCGGAGTGTAGTGAAGAACTGAAACAAGCGGCTTGGAACTGTGTAAAAGCAGTGTCGGCGGCCGAAGCCTTAGTATTGC
TGCAAAAATATGAGTTGCGCGTCGCCATTGCCTTTATCAGCGACACTAACCAAACTGCGCTGGCGAAAGAAATTGCCATT
ATTCAAGCCGAATATCCCTCCTTGCATTGGATTGCCGTTACCGATAGCGCCTTGGAGCAGCATTGCAGCTGGCTCAGCGC
CGCTAATTTTGTTGATTATTACCATCGCCCATTTGATTGGAATCGCTTTGCCGATACCCTTGGACACGCTTGGGGCATGG
CGCAGTTGACGCCATCGAAAGGAGGGAAGGGACCTGCAAAGGTTTTAACGACCATTAAGGGGGAGCATCCCTTATTGCAA
CAGCTGCGTCAGCGGCTGCATAAATTTAGTCAGTCGGATGAAACCGTATTACTGAGCGGTGAAACGGGCTCTGGCAAAGG
ACTATGTGCTAAAACCTTACATAGTTTATCTAAAAGGCACGAAGGGCCATTTATCACAGTCAATTGTGGCGCGCTGCCTA
CAGGGCTTATCCATTCCACCCTCTTTGGCCATGAGAAAGGCGCCTTTACCGACGCCGATAAACGGTATATCGGTCATTTA
GAGCAGGCCCATGGTGGGACACTGTTTTTAGATGAAATTGCCGATCTCCCCTTAGACTTACAGGTCAACTTACTGCACTT
TTTGGATGATAAACACATTATGCGAATTGGCGGCAATGCGCCCATAAAAGTGGATTGCCGTTTGTTATTTGCCTCCCACC
AGGATTTAGAGGCCGCGATTGACGAAGGCCGCTTTCGTGAAGATTTATATCACCGTATCAATGTGTTACGCCTGCATGTG
CCAAGTTTGAGACAGTATAGCGACGAGGTCATGCTGCTCGCCGAACAATTCTTGTTAGAACATTCGGACAACTGTACTCA
GTTTCATTTTAGTGACGAGGCCCGCTGTGCGATGAAACACTACAATTGGCCGGGCAATGTGCGGGAGCTGCGTAACCGGA
TCCGCCGGGCTATGGTCTTAACCGATGACTGCATTATTACTGCGCAGTTGTTAGGGCTAGATTCACTCACGGCAAACCGT
ACCAGCCAAGATCTCGCGCGCTGCCGCGCAGAGCATGAGGCAGAAGTATTACTGAAAGCCATTAGCGACCATAAACATAA
TATTTCCGCCGCCGCCCGCTCATTAAATATCTCCAGAGCGACCTTCTATCGACTCCTGAAAAAGTGTCAGATCAAGGTGC
CTTAG

Upstream 100 bases:

>100_bases
TACTGCGTTTAGGCCGGTTAACTCATGCTGGTCAGGTTTGTCGGGAGGCCATTGTCCTTCTAAACTTGATTAGTAATAGG
TTCATCTCCCACCCCTTCCT

Downstream 100 bases:

>100_bases
TCCGTCTATTTATCCTGCGACAGTCTGCTTCACCGCTGTGACACATCTTATCCAGTCATCTCTTTTAATTTCTTATATAT
CAATGCATTAAATTTTGGCT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MDEIGKPAPAETRWKRWLLVLDPEQCLPECSEELKQAAWNCVKAVSAAEALVLLQKYELRVAIAFISDTNQTALAKEIAI
IQAEYPSLHWIAVTDSALEQHCSWLSAANFVDYYHRPFDWNRFADTLGHAWGMAQLTPSKGGKGPAKVLTTIKGEHPLLQ
QLRQRLHKFSQSDETVLLSGETGSGKGLCAKTLHSLSKRHEGPFITVNCGALPTGLIHSTLFGHEKGAFTDADKRYIGHL
EQAHGGTLFLDEIADLPLDLQVNLLHFLDDKHIMRIGGNAPIKVDCRLLFASHQDLEAAIDEGRFREDLYHRINVLRLHV
PSLRQYSDEVMLLAEQFLLEHSDNCTQFHFSDEARCAMKHYNWPGNVRELRNRIRRAMVLTDDCIITAQLLGLDSLTANR
TSQDLARCRAEHEAEVLLKAISDHKHNISAAARSLNISRATFYRLLKKCQIKVP

Sequences:

>Translated_454_residues
MDEIGKPAPAETRWKRWLLVLDPEQCLPECSEELKQAAWNCVKAVSAAEALVLLQKYELRVAIAFISDTNQTALAKEIAI
IQAEYPSLHWIAVTDSALEQHCSWLSAANFVDYYHRPFDWNRFADTLGHAWGMAQLTPSKGGKGPAKVLTTIKGEHPLLQ
QLRQRLHKFSQSDETVLLSGETGSGKGLCAKTLHSLSKRHEGPFITVNCGALPTGLIHSTLFGHEKGAFTDADKRYIGHL
EQAHGGTLFLDEIADLPLDLQVNLLHFLDDKHIMRIGGNAPIKVDCRLLFASHQDLEAAIDEGRFREDLYHRINVLRLHV
PSLRQYSDEVMLLAEQFLLEHSDNCTQFHFSDEARCAMKHYNWPGNVRELRNRIRRAMVLTDDCIITAQLLGLDSLTANR
TSQDLARCRAEHEAEVLLKAISDHKHNISAAARSLNISRATFYRLLKKCQIKVP
>Mature_454_residues
MDEIGKPAPAETRWKRWLLVLDPEQCLPECSEELKQAAWNCVKAVSAAEALVLLQKYELRVAIAFISDTNQTALAKEIAI
IQAEYPSLHWIAVTDSALEQHCSWLSAANFVDYYHRPFDWNRFADTLGHAWGMAQLTPSKGGKGPAKVLTTIKGEHPLLQ
QLRQRLHKFSQSDETVLLSGETGSGKGLCAKTLHSLSKRHEGPFITVNCGALPTGLIHSTLFGHEKGAFTDADKRYIGHL
EQAHGGTLFLDEIADLPLDLQVNLLHFLDDKHIMRIGGNAPIKVDCRLLFASHQDLEAAIDEGRFREDLYHRINVLRLHV
PSLRQYSDEVMLLAEQFLLEHSDNCTQFHFSDEARCAMKHYNWPGNVRELRNRIRRAMVLTDDCIITAQLLGLDSLTANR
TSQDLARCRAEHEAEVLLKAISDHKHNISAAARSLNISRATFYRLLKKCQIKVP

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=420, Percent_Identity=37.1428571428571, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1790299, Length=454, Percent_Identity=35.6828193832599, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1788905, Length=418, Percent_Identity=32.2966507177034, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=39.7515527950311, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788550, Length=353, Percent_Identity=36.2606232294618, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082152, Length=319, Percent_Identity=38.871473354232, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI87081872, Length=300, Percent_Identity=38.6666666666667, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87082117, Length=226, Percent_Identity=43.3628318584071, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789087, Length=307, Percent_Identity=35.1791530944625, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=35.0157728706625, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787583, Length=236, Percent_Identity=33.8983050847458, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1789828, Length=249, Percent_Identity=34.136546184739, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081858, Length=325, Percent_Identity=28, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51156; Mature: 51156

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIGKPAPAETRWKRWLLVLDPEQCLPECSEELKQAAWNCVKAVSAAEALVLLQKYELR
CCCCCCCCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
VAIAFISDTNQTALAKEIAIIQAEYPSLHWIAVTDSALEQHCSWLSAANFVDYYHRPFDW
EEEEEEECCCCHHHHHHHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCH
NRFADTLGHAWGMAQLTPSKGGKGPAKVLTTIKGEHPLLQQLRQRLHKFSQSDETVLLSG
HHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
ETGSGKGLCAKTLHSLSKRHEGPFITVNCGALPTGLIHSTLFGHEKGAFTDADKRYIGHL
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
EQAHGGTLFLDEIADLPLDLQVNLLHFLDDKHIMRIGGNAPIKVDCRLLFASHQDLEAAI
HHCCCCEEEEHHHHCCCCCCEEHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCHHHHHH
DEGRFREDLYHRINVLRLHVPSLRQYSDEVMLLAEQFLLEHSDNCTQFHFSDEARCAMKH
HCCHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
YNWPGNVRELRNRIRRAMVLTDDCIITAQLLGLDSLTANRTSQDLARCRAEHEAEVLLKA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHH
ISDHKHNISAAARSLNISRATFYRLLKKCQIKVP
HHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDEIGKPAPAETRWKRWLLVLDPEQCLPECSEELKQAAWNCVKAVSAAEALVLLQKYELR
CCCCCCCCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
VAIAFISDTNQTALAKEIAIIQAEYPSLHWIAVTDSALEQHCSWLSAANFVDYYHRPFDW
EEEEEEECCCCHHHHHHHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCH
NRFADTLGHAWGMAQLTPSKGGKGPAKVLTTIKGEHPLLQQLRQRLHKFSQSDETVLLSG
HHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
ETGSGKGLCAKTLHSLSKRHEGPFITVNCGALPTGLIHSTLFGHEKGAFTDADKRYIGHL
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
EQAHGGTLFLDEIADLPLDLQVNLLHFLDDKHIMRIGGNAPIKVDCRLLFASHQDLEAAI
HHCCCCEEEEHHHHCCCCCCEEHHHHHHCCCEEEEECCCCCEEEEEEEEEECCCHHHHHH
DEGRFREDLYHRINVLRLHVPSLRQYSDEVMLLAEQFLLEHSDNCTQFHFSDEARCAMKH
HCCHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
YNWPGNVRELRNRIRRAMVLTDDCIITAQLLGLDSLTANRTSQDLARCRAEHEAEVLLKA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHH
ISDHKHNISAAARSLNISRATFYRLLKKCQIKVP
HHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]