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The map label for this gene is rhtC [H]

Identifier: 116690007

GI number: 116690007

Start: 2202537

End: 2203166

Strand: Direct

Name: rhtC [H]

Synonym: Bcen2424_1986

Alternate gene names: 116690007

Gene position: 2202537-2203166 (Clockwise)

Preceding gene: 116690006

Following gene: 116690008

Centisome position: 63.22

GC content: 65.56

Gene sequence:

>630_bases
ATGATCGCCAGTCAGATCGCACTCGTCTACGGCACCTATCTCGTCGCCACAGCCAGCCCCGGGCCGAGCAACATGGCGAT
CATGGCAACAGCGATGCGTGACGGCCGTCTGCCGGCCCTCGTGCTGGCCGCCGGCGTCATCACGGGCTCGCTCTTCTGGG
CGATCCTGGCGGCGACCGGCGTTTCCGCCGTGCTGGCGGCCTATGCCGAGGCACTCGTCGTGATCAAGATGGTTGGCGGT
GTCTATCTGCTCTACCTGGCGTTCCGCACGGGCAGGTCGGCGCTGAAACCGGGCCCCGGCTTCGCGAAGATGGAACCCGG
ACGCCCGACACCGCCCTATCGGCGACTCTACCGTCAGGGCATTCTCATGCATATCGGAAACCCGAAGGCGGTTCTGGCCT
GGATGGCCATCATGTCCCTCGGGCTTCAGGAACACGCGTCCGGCGGCACCTTGCCGGCGATCATCGGCGGTTGCGCGCTC
CTCGGCGTCATCGTGTTTGGCGGTTATGCGGTCCTCTTCTCGACCGCTCGGATGATCGCCGTGTATGCCCGCCTCCGGCG
CTGGATTGAAGGCACGCTATCCGCGGTGTTCGCCGTTGCGGGAGTCAACCTGCTTGCCTGGCAACGTTGA

Upstream 100 bases:

>100_bases
GCGTATCTGCGCGACCCTGACGGGAACAAGGTCCATATCGTTCATCGCGGGGATCTCCAGCCGTGACGCTGGAGACACTC
GCCTCTCTGGAGAACCTCGA

Downstream 100 bases:

>100_bases
TATCCCGGCTCGCCGGCGCCGTCACGAACTGATCTGAATTGAAAGAGCGATGTCATGAGCTTTGCGATCCATATGGTCGA
CGTCTTCGGCGCCGAACCGC

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIASQIALVYGTYLVATASPGPSNMAIMATAMRDGRLPALVLAAGVITGSLFWAILAATGVSAVLAAYAEALVVIKMVGG
VYLLYLAFRTGRSALKPGPGFAKMEPGRPTPPYRRLYRQGILMHIGNPKAVLAWMAIMSLGLQEHASGGTLPAIIGGCAL
LGVIVFGGYAVLFSTARMIAVYARLRRWIEGTLSAVFAVAGVNLLAWQR

Sequences:

>Translated_209_residues
MIASQIALVYGTYLVATASPGPSNMAIMATAMRDGRLPALVLAAGVITGSLFWAILAATGVSAVLAAYAEALVVIKMVGG
VYLLYLAFRTGRSALKPGPGFAKMEPGRPTPPYRRLYRQGILMHIGNPKAVLAWMAIMSLGLQEHASGGTLPAIIGGCAL
LGVIVFGGYAVLFSTARMIAVYARLRRWIEGTLSAVFAVAGVNLLAWQR
>Mature_209_residues
MIASQIALVYGTYLVATASPGPSNMAIMATAMRDGRLPALVLAAGVITGSLFWAILAATGVSAVLAAYAEALVVIKMVGG
VYLLYLAFRTGRSALKPGPGFAKMEPGRPTPPYRRLYRQGILMHIGNPKAVLAWMAIMSLGLQEHASGGTLPAIIGGCAL
LGVIVFGGYAVLFSTARMIAVYARLRRWIEGTLSAVFAVAGVNLLAWQR

Specific function: Conducts the efflux of threonine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786522, Length=142, Percent_Identity=24.6478873239437, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21952; Mature: 21952

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASQIALVYGTYLVATASPGPSNMAIMATAMRDGRLPALVLAAGVITGSLFWAILAATG
CCHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VSAVLAAYAEALVVIKMVGGVYLLYLAFRTGRSALKPGPGFAKMEPGRPTPPYRRLYRQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
ILMHIGNPKAVLAWMAIMSLGLQEHASGGTLPAIIGGCALLGVIVFGGYAVLFSTARMIA
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYARLRRWIEGTLSAVFAVAGVNLLAWQR
HHHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MIASQIALVYGTYLVATASPGPSNMAIMATAMRDGRLPALVLAAGVITGSLFWAILAATG
CCHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VSAVLAAYAEALVVIKMVGGVYLLYLAFRTGRSALKPGPGFAKMEPGRPTPPYRRLYRQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
ILMHIGNPKAVLAWMAIMSLGLQEHASGGTLPAIIGGCALLGVIVFGGYAVLFSTARMIA
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYARLRRWIEGTLSAVFAVAGVNLLAWQR
HHHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]