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The map label for this gene is argE [H]

Identifier: 116689966

GI number: 116689966

Start: 2162798

End: 2164018

Strand: Direct

Name: argE [H]

Synonym: Bcen2424_1945

Alternate gene names: 116689966

Gene position: 2162798-2164018 (Clockwise)

Preceding gene: 116689965

Following gene: 116689967

Centisome position: 62.08

GC content: 67.73

Gene sequence:

>1221_bases
ATGTCCACTCTCGACGCGACGGCGCCGTCCGCCGCAACCGAAGGCGATGCATCGCTCGTCAGCCTGCCCTGGGTCAAGCA
ACTCGTGTCGATGGACACGACGAGCCGCGTGCCGAACCTCGGCCTGATCGAAACGGTACGCGACGCGCTCGCCGCGAAGG
GCATCGCGTCGACGATCACGCACGATCCGCGTGAAGGCTGGGCGAACCTGTTTGCCACCGTGCCCGCGCACGACGGTTCG
ACGAACGGCGGCATCGTGCTGTCGGGCCACACCGACGTCGTGCCGGTCGACGGCCAGCAATGGGACAGCAACCCGTTCGC
GCCGGAAATCCGCGACGGCCGCCTGTACGGCCGCGGCACCTGCGACATGAAGGGCTTCATCGGCGCGGCGCTCGCGCTGC
TGCCCGAGATGCAGGCGACGAAGCTCGCGAAGCCGATCCATTTCGCGCTGTCCTACGACGAGGAAATCGGCTGCGCGGGC
GCGCCGCTGATGATCGCCGATCTCGTGAAGCGCGGCGTGCAGCCGTCCGGCTGCATCGTCGGCGAGCCGACCAGCATGCG
GCCGATCATCGCGCACAAGGGCATCAACGCGTACCGCTGCTGCGTGCGCGGCCACGCCGCACATTCGTCGCTGACGCCGA
AGGGGCTCAACGCGATCGAGTATGCGGCGCGCCTGATCTGCCACATCCGCGACATCGCTGAGCGCTTCCGTGCCGAAGGC
CCGTTCGACGAACTGTACGACGTGCCGTTCACCACCGCGCAGACGAGCACGATCCAGGGCGGCAACGCGATCAACACGGT
GCCGGCCGAGTGCCGCTTCGACTTCGAATTCCGCAACCTGCCGACGCTCGATCCCGAGCAGATCTTCACGCGCATCGAAG
CGTATGCGCAGGAAACGCTGCTGCCGCAGATGCTGCGCGAACATCCGAACGCCGCGATCGAATTCTCGAAGATCGCCGCG
GCGCCCGGCCTCGACGCGACCGAGCAAGCCGCGATCACGCAGCTCGTGCGCGCGCTGACGGCCGACCAGGACAAGCGCAA
GGTCGCGTACGGCACCGAGGCCGGGCTGTTCGCCCGCGCGGGCATTCCGAGCGTCGTGTGCGGGCCCGGCAACATCGAGC
AGGCGCACAAGCCGAACGAATATGTCGAGCTCGCGCAGCTCGCCGGCTGCGAGCAGTTCCTGCGCAAGTTCATTCGCAGC
ATGTCGGTCGACCCGCACTGA

Upstream 100 bases:

>100_bases
ATCCTGACGGGCGCGACGTTGCTGCACCGCATCGCGCCCGACGAAGGCGGGCAGGCGCGTTTTTGAGTATGATTTCCCAT
TCATCAGACGGAGTTTTGCC

Downstream 100 bases:

>100_bases
CTGCCTCCCGCCACGCCGGCCCGCGTGTGCGGGTCGGCCCACTCCGCCACCCGCCACGTCATGTCGACTGAACAACAGGG
CACTGCCCATACGACGATCG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSTLDATAPSAATEGDASLVSLPWVKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGS
TNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGAALALLPEMQATKLAKPIHFALSYDEEIGCAG
APLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIAERFRAEG
PFDELYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYAQETLLPQMLREHPNAAIEFSKIAA
APGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFARAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRS
MSVDPH

Sequences:

>Translated_406_residues
MSTLDATAPSAATEGDASLVSLPWVKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGS
TNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGAALALLPEMQATKLAKPIHFALSYDEEIGCAG
APLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIAERFRAEG
PFDELYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYAQETLLPQMLREHPNAAIEFSKIAA
APGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFARAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRS
MSVDPH
>Mature_405_residues
STLDATAPSAATEGDASLVSLPWVKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTITHDPREGWANLFATVPAHDGST
NGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGTCDMKGFIGAALALLPEMQATKLAKPIHFALSYDEEIGCAGA
PLMIADLVKRGVQPSGCIVGEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIAERFRAEGP
FDELYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYAQETLLPQMLREHPNAAIEFSKIAAA
PGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFARAGIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSM
SVDPH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=363, Percent_Identity=31.6804407713499, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788816, Length=336, Percent_Identity=27.9761904761905, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43671; Mature: 43540

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLDATAPSAATEGDASLVSLPWVKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTIT
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHC
HDPREGWANLFATVPAHDGSTNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGT
CCHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCCC
CDMKGFIGAALALLPEMQATKLAKPIHFALSYDEEIGCAGAPLMIADLVKRGVQPSGCIV
CCHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEE
GEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIAERFRAEG
CCCCCCCCHHHHCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFDELYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYAQETL
CHHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LPQMLREHPNAAIEFSKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFARA
HHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEECC
GIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSMSVDPH
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STLDATAPSAATEGDASLVSLPWVKQLVSMDTTSRVPNLGLIETVRDALAAKGIASTIT
CCCCCCCCCCCCCCCCCEEECHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHC
HDPREGWANLFATVPAHDGSTNGGIVLSGHTDVVPVDGQQWDSNPFAPEIRDGRLYGRGT
CCHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCCC
CDMKGFIGAALALLPEMQATKLAKPIHFALSYDEEIGCAGAPLMIADLVKRGVQPSGCIV
CCHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEE
GEPTSMRPIIAHKGINAYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDIAERFRAEG
CCCCCCCCHHHHCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFDELYDVPFTTAQTSTIQGGNAINTVPAECRFDFEFRNLPTLDPEQIFTRIEAYAQETL
CHHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LPQMLREHPNAAIEFSKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFARA
HHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEECC
GIPSVVCGPGNIEQAHKPNEYVELAQLAGCEQFLRKFIRSMSVDPH
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]