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The map label for this gene is merD [H]

Identifier: 117676248

GI number: 117676248

Start: 199403

End: 199837

Strand: Reverse

Name: merD [H]

Synonym: Shewana3_4309

Alternate gene names: 117676248

Gene position: 199837-199403 (Counterclockwise)

Preceding gene: 117676249

Following gene: 117676247

Centisome position: 71.64

GC content: 54.02

Gene sequence:

>435_bases
ATGTCAAAAGCCGCCGTGTCAAAAGATGTGTCACGATACTTTGAGGTGATCCCCGACTTTGCGGCATTCATGGATGCCGA
TGGGCAGGCACTCGAATTTCCCCTGACGATCTCGCAACTGGCGAAAGCCGCGCAAACCACAGTGCATACCGTCAGGAATT
ACGTCTTGGAAAATTTGGTACTTTGCCCAGAGCATTCCGCGGGTGGTTTCGGTTTATACAATCAATGCGCTTTAAACCGG
CTGCGCTTCATTCGCGCAGCGCGTGCGGCGGGCCTGCTGATCCTGGATATAAAACCCTTGCTCTACGCCATCAACGAAGG
CGACCAGCAAGCCTGTGAAGCCGCCATGCGCGAACTGCAAACCAAAATTGATGAACGCCAGGCTTACTTGCAGGCATTGG
ATTCACAGCTGTCGGAGCTGCGCCAACTGGCCTGA

Upstream 100 bases:

>100_bases
GATGTATTACAGGGCTATCGGCTGGCGCGGCCAGCCGATGCCGAAACGACTGAAGCGTTGTGGCCAGGCCGCAGTGTTTG
AAACGAACGGAGACAAACCC

Downstream 100 bases:

>100_bases
TCGCCATAACAAAGGAGTATACGATGTCAGAAAAATGTGAAACCGGCCCCCACGACTGGGTAGCCAATAAAGGCCGATTT
ATTCTCACCTGGGTATTGCC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Mercuric resistance protein merD [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSKAAVSKDVSRYFEVIPDFAAFMDADGQALEFPLTISQLAKAAQTTVHTVRNYVLENLVLCPEHSAGGFGLYNQCALNR
LRFIRAARAAGLLILDIKPLLYAINEGDQQACEAAMRELQTKIDERQAYLQALDSQLSELRQLA

Sequences:

>Translated_144_residues
MSKAAVSKDVSRYFEVIPDFAAFMDADGQALEFPLTISQLAKAAQTTVHTVRNYVLENLVLCPEHSAGGFGLYNQCALNR
LRFIRAARAAGLLILDIKPLLYAINEGDQQACEAAMRELQTKIDERQAYLQALDSQLSELRQLA
>Mature_143_residues
SKAAVSKDVSRYFEVIPDFAAFMDADGQALEFPLTISQLAKAAQTTVHTVRNYVLENLVLCPEHSAGGFGLYNQCALNRL
RFIRAARAAGLLILDIKPLLYAINEGDQQACEAAMRELQTKIDERQAYLQALDSQLSELRQLA

Specific function: Zinc-Responsive Transcriptional Regulator Of Znta. [C]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011797 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 15962; Mature: 15831

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAAVSKDVSRYFEVIPDFAAFMDADGQALEFPLTISQLAKAAQTTVHTVRNYVLENLV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LCPEHSAGGFGLYNQCALNRLRFIRAARAAGLLILDIKPLLYAINEGDQQACEAAMRELQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHH
TKIDERQAYLQALDSQLSELRQLA
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKAAVSKDVSRYFEVIPDFAAFMDADGQALEFPLTISQLAKAAQTTVHTVRNYVLENLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LCPEHSAGGFGLYNQCALNRLRFIRAARAAGLLILDIKPLLYAINEGDQQACEAAMRELQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHH
TKIDERQAYLQALDSQLSELRQLA
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8302940; 9159519 [H]