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The map label for this gene is 116689715

Identifier: 116689715

GI number: 116689715

Start: 1881582

End: 1881965

Strand: Direct

Name: 116689715

Synonym: Bcen2424_1693

Alternate gene names: NA

Gene position: 1881582-1881965 (Clockwise)

Preceding gene: 116689714

Following gene: 116689716

Centisome position: 54.01

GC content: 62.76

Gene sequence:

>384_bases
ATGGCGCTGATCGACCATCTCGATCATCTCGTGCTGACCTGCGTCGATCCGGAACGGACGAAGCATTTCTACACCGAGGT
GCTGCAGATGCAGCTCGAAACCTTCGGCGCGGGCCGGCTCGCGTTCCGTTTCGGGAACCAGAAGATCAACCTCCACGTGC
GCGGCGCGGAATTCGAGCCGAAAGCGCATGTGCCGGTACCGGGCGCGCTCGACCTGTGCTTCATCGCGTCGGTTCCGCTC
GACGATGTGATCGCGCACCTGCGGCGCGTCGACTGGCCGATCGTGGAAGGGCCCGTCGAACGCACGGGCGCGACACAGAA
GATTCGTTCGGTCTACGTGCGCGATCCCGACCTGAACCTGATCGAAATCTCCGAGCTGATCTGA

Upstream 100 bases:

>100_bases
TCGGACCTTCATTCGCCGCCGCGCGCCGACGCCGGCGACATGCCCGCGCAACGCGCTTTCTCGTGAATCGTGAACCCCAA
CAGGAACAGGAGGGAATCCC

Downstream 100 bases:

>100_bases
CCTGACCTGCCGGGTGCGGCCGCCTGCACGAGCACCCGCACGCTGCGCGCCCGGCGCCACAGTCCTTCGCCGAAAGCGGA
CAGGCACGCGCCGCGCCCGC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MALIDHLDHLVLTCVDPERTKHFYTEVLQMQLETFGAGRLAFRFGNQKINLHVRGAEFEPKAHVPVPGALDLCFIASVPL
DDVIAHLRRVDWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI

Sequences:

>Translated_127_residues
MALIDHLDHLVLTCVDPERTKHFYTEVLQMQLETFGAGRLAFRFGNQKINLHVRGAEFEPKAHVPVPGALDLCFIASVPL
DDVIAHLRRVDWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI
>Mature_126_residues
ALIDHLDHLVLTCVDPERTKHFYTEVLQMQLETFGAGRLAFRFGNQKINLHVRGAEFEPKAHVPVPGALDLCFIASVPLD
DVIAHLRRVDWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=126, Percent_Identity=53.968253968254, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14365; Mature: 14234

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIDHLDHLVLTCVDPERTKHFYTEVLQMQLETFGAGRLAFRFGNQKINLHVRGAEFEP
CCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHVPVPGALDLCFIASVPLDDVIAHLRRVDWPIVEGPVERTGATQKIRSVYVRDPDLNL
CCCCCCCCCHHEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEECCCCCE
IEISELI
EEHHHCC
>Mature Secondary Structure 
ALIDHLDHLVLTCVDPERTKHFYTEVLQMQLETFGAGRLAFRFGNQKINLHVRGAEFEP
CHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHVPVPGALDLCFIASVPLDDVIAHLRRVDWPIVEGPVERTGATQKIRSVYVRDPDLNL
CCCCCCCCCHHEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEECCCCCE
IEISELI
EEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]