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The map label for this gene is fieF [H]

Identifier: 117918712

GI number: 117918712

Start: 286869

End: 287768

Strand: Direct

Name: fieF [H]

Synonym: Shewana3_0255

Alternate gene names: 117918712

Gene position: 286869-287768 (Clockwise)

Preceding gene: 117918711

Following gene: 117918713

Centisome position: 5.77

GC content: 52.0

Gene sequence:

>900_bases
ATGACTCAGACTTCCCAATACGATTTTTGGGTCAAACTGGCTAGTCGCGCTTCCGTGGCTACCGCTTTGACCCTTATTCT
TATCAAGCTGTTAGCTTGGTTATATTCTGGCTCGGCCAGTATGCTGGCGTCCTTAACGGATTCCTTCGCCGACGCACTCG
CCTCAATCATCAACTTTATCGCCATTCGTTATGCCATAGTCCCCGCCGACCATGACCACAGATACGGCCACGGTAAAGCG
GAGCCGTTAGCGTCGCTGGCGCAATCGGCCTTTATTATGGGCTCGGCATTCCTGCTGCTGTTTTATGGGGGAGAGCGGTT
ACTCAATCCCGCCCCGGTTGAGCACGCAACTTTAGGTGTGGTGGTCTCAGTCGTCGCGATTGTGTTGACATTAGCATTAG
TGATGTTGCAAAAGCGGGCGCTGGCGGCAACCAATAGCACGGTAGTTGAAGCCGATTCGTTGCACTATAAGTCGGATTTA
TTCCTCAATGGCGCCGTGTTGCTCGCACTCGTCTTGTCCCAATATGGCTGGTGGTGGGCCGATGGGCTCTTTGCTGTGCT
TATCGCTTGCTATATCGGCCAACAGGCATTTGACCTAGGTTACCGCTCTATTCAAGCGCTGCTCGACCGTGAGCTGGATG
AGGACACTCGTCAACGGATTAAACAAATCGCTAAGGAAGACTCCCGAGTCCAAGGGCTGCATGATTTGCGCACACGCCAA
GCGGGTAAGACTATCTTTATTCAATTCCATTTAGAGTTGGATGGCAATTTGAGTCTGAACGAAGCCCACAGTATTGCCGA
TACCACGGGACTGAGGGTGAAAGCCGCCTTTGAAGATGCCGAGGTGATTATTCACCAAGATCCTGTGCAGGTGGAACCTA
GTGCTGCGGCCTCATCATAA

Upstream 100 bases:

>100_bases
AGTTTAAAGCGCGATTTGAAGCACAAGCTGGTAAAGAACCTCGCGGTTAAGCTTGTAAGCTGATATACAATAGGGTCATA
GCTTCCCGATATAGACCCCT

Downstream 100 bases:

>100_bases
TAAGTTTGAATCGTTATTAAACAGCCAAAGGAATGGTTATGTCATGGACGCAGCAACAGGTTCACCCCTTAGCCGAACAG
ACTCGGCTCATCTGCCGTTA

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTQTSQYDFWVKLASRASVATALTLILIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEHATLGVVVSVVAIVLTLALVMLQKRALAATNSTVVEADSLHYKSDL
FLNGAVLLALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQ
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSAAASS

Sequences:

>Translated_299_residues
MTQTSQYDFWVKLASRASVATALTLILIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEHATLGVVVSVVAIVLTLALVMLQKRALAATNSTVVEADSLHYKSDL
FLNGAVLLALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQ
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSAAASS
>Mature_298_residues
TQTSQYDFWVKLASRASVATALTLILIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKAE
PLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEHATLGVVVSVVAIVLTLALVMLQKRALAATNSTVVEADSLHYKSDLF
LNGAVLLALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQA
GKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSAAASS

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=248, Percent_Identity=27.0161290322581, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790349, Length=275, Percent_Identity=48.3636363636364, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI115533508, Length=271, Percent_Identity=23.9852398523985, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533506, Length=271, Percent_Identity=23.9852398523985, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32613; Mature: 32482

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSQYDFWVKLASRASVATALTLILIKLLAWLYSGSASMLASLTDSFADALASIINFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADHDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEHATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHH
VVSVVAIVLTLALVMLQKRALAATNSTVVEADSLHYKSDLFLNGAVLLALVLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
DGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSAAASS
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TQTSQYDFWVKLASRASVATALTLILIKLLAWLYSGSASMLASLTDSFADALASIINFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADHDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLLNPAPVEHATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHH
VVSVVAIVLTLALVMLQKRALAATNSTVVEADSLHYKSDLFLNGAVLLALVLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
DGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGKTIFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVQVEPSAAASS
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA