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The map label for this gene is tlpC [H]

Identifier: 117676244

GI number: 117676244

Start: 192443

End: 193609

Strand: Reverse

Name: tlpC [H]

Synonym: Shewana3_4305

Alternate gene names: 117676244

Gene position: 193609-192443 (Counterclockwise)

Preceding gene: 117676245

Following gene: 117676243

Centisome position: 69.41

GC content: 34.96

Gene sequence:

>1167_bases
ATGCGTTCATTATTTATTCGCATGAGGTTTATCCATTGGTTAGGTGCTATTGTACTTTTCATGAATGCAACCTTTTTCAC
AGATCTAATATTTTCACAGATCATTCAGTACATTATTACAATATTTTTGATTATTCATGATATTGATGAAAAAGTTTGGG
GAGTTGACTCCTTAAAAAAAGTTACCGAATACATGAAACACTTTGAAAGAAAAGATCTTTCAGTTCCATGTACCATCAAT
AGCTTATATAACAGTGAAATGGAAAAAGTTCTTAGTGTTATCAATACATTTAGAGAAAATGTAAAAATTGCACTAATCGA
TATTCAGCAACAGGCCATAGCTTCTGATGAAATATCAGATCTTCTAAAAGTTAAAGCGCAAAATATTTCATCGCGTATCA
ATGAGCAAGATAATCGGGTCAGTATTCTCACTTCACAAATAGAGGCCTTAGATCAAACCTCTCTAGCATTACAAGCTAAA
GCAGAAAAAACACGTGAACAAGTAGAAAATACGCAAATAGGGCTTGTTCGATCAAACGAATATATGGGGGCTATGGTTAA
AGATTTAAGCTCGTTTATTGCAAGTAATGATGAACTCCAAGAAAAATTTTATCAACTTTCTCAACAAACAAAAGCCATTG
AGGGAGTGGTATCCGTTATTAATAACCTAGCCGATCAAACCAATCTATTGGCTTTAAATGCTGCCATTGAAGCCGCTAGG
GCTGGAGAGCATGGACGAGGCTTTGCCGTTGTTGCCGATGAGGTCAGAAATCTAGCCAAATCAACCCAAAGTAGTTTAGA
TGAAATTAATCAAATTATATCAGGAATATCTAAAGCGGTTCTTGATGCTGGTCATCATATGAAATCACAAACATCTGCAA
TTGTTCTACTATCGGATTACACAACAACGAGCCAGTCAGAATTAGGCGTTGCATGTAAAAACATCAGTGAAATTTTAACT
TTGATTGGGCAAGATAGAACAAATAATAATTTGGATATCCTCTATGTAAATAGATTAGTTGGTGATGTAAGTAAGGAAAT
TGAGGTGCTAAAACACCTCTCAAGCTCCAACTCAAATGATTGCATCGAATTAGAGCAGCAGGGCCATAGCTTAACTCAAG
TTACTGAAAAAATTGTTCGCCAATTAGGGATGTTTAAAACTAAATAG

Upstream 100 bases:

>100_bases
TGAATATTTTAGATCACGCCTAAATGATATTATTTGTCAGCTAATTTTAAAAGTATATTCAAACTTTTAAAAAAGATACT
ACGAAAACATAGAGGAAAAT

Downstream 100 bases:

>100_bases
TAGCATAACTTAAAGTGCCCAATTGGGTTGACCAGAACAACTTTCCTTGCATTAAAGGAAAATTCTAGAAGACTAAAAAT
AACTACTTCATTCCAAAAGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRSLFIRMRFIHWLGAIVLFMNATFFTDLIFSQIIQYIITIFLIIHDIDEKVWGVDSLKKVTEYMKHFERKDLSVPCTIN
SLYNSEMEKVLSVINTFRENVKIALIDIQQQAIASDEISDLLKVKAQNISSRINEQDNRVSILTSQIEALDQTSLALQAK
AEKTREQVENTQIGLVRSNEYMGAMVKDLSSFIASNDELQEKFYQLSQQTKAIEGVVSVINNLADQTNLLALNAAIEAAR
AGEHGRGFAVVADEVRNLAKSTQSSLDEINQIISGISKAVLDAGHHMKSQTSAIVLLSDYTTTSQSELGVACKNISEILT
LIGQDRTNNNLDILYVNRLVGDVSKEIEVLKHLSSSNSNDCIELEQQGHSLTQVTEKIVRQLGMFKTK

Sequences:

>Translated_388_residues
MRSLFIRMRFIHWLGAIVLFMNATFFTDLIFSQIIQYIITIFLIIHDIDEKVWGVDSLKKVTEYMKHFERKDLSVPCTIN
SLYNSEMEKVLSVINTFRENVKIALIDIQQQAIASDEISDLLKVKAQNISSRINEQDNRVSILTSQIEALDQTSLALQAK
AEKTREQVENTQIGLVRSNEYMGAMVKDLSSFIASNDELQEKFYQLSQQTKAIEGVVSVINNLADQTNLLALNAAIEAAR
AGEHGRGFAVVADEVRNLAKSTQSSLDEINQIISGISKAVLDAGHHMKSQTSAIVLLSDYTTTSQSELGVACKNISEILT
LIGQDRTNNNLDILYVNRLVGDVSKEIEVLKHLSSSNSNDCIELEQQGHSLTQVTEKIVRQLGMFKTK
>Mature_388_residues
MRSLFIRMRFIHWLGAIVLFMNATFFTDLIFSQIIQYIITIFLIIHDIDEKVWGVDSLKKVTEYMKHFERKDLSVPCTIN
SLYNSEMEKVLSVINTFRENVKIALIDIQQQAIASDEISDLLKVKAQNISSRINEQDNRVSILTSQIEALDQTSLALQAK
AEKTREQVENTQIGLVRSNEYMGAMVKDLSSFIASNDELQEKFYQLSQQTKAIEGVVSVINNLADQTNLLALNAAIEAAR
AGEHGRGFAVVADEVRNLAKSTQSSLDEINQIISGISKAVLDAGHHMKSQTSAIVLLSDYTTTSQSELGVACKNISEILT
LIGQDRTNNNLDILYVNRLVGDVSKEIEVLKHLSSSNSNDCIELEQQGHSLTQVTEKIVRQLGMFKTK

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=282, Percent_Identity=26.241134751773, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788195, Length=77, Percent_Identity=51.9480519480519, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787690, Length=174, Percent_Identity=33.9080459770115, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789453, Length=180, Percent_Identity=36.1111111111111, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788194, Length=69, Percent_Identity=55.0724637681159, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 43444; Mature: 43444

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLFIRMRFIHWLGAIVLFMNATFFTDLIFSQIIQYIITIFLIIHDIDEKVWGVDSLKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VTEYMKHFERKDLSVPCTINSLYNSEMEKVLSVINTFRENVKIALIDIQQQAIASDEISD
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
LLKVKAQNISSRINEQDNRVSILTSQIEALDQTSLALQAKAEKTREQVENTQIGLVRSNE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
YMGAMVKDLSSFIASNDELQEKFYQLSQQTKAIEGVVSVINNLADQTNLLALNAAIEAAR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEHGRGFAVVADEVRNLAKSTQSSLDEINQIISGISKAVLDAGHHMKSQTSAIVLLSDY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
TTTSQSELGVACKNISEILTLIGQDRTNNNLDILYVNRLVGDVSKEIEVLKHLSSSNSND
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
CIELEQQGHSLTQVTEKIVRQLGMFKTK
CCHHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRSLFIRMRFIHWLGAIVLFMNATFFTDLIFSQIIQYIITIFLIIHDIDEKVWGVDSLKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VTEYMKHFERKDLSVPCTINSLYNSEMEKVLSVINTFRENVKIALIDIQQQAIASDEISD
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
LLKVKAQNISSRINEQDNRVSILTSQIEALDQTSLALQAKAEKTREQVENTQIGLVRSNE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
YMGAMVKDLSSFIASNDELQEKFYQLSQQTKAIEGVVSVINNLADQTNLLALNAAIEAAR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEHGRGFAVVADEVRNLAKSTQSSLDEINQIISGISKAVLDAGHHMKSQTSAIVLLSDY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
TTTSQSELGVACKNISEILTLIGQDRTNNNLDILYVNRLVGDVSKEIEVLKHLSSSNSND
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
CIELEQQGHSLTQVTEKIVRQLGMFKTK
CCHHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]