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The map label for this gene is xerC [H]

Identifier: 117918850

GI number: 117918850

Start: 453548

End: 454447

Strand: Direct

Name: xerC [H]

Synonym: Shewana3_0393

Alternate gene names: 117918850

Gene position: 453548-454447 (Clockwise)

Preceding gene: 117918849

Following gene: 117918851

Centisome position: 9.12

GC content: 50.78

Gene sequence:

>900_bases
ATGACCCCGCAGTGTCAGTCCTATTTGCAGCAGTTTGAAACCTATATGCAGTCAGAGCGCCAGTTATCGGCGCATACGGT
TCGCAATTATATGTACGAGTTGCAGCGGGGAAGCGAGTTATTGCCCGAGGGTGTTGATTTGCTCAATGTGGGCCGTGAGC
ATTGGCAACAAGTGCTTGCTAAGCTGCATCGCAAGGGCTTGAGCCCACGCTCGCTATCATTGTGGTTGTCGGCCATCAAA
CAGTGGGGAGAGTTTTTATTGCGCTCAGGCGTGATTGAACTTAATCCTGCCAAGGGGCTGAGCGCGCCCAAACAAGCCAA
ACCGTTACCTAAGAATATCGACGTCGATTCTATCTCGCATCTGCTCGCGATTGAGGGTAATGATCCGCTGACCCTGCGTG
ATAAAGCCATTATGGAGCTGTTCTACTCCAGCGGATTGCGCTTGGCTGAACTGGCGGCGCTGGACTTATCCAGTGTGCAA
TACGATCAGCATGAAGTGCGCGTTTTGGGCAAAGGCAACAAAGAGCGCATAGTCCCCGTTGGGCGTTACGCCATAGAGGC
CATCAGTGCTTGGCTTAAGTGCCGCAAACAAATTTCCTGTGAAGATAATGCATTGTTTGTCACGGAGAAGGGCAAGCGTT
TGTCCCATCGCAGTATTCAGGCGCGCATGAGCAAATGGGGTCAGGAGCAGGCGCTTTCTATGCGGGTGCATCCCCATAAG
TTACGCCATTCCTTTGCGACGCACATGCTGGAATCCAGTGCCGATTTGCGGGCGGTGCAGGAATTATTAGGTCACGAAAA
CCTGTCGACCACGCAAATTTATACCAGTTTAGATTTCCAACACTTAGCTAAGGTGTATGATAACGCCCATCCTAGAGCGA
AAAAACAACAGGATAAATAA

Upstream 100 bases:

>100_bases
GTTGCTCGAACAATTACGCCGATTACTCGCACATATGCTGGCCAAGCTTTAAGGTAGATGGTTCGCCTTGCCTCAATTGC
CTAATGATGAGGAGCTGGAG

Downstream 100 bases:

>100_bases
TGCGTTGTTATCTTAGACCCCAGAATATTCGTGCGATCAGCTTCGATCTTGACGATACCTTATACGATAACGAGCCTCAT
ATTCTGAATGCCGAAGCCGA

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTPQCQSYLQQFETYMQSERQLSAHTVRNYMYELQRGSELLPEGVDLLNVGREHWQQVLAKLHRKGLSPRSLSLWLSAIK
QWGEFLLRSGVIELNPAKGLSAPKQAKPLPKNIDVDSISHLLAIEGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQ
YDQHEVRVLGKGNKERIVPVGRYAIEAISAWLKCRKQISCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHK
LRHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK

Sequences:

>Translated_299_residues
MTPQCQSYLQQFETYMQSERQLSAHTVRNYMYELQRGSELLPEGVDLLNVGREHWQQVLAKLHRKGLSPRSLSLWLSAIK
QWGEFLLRSGVIELNPAKGLSAPKQAKPLPKNIDVDSISHLLAIEGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQ
YDQHEVRVLGKGNKERIVPVGRYAIEAISAWLKCRKQISCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHK
LRHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK
>Mature_298_residues
TPQCQSYLQQFETYMQSERQLSAHTVRNYMYELQRGSELLPEGVDLLNVGREHWQQVLAKLHRKGLSPRSLSLWLSAIKQ
WGEFLLRSGVIELNPAKGLSAPKQAKPLPKNIDVDSISHLLAIEGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQY
DQHEVRVLGKGNKERIVPVGRYAIEAISAWLKCRKQISCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHKL
RHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=50.5084745762712, Blast_Score=290, Evalue=7e-80,
Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=34.7079037800687, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=27.2222222222222, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790768, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34113; Mature: 33981

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQCQSYLQQFETYMQSERQLSAHTVRNYMYELQRGSELLPEGVDLLNVGREHWQQVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KLHRKGLSPRSLSLWLSAIKQWGEFLLRSGVIELNPAKGLSAPKQAKPLPKNIDVDSISH
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHCCCCCCCCCHHHHHH
LLAIEGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQYDQHEVRVLGKGNKERIVPV
EEEECCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEEECCCCCCCEEEH
GRYAIEAISAWLKCRKQISCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHK
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHCCCHHH
LRHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TPQCQSYLQQFETYMQSERQLSAHTVRNYMYELQRGSELLPEGVDLLNVGREHWQQVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KLHRKGLSPRSLSLWLSAIKQWGEFLLRSGVIELNPAKGLSAPKQAKPLPKNIDVDSISH
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHCCCCCCCCCHHHHHH
LLAIEGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQYDQHEVRVLGKGNKERIVPV
EEEECCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEEECCCCCCCEEEH
GRYAIEAISAWLKCRKQISCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHK
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHCCCHHH
LRHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]