Click here to switch to the map view.

The map label for this gene is acoR [H]

Identifier: 117918708

GI number: 117918708

Start: 282029

End: 283915

Strand: Direct

Name: acoR [H]

Synonym: Shewana3_0251

Alternate gene names: 117918708

Gene position: 282029-283915 (Clockwise)

Preceding gene: 117918706

Following gene: 117918711

Centisome position: 5.67

GC content: 53.05

Gene sequence:

>1887_bases
ATGGAGCAGCGCTCGGGGAGCTTGGCTATGACAGTAAAACTGCATTTTCCAACCACACAGGCATGGTTAACCGATTCATG
GCAGCGCAGCTTAGGTGCTGGCTTGTCAGAGTTTCGTGCCGGTGAGGATCTCAGGCTCACGCGTTCGGAGCTCAAATATA
AACATGAGCAATATCAGCAGCTCATCGAATTAGTACAATCCCACGCCTTGCCGCTATTTAATCAACTGATGGCGCACTCT
AATAGTCGATTATTGCTCTCCGATGCCGACGGTTATGTGCTGAAACATTGGGGGGTGAGCCGCTATTCCAGCAAGCTGGC
GGATGTGGCGCTCGATATTGGGGTCAACTGGCTCGAAAAGTATAAGGGCACCAATGCAATAGGCACAGCGCTCACGGCCA
AGCAGGCGGTGTCAGTGGTCGGCGAGCAGCATTTTATCCGCCAAAACCGTTTTATGAGTTGCACCGCTTGCCCGATTTTT
TCGCCCCAAGGTGAGATGCTCGGAGTGCTTGATATTACCAGTGAGCAGCAACGGCATTCGCAGCAAACCTTAATGCTAGT
GTCGAGTCTGGCGCAGCAGGTCGAAACGGCGCTGCTGTGTCATCTACCCGATAGTCATTATCGAATCGATTTCGCGGCGC
AGCCGAGTCTATTAAATTCCGGCTGGCAAGGCATAGTTATCGCTAGCAGTGACGGGCGGATTGTGGGTTGTAATCCCATG
GCGAAACAACTGCTGAGCCAAGCCAAGTTGGGTGACAGTTTAGATCAACACCTCGGCGACAATTGGGCGCGAGCGGGGGG
CTTTCATCGCGATTCGGCGCTGCATGTGCAGACGCAAGCATTGGCACTGACGCAGACGAAAAGTACCAGAACCCTTCAAG
ATAAACCCTTGAACCAATTGGGTGTCAGGTTTCGTGACCCATTACTTGAGCGTGCCTGGCAGCAGGCGAACAAGGTGATC
ACTAAGCAAATTCCTTTACTTGTGCTTGGCGAAACGGGTGTCGGTAAGGAGCAATTTGTGAAAAAGCTCCACGCCCAGAG
TACCCGCCGCGCACAGCCCATAGTTGCAGTAAATTGCGCCGCCTTGCCCGCTGAGTTAGTTGAGTCTGAGTTATTTGGCT
ATCAGGCGGGAGCTTTTACTGGCGCCAATCGAACTGGTTTTATCGGTAAGATCCGCCAGGCACACGGCGGCTTTTTGTTC
CTCGATGAAATTGGCGAGATGCCGCTAGCGGCGCAGAGTCGTTTACTCCGGGTGCTACAGGAGCGCGAGGTGGTCCCCGT
CGGCAGTAATCAAAGTTTTAAGGTCGATATTCAGATCATCGCCGCGACCCATATGGACTTAGAGTCGCTGGTGGCGCAGG
GGTTGTTCCGTCAGGATTTGTTTTATCGCCTGAATGGATTGCAGGTGCGGCTGCCTGCGCTGCGTGAGCGGCAGGATATT
GAGCGCATCATCCATAAATTGCACCGCCGTCACCGCAGCAGCGCGCAAACCTTGTGTACTGAGCTGTTGGCGCAACTGAT
GCGTTACGATTGGCCCGGCAACCTAAGGGAGCTGGATAATCTGATGCAGGTGGCTTGTTTGATGGCCGAAGGTGAAGCTG
TACTCGAGATCAATCATCTCCCCGATTACCTTGCTCAAAAGCTAATGAATCTGGCGTGTGAGCCCCAAACTTTAACTGAG
GTTGCTGACGCAGAAGCTACGGCGCATCCGCACGAGCTGGTTGAGTCTAGCTCCGTCACCATCGACTCGCTCCACGGAAC
CATTAATCTGAATGTGTTGCAGGCTTACCGTGCCTGCGATGGCAATGTGAGCCAATGCGCCAAGCGTTTGGGGATTAGCC
GTAATGCCTTGTATCGCAAGTTAAAACAGCTAGGGATTAAGGATTAA

Upstream 100 bases:

>100_bases
AAAGCTAATTTTGCAGATCCCAAACAATAGGGGCGCTCACGGAAGGAAAGGTGCCCTGTGGTCATTTTGTCATCCAACGA
CACACCATGGGTGTGCCGAA

Downstream 100 bases:

>100_bases
CGGCAGTTGACTGTTGATGATATAAGCCCCGCTAACTGTGTTAGCGAGCCTTATGTTTTTAGGTTGGTAAACTGATATTG
ACTTCAAGGCCGTGGGGCTG

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MEQRSGSLAMTVKLHFPTTQAWLTDSWQRSLGAGLSEFRAGEDLRLTRSELKYKHEQYQQLIELVQSHALPLFNQLMAHS
NSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIF
SPQGEMLGVLDITSEQQRHSQQTLMLVSSLAQQVETALLCHLPDSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPM
AKQLLSQAKLGDSLDQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPLNQLGVRFRDPLLERAWQQANKVI
TKQIPLLVLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLF
LDEIGEMPLAAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDI
ERIIHKLHRRHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLACEPQTLTE
VADAEATAHPHELVESSSVTIDSLHGTINLNVLQAYRACDGNVSQCAKRLGISRNALYRKLKQLGIKD

Sequences:

>Translated_628_residues
MEQRSGSLAMTVKLHFPTTQAWLTDSWQRSLGAGLSEFRAGEDLRLTRSELKYKHEQYQQLIELVQSHALPLFNQLMAHS
NSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIF
SPQGEMLGVLDITSEQQRHSQQTLMLVSSLAQQVETALLCHLPDSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPM
AKQLLSQAKLGDSLDQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPLNQLGVRFRDPLLERAWQQANKVI
TKQIPLLVLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLF
LDEIGEMPLAAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDI
ERIIHKLHRRHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLACEPQTLTE
VADAEATAHPHELVESSSVTIDSLHGTINLNVLQAYRACDGNVSQCAKRLGISRNALYRKLKQLGIKD
>Mature_628_residues
MEQRSGSLAMTVKLHFPTTQAWLTDSWQRSLGAGLSEFRAGEDLRLTRSELKYKHEQYQQLIELVQSHALPLFNQLMAHS
NSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEKYKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIF
SPQGEMLGVLDITSEQQRHSQQTLMLVSSLAQQVETALLCHLPDSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPM
AKQLLSQAKLGDSLDQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPLNQLGVRFRDPLLERAWQQANKVI
TKQIPLLVLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLF
LDEIGEMPLAAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDI
ERIIHKLHRRHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLACEPQTLTE
VADAEATAHPHELVESSSVTIDSLHGTINLNVLQAYRACDGNVSQCAKRLGISRNALYRKLKQLGIKD

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=499, Percent_Identity=31.6633266533066, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1790437, Length=331, Percent_Identity=37.7643504531722, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=41.6167664670659, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1788905, Length=327, Percent_Identity=37.9204892966361, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1788550, Length=325, Percent_Identity=40, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=346, Percent_Identity=38.4393063583815, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786524, Length=403, Percent_Identity=35.7320099255583, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789087, Length=322, Percent_Identity=37.888198757764, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787583, Length=327, Percent_Identity=35.1681957186544, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87082152, Length=334, Percent_Identity=35.0299401197605, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI87081872, Length=205, Percent_Identity=41.9512195121951, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789828, Length=282, Percent_Identity=36.5248226950355, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081858, Length=598, Percent_Identity=24.5819397993311, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69944; Mature: 69944

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRSGSLAMTVKLHFPTTQAWLTDSWQRSLGAGLSEFRAGEDLRLTRSELKYKHEQYQQ
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LIELVQSHALPLFNQLMAHSNSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEK
HHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHH
YKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVLDITSEQQRHS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHH
QQTLMLVSSLAQQVETALLCHLPDSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCEEEEECCCCCEEECCHH
AKQLLSQAKLGDSLDQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPLNQL
HHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCEEEEEHHHHEEECCCCCCCHHCCCHHHH
GVRFRDPLLERAWQQANKVITKQIPLLVLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCA
CCHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECH
ALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQ
HCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHH
EREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDI
HCCCEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
ERIIHKLHRRHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
PDYLAQKLMNLACEPQTLTEVADAEATAHPHELVESSSVTIDSLHGTINLNVLQAYRACD
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCEEEEHHHHHHHHCC
GNVSQCAKRLGISRNALYRKLKQLGIKD
CCHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQRSGSLAMTVKLHFPTTQAWLTDSWQRSLGAGLSEFRAGEDLRLTRSELKYKHEQYQQ
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LIELVQSHALPLFNQLMAHSNSRLLLSDADGYVLKHWGVSRYSSKLADVALDIGVNWLEK
HHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHH
YKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVLDITSEQQRHS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHH
QQTLMLVSSLAQQVETALLCHLPDSHYRIDFAAQPSLLNSGWQGIVIASSDGRIVGCNPM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCEEEEECCCCCEEECCHH
AKQLLSQAKLGDSLDQHLGDNWARAGGFHRDSALHVQTQALALTQTKSTRTLQDKPLNQL
HHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCEEEEEHHHHEEECCCCCCCHHCCCHHHH
GVRFRDPLLERAWQQANKVITKQIPLLVLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCA
CCHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECH
ALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQ
HCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHH
EREVVPVGSNQSFKVDIQIIAATHMDLESLVAQGLFRQDLFYRLNGLQVRLPALRERQDI
HCCCEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
ERIIHKLHRRHRSSAQTLCTELLAQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
PDYLAQKLMNLACEPQTLTEVADAEATAHPHELVESSSVTIDSLHGTINLNVLQAYRACD
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCEEEEHHHHHHHHCC
GNVSQCAKRLGISRNALYRKLKQLGIKD
CCHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]