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The map label for this gene is dal

Identifier: 116872288

GI number: 116872288

Start: 902287

End: 903393

Strand: Direct

Name: dal

Synonym: lwe0868

Alternate gene names: 116872288

Gene position: 902287-903393 (Clockwise)

Preceding gene: 116872287

Following gene: 116872289

Centisome position: 32.06

GC content: 40.92

Gene sequence:

>1107_bases
ATGGTGACAGGCTGGCATCGTCCGACATGGATTGAAATAGACCGTGAAGCAATTCGCGCAAATATAAAAAATGAGCAACA
TCGTTTACCAGAAAATGTGGCGTTATGGGCAGTTGTAAAAGCCAATGCGTATGGTCATGGTATTATCGAAACCGCAAAGA
CAGCAAAAGAAGCAGGAGCCAAAGGTTTCTGTGTGGCTATTCTTGACGAAGCACTGGCACTTAGAGAAGCTGGATTTCGG
AATGATTTTATTCTCGTCTTAGGTGCAACGCGACAAGAAGACGCAAATCTCGCAGCAAAAAACAATATTTCACTCACTGT
TTTTAGAGAAGATTGGCTTCATAACCTTACACTAGAAGCGCCACTTCGAATCCATTTAAAAGTGGATAGTGGTATGGGAC
GACTTGGTATTCGTAGCACAGAAGAAGCAAAACAAATAGAAGCCAGAATAGCTTTAGATCACCAATTGATTTTAGAAGGA
ATCTATACACATTTTGCGACAGCAGACCAATTAGAAACTAGTTATTTCGAACAACAATTAGATAAATTCACTACTATTTT
AACTAGCTTTGAATCACGTCCGACATTTGTTCATACTGCCAATTCAGCGGCTTCTTTATTACAACCACAAATGGACTTTG
ATGCAGTACGCTTTGGGATTTCAATGTATGGTTTAACGCCTTCTCTTGAAATAAAGAATAGTTTGCCATTCGAGCTCAAA
CCTGCACTTGCACTTTATACGGAAATGGTTCATGTGAAAGAACTTGCGCCAGGTGATAGTGTTAGCTACGGCGCGACCTA
TACAGCAACTGAAAAAGAGTGGGTAGCGACTTTGCCGATTGGCTATGCGGATGGGTTAATTCGTCACTATAGCGGATATC
ATGTGTTAGTGGACGGAGAACTTGCTCCAATCATCGGAAGGGTCTGCATGGACCAAACAATTATAAAACTTCCTCGTGAA
TTTCAAACTGGTTCAAAAGTAACGATAATTGGCACGGATCACGGAAATACAATAACAGCAGACGACGCCGCTGATTACTT
AGGTACAATTAATTACGAAGTTACCTGCTTGTTATCTGACCGCATACCAAGGAAATACATCAATTAG

Upstream 100 bases:

>100_bases
GATAAAATCAGGGGAAACGGTTTTTGTGAGCATCACGCATACAGCCAGATCAGCCGCAGCCCAAGTGATAATTGAAATAT
AGAAAGGAAAGTGAATGATT

Downstream 100 bases:

>100_bases
AAGCTAATATTCGTGCTTTTTTTAAGAGAAGCGTTTATAATCTAACATATGAAACTTTATAGCTATATATAGGACTTAAG
GGAGCGCTATAACTAAAACT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGAKGFCVAILDEALALREAGFR
NDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEAPLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEG
IYTHFATADQLETSYFEQQLDKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSDRIPRKYIN

Sequences:

>Translated_368_residues
MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGAKGFCVAILDEALALREAGFR
NDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEAPLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEG
IYTHFATADQLETSYFEQQLDKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSDRIPRKYIN
>Mature_368_residues
MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGAKGFCVAILDEALALREAGFR
NDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEAPLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEG
IYTHFATADQLETSYFEQQLDKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSDRIPRKYIN

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=363, Percent_Identity=33.0578512396694, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787439, Length=370, Percent_Identity=33.2432432432432, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_LISW6 (A0AH04)

Other databases:

- EMBL:   AM263198
- RefSeq:   YP_849069.1
- ProteinModelPortal:   A0AH04
- SMR:   A0AH04
- STRING:   A0AH04
- GeneID:   4465071
- GenomeReviews:   AM263198_GR
- KEGG:   lwe:lwe0868
- NMPDR:   fig|386043.6.peg.840
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   LPRRYLE
- PhylomeDB:   A0AH04
- ProtClustDB:   CLSK564147
- BioCyc:   LWEL386043:LWE0868-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 40948; Mature: 40948

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 40-40 ACT_SITE 263-263

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGA
CCCCCCCCEEEEECHHHHHHHCCCHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCC
KGFCVAILDEALALREAGFRNDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEA
CCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCEEEEEECCCHHCCEEEC
PLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEGIYTHFATADQLETSYFEQQL
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELK
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCHHHHHHCEEEECCCCCEEECCCCCCCCC
PALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGE
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCC
LAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSD
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEECCCHHHHHEECCEEEEEEECC
RIPRKYIN
CCCHHHCC
>Mature Secondary Structure
MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGA
CCCCCCCCEEEEECHHHHHHHCCCHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCC
KGFCVAILDEALALREAGFRNDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEA
CCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCEEEEEECCCHHCCEEEC
PLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEGIYTHFATADQLETSYFEQQL
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELK
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCHHHHHHCEEEECCCCCEEECCCCCCCCC
PALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGE
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCC
LAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSD
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEECCCHHHHHEECCEEEEEEECC
RIPRKYIN
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA