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The map label for this gene is acpS [H]

Identifier: 116872287

GI number: 116872287

Start: 901912

End: 902268

Strand: Direct

Name: acpS [H]

Synonym: lwe0867

Alternate gene names: 116872287

Gene position: 901912-902268 (Clockwise)

Preceding gene: 116872286

Following gene: 116872288

Centisome position: 32.05

GC content: 38.38

Gene sequence:

>357_bases
ATGATTAAAGGAATTGGACTAGATATGATTGACTTAGAGCGTGTAAAACAAGTACTAGAAAAAAATCCGCGTTTTATTGA
AAGAGTCCTTACTGAAAAAGAAATTAAGCAATTTGAAAAATATGAAGGAAGCCGCAAAATTGAGTTTTTGGCTGGACGCT
TTGCAGCGAAAGAAGCGTATGCGAAAGCAAATGGAACTGGTTTTGGGAAACATTTAAGTTTTACAGATGTGGAAATTTTG
CAAGTGGAAGATGGACGACCACATGTGACAATGCCGATAAAATCAGGGGAAACGGTTTTTGTGAGCATCACGCATACAGC
CAGATCAGCCGCAGCCCAAGTGATAATTGAAATATAG

Upstream 100 bases:

>100_bases
TTTGCAGGTATGAGTTATGAAGGCGTCGGTATTCCCGATTGTATTGCTGGAGCGCAAACTGCGGTTACTGAGCTCACAGA
TATTTTAGAAGAGGTGTCAA

Downstream 100 bases:

>100_bases
AAAGGAAAGTGAATGATTATGGTGACAGGCTGGCATCGTCCGACATGGATTGAAATAGACCGTGAAGCAATTCGCGCAAA
TATAAAAAATGAGCAACATC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MIKGIGLDMIDLERVKQVLEKNPRFIERVLTEKEIKQFEKYEGSRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTMPIKSGETVFVSITHTARSAAAQVIIEI

Sequences:

>Translated_118_residues
MIKGIGLDMIDLERVKQVLEKNPRFIERVLTEKEIKQFEKYEGSRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTMPIKSGETVFVSITHTARSAAAQVIIEI
>Mature_118_residues
MIKGIGLDMIDLERVKQVLEKNPRFIERVLTEKEIKQFEKYEGSRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTMPIKSGETVFVSITHTARSAAAQVIIEI

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=33.6, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 13264; Mature: 13264

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGIGLDMIDLERVKQVLEKNPRFIERVLTEKEIKQFEKYEGSRKIEFLAGRFAAKEAY
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
AKANGTGFGKHLSFTDVEILQVEDGRPHVTMPIKSGETVFVSITHTARSAAAQVIIEI
HCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHEEEEEC
>Mature Secondary Structure
MIKGIGLDMIDLERVKQVLEKNPRFIERVLTEKEIKQFEKYEGSRKIEFLAGRFAAKEAY
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
AKANGTGFGKHLSFTDVEILQVEDGRPHVTMPIKSGETVFVSITHTARSAAAQVIIEI
HCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]