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The map label for this gene is hflC [H]

Identifier: 116689825

GI number: 116689825

Start: 2004854

End: 2005753

Strand: Reverse

Name: hflC [H]

Synonym: Bcen2424_1804

Alternate gene names: 116689825

Gene position: 2005753-2004854 (Counterclockwise)

Preceding gene: 116689826

Following gene: 116689824

Centisome position: 57.57

GC content: 67.89

Gene sequence:

>900_bases
ATGAACCGAATCATTGCGCTCGTCGTCGCAATCGTGATCGTTGCCTTCGCGGCATCGTCGACGGTCCTGACCGTCGATCC
GCGCCATGCGGCCGTGCTGTCGGGCCGCGACGGTACGCAGCCGGAGCTCGCGGGCCCCGGCGTCCACTTCAAGCTGCCGC
CGCCGCTGCAGACGGCCACGCTGATCGACACGCGCCTGCAGTCGCTCGAGTCGGCCGATCCGCTGCAGCTGGCAACCGAA
GACAAGCATGACCTGCTCGTCGCGTATGCGGTGAAGTACCGGATCAGCGATCCGATGAAATATTTCACGGCGACGGGCGG
CGATCCGGCCGCGGCGGTCGAACGACTGTCGGGCGCGCTGAAGAGCGCGCTCGGCGACGCATTCGGCAAGCGCGCGCTCG
ACGATGCCCTCGGCGGTCAGCGTGCGATCGCCGATGCGGCGCGCGATACGGCGAAGGCGCAAGCGTCCGGTTTCGGCGTC
GACGTCGTCGACGTCCAGCTGACGCGGGTCGACCTGCCGGCCGCGCAGACGGACGCCGTCTATCAACGGATGATCGGCGC
GTTGCGCGACCAGGCGGCCCAGGTGCGTGCGCAAGGCGCGGCCGACGTCGAGCAGATCAAGGCCGACGCCGAACGCGAGC
AGCAGGCCGTGCTTGCGAACGCATACAAGTCCGCGCAGACGATCAAGGGCGAGGGCGATGCGAAGGCCGCGACGATCGCC
GCCGATGCGTTCGGCCGCGATCCGCAGTTCTATCAGTTCTACGCGAGCCTGCAGGCCTACCGGAATACGTTCAAGCGCAA
CGACATCATCGTCGTCGATCCCGACAGCGAGTTCTTCCGCTTCATGCGCAGCCCGACGGGCGGTGCCGCACCGGCGGCGC
CTGCTCCCCGCAAACATTGA

Upstream 100 bases:

>100_bases
ACCGGCCGCCACCGCGTCGGGTGTCGACGTGCTGCGATCGCGGGACGCGTTTCGCAGCCGGTCGCGTGAAGACGATACGA
AGTAACGGGGAGCGCAGAAC

Downstream 100 bases:

>100_bases
CCTTGGGGCGCCGCGTCGAGCGGCGCCGTCGCTCGCATGGACCTGGCTGGCTCGTTGTTGCTCGCAGTAGCGCTGATGCT
GATCATCGAGGGGGCGTTCC

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGTQPELAGPGVHFKLPPPLQTATLIDTRLQSLESADPLQLATE
DKHDLLVAYAVKYRISDPMKYFTATGGDPAAAVERLSGALKSALGDAFGKRALDDALGGQRAIADAARDTAKAQASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH

Sequences:

>Translated_299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGTQPELAGPGVHFKLPPPLQTATLIDTRLQSLESADPLQLATE
DKHDLLVAYAVKYRISDPMKYFTATGGDPAAAVERLSGALKSALGDAFGKRALDDALGGQRAIADAARDTAKAQASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
>Mature_299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGTQPELAGPGVHFKLPPPLQTATLIDTRLQSLESADPLQLATE
DKHDLLVAYAVKYRISDPMKYFTATGGDPAAAVERLSGALKSALGDAFGKRALDDALGGQRAIADAARDTAKAQASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=293, Percent_Identity=34.4709897610922, Blast_Score=160, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 31749; Mature: 31749

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGTQPELAGPGVHFKLPPPLQTAT
CHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCCEEECCCCCCHHH
LIDTRLQSLESADPLQLATEDKHDLLVAYAVKYRISDPMKYFTATGGDPAAAVERLSGAL
HHHHHHHHHCCCCCCEECCCCCCCEEEEHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHH
KSALGDAFGKRALDDALGGQRAIADAARDTAKAQASGFGVDVVDVQLTRVDLPAAQTDAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHH
YQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEE
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGTQPELAGPGVHFKLPPPLQTAT
CHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCCEEECCCCCCHHH
LIDTRLQSLESADPLQLATEDKHDLLVAYAVKYRISDPMKYFTATGGDPAAAVERLSGAL
HHHHHHHHHCCCCCCEECCCCCCCEEEEHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHH
KSALGDAFGKRALDDALGGQRAIADAARDTAKAQASGFGVDVVDVQLTRVDLPAAQTDAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHH
YQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEE
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]