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The map label for this gene is surA [C]

Identifier: 116689933

GI number: 116689933

Start: 2119627

End: 2120409

Strand: Direct

Name: surA [C]

Synonym: Bcen2424_1912

Alternate gene names: 116689933

Gene position: 2119627-2120409 (Clockwise)

Preceding gene: 116689932

Following gene: 116689936

Centisome position: 60.84

GC content: 64.62

Gene sequence:

>783_bases
ATGATCCTGAAATCCCCCCGCCTGTGGGTCGCGGCGGCTGCTTTTGCAGCGGCACCGGCATTCGCCCAGAACATCGCCGT
CGTCAACGGCACGCCGATTCCGAAGTCGCGCGCCGACGCGATGGTCGCGCAGCTCGTCCAGCAAGGCCAGACCGACGGCC
CGCAACTGCAGCAGGCCGTGCGCCAGGAACTGGTGAACCGCGAAATCCTGATGCAGGAAGCGATCCGCGAAGGCATCCCG
AATCGTCCGGACGTGAAGGCGCAAGTCGCCGTCGCGCAGCAGACCGTCGTGCTGCGCTCGATGATCGAGAGCTTCCTGAA
GAAGAACCAGCCGACCGATGCCGAAGTGAAGGCGCGCTATGACGAACTCGTCAAGGGCGTGGGCGGCAACCGCGAGTACC
ACCTGCACCACATCCTCGTCGACAACGAGCAGCAGGCGAAGGACCTGATCGCGAAGATCAAGGGCGGCGCGAAGTTCGAG
GACCTCGCGAAGCAATACTCGAAGGACCCGGGTTCGGGCAAGAACGGCGGCGATCTCGACTGGTCGGACCCGAAGGCGTA
CGTGCCGGAATTCGCGGCAGCCGCGCAGAAGCTGCAGAAAGGCCAGATGACCGACGCGCCGGTGAAGACGCAGTTCGGCT
GGCACATCATCCGCGTCGACGACATCCGCGACATCGCGCCGCCGCCGTTCGACCAGGTGAAGGCGCAGATCGCGCAGCAG
CTCGTGCAGCAGAAGCTGCAGGCGTTCGAGGAAGGTCTGCGTCAGCAGGCGAAGATCCAGTAA

Upstream 100 bases:

>100_bases
CGCTGATGCGATGCAGCGCGGCATTCACGCGCTCGCGATCGTGGCTTACACGCCCGAAGAATTCAACGAATCTTCAATCT
AGTCTCATTAGGAATTCCCG

Downstream 100 bases:

>100_bases
CGCCGGCGCGCGTCATACGCGCATCGAAAAGCCGCTCTTCGGAGCGGCTTTTTCTTTTGACGTGCACGAAACAGATGTAG
CGCGACGCGATGGTGCGTGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MILKSPRLWVAAAAFAAAPAFAQNIAVVNGTPIPKSRADAMVAQLVQQGQTDGPQLQQAVRQELVNREILMQEAIREGIP
NRPDVKAQVAVAQQTVVLRSMIESFLKKNQPTDAEVKARYDELVKGVGGNREYHLHHILVDNEQQAKDLIAKIKGGAKFE
DLAKQYSKDPGSGKNGGDLDWSDPKAYVPEFAAAAQKLQKGQMTDAPVKTQFGWHIIRVDDIRDIAPPPFDQVKAQIAQQ
LVQQKLQAFEEGLRQQAKIQ

Sequences:

>Translated_260_residues
MILKSPRLWVAAAAFAAAPAFAQNIAVVNGTPIPKSRADAMVAQLVQQGQTDGPQLQQAVRQELVNREILMQEAIREGIP
NRPDVKAQVAVAQQTVVLRSMIESFLKKNQPTDAEVKARYDELVKGVGGNREYHLHHILVDNEQQAKDLIAKIKGGAKFE
DLAKQYSKDPGSGKNGGDLDWSDPKAYVPEFAAAAQKLQKGQMTDAPVKTQFGWHIIRVDDIRDIAPPPFDQVKAQIAQQ
LVQQKLQAFEEGLRQQAKIQ
>Mature_260_residues
MILKSPRLWVAAAAFAAAPAFAQNIAVVNGTPIPKSRADAMVAQLVQQGQTDGPQLQQAVRQELVNREILMQEAIREGIP
NRPDVKAQVAVAQQTVVLRSMIESFLKKNQPTDAEVKARYDELVKGVGGNREYHLHHILVDNEQQAKDLIAKIKGGAKFE
DLAKQYSKDPGSGKNGGDLDWSDPKAYVPEFAAAAQKLQKGQMTDAPVKTQFGWHIIRVDDIRDIAPPPFDQVKAQIAQQ
LVQQKLQAFEEGLRQQAKIQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=98, Percent_Identity=37.7551020408163, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786238, Length=104, Percent_Identity=41.3461538461538, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537235, Length=98, Percent_Identity=38.7755102040816, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28700; Mature: 28700

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKSPRLWVAAAAFAAAPAFAQNIAVVNGTPIPKSRADAMVAQLVQQGQTDGPQLQQAV
CCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
RQELVNREILMQEAIREGIPNRPDVKAQVAVAQQTVVLRSMIESFLKKNQPTDAEVKARY
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DELVKGVGGNREYHLHHILVDNEQQAKDLIAKIKGGAKFEDLAKQYSKDPGSGKNGGDLD
HHHHHCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC
WSDPKAYVPEFAAAAQKLQKGQMTDAPVKTQFGWHIIRVDDIRDIAPPPFDQVKAQIAQQ
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHH
LVQQKLQAFEEGLRQQAKIQ
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILKSPRLWVAAAAFAAAPAFAQNIAVVNGTPIPKSRADAMVAQLVQQGQTDGPQLQQAV
CCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
RQELVNREILMQEAIREGIPNRPDVKAQVAVAQQTVVLRSMIESFLKKNQPTDAEVKARY
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DELVKGVGGNREYHLHHILVDNEQQAKDLIAKIKGGAKFEDLAKQYSKDPGSGKNGGDLD
HHHHHCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC
WSDPKAYVPEFAAAAQKLQKGQMTDAPVKTQFGWHIIRVDDIRDIAPPPFDQVKAQIAQQ
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHH
LVQQKLQAFEEGLRQQAKIQ
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]