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The map label for this gene is kdgR [H]

Identifier: 116689691

GI number: 116689691

Start: 1854948

End: 1855691

Strand: Direct

Name: kdgR [H]

Synonym: Bcen2424_1669

Alternate gene names: 116689691

Gene position: 1854948-1855691 (Clockwise)

Preceding gene: 116689690

Following gene: 116689697

Centisome position: 53.24

GC content: 70.83

Gene sequence:

>744_bases
ATGGACGTCAAACTCGTTGCCCGCACGCTCGACCTGTTCGAGCTGTTCGCCGCCGAACGGCGGCCGCTGCCGCTCACCGA
ACTCGCGCGCCTGCTCAACGTGCCGGCGTCGAGCTGCCTCGCGATGGCGCGCACGCTCGTGAGCCGCGGCTACCTGTACG
AAGTGCGCAAGCGCGGCGGCTACTACCCGACGCGGCGCCTGCAGACGGTCGCCGCCGCGATCGACGCGACCGATCCGGTC
GTCGACATCGTGCATCCGCATCTCGTCGCGCTGCGCGACGCGAGCCGCGAAACCGCCGTGCTCGGCAAGATCCAGGGTGT
GTCGGTCACGTATCTCGACGTCGTCGAATCGGAGCAGGCGATCCGCTATACGCGCCAGCCGGGCGAGCTGCGCCCGCTGC
ACGCGAACTCGATCGGCAAGGCGATCTTCGCGGAACTCGCGAGCGAGGCGCAGCAGGCGCTCGGCGCGCAACTGCCGTTC
GAACGCTTCACCGATGCGACGGTGGCCGACCTGGCGGCGCTCGTCGCGCAGACCGCGCGGTTTCGCGAACTCGGCTGGGC
CGAGAACTTCGGCGAGAGCGCGCCCGAGCTGTCGGCGCTCGCGGTGGCGCTGACGCTCGACGGCGACTGGTACGGGCTGT
CGGTCGTCGGGCCGACCGAGCGGATTCGCCAGCATCGCGACAAGCATGCGGCGCTGCTCGTCGACGCGAAGGCACGGCTG
CTGGCCGAGCACGCGCGCGGGTAG

Upstream 100 bases:

>100_bases
CATCGCGGAGAAGGTGCTCGGGCTGCCGAAGTCGTACTGACCGTAGCGCCCCGGCGGCCCGCCCGGCGCGCGGTTTCCCG
TTCCGAATCAAGCGCTCGTC

Downstream 100 bases:

>100_bases
GGCAGCGGCGCGCGCCGGCATCGGCAGCGGGCCGTTCCGGCGTTCGGTCCTGCCACGCCGGAAACGGCCCGCCGTACGTC
ACGCGCGAGCGCGTCGCAAC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTVAAAIDATDPV
VDIVHPHLVALRDASRETAVLGKIQGVSVTYLDVVESEQAIRYTRQPGELRPLHANSIGKAIFAELASEAQQALGAQLPF
ERFTDATVADLAALVAQTARFRELGWAENFGESAPELSALAVALTLDGDWYGLSVVGPTERIRQHRDKHAALLVDAKARL
LAEHARG

Sequences:

>Translated_247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTVAAAIDATDPV
VDIVHPHLVALRDASRETAVLGKIQGVSVTYLDVVESEQAIRYTRQPGELRPLHANSIGKAIFAELASEAQQALGAQLPF
ERFTDATVADLAALVAQTARFRELGWAENFGESAPELSALAVALTLDGDWYGLSVVGPTERIRQHRDKHAALLVDAKARL
LAEHARG
>Mature_247_residues
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGGYYPTRRLQTVAAAIDATDPV
VDIVHPHLVALRDASRETAVLGKIQGVSVTYLDVVESEQAIRYTRQPGELRPLHANSIGKAIFAELASEAQQALGAQLPF
ERFTDATVADLAALVAQTARFRELGWAENFGESAPELSALAVALTLDGDWYGLSVVGPTERIRQHRDKHAALLVDAKARL
LAEHARG

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082359, Length=231, Percent_Identity=27.7056277056277, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786715, Length=217, Percent_Identity=24.4239631336406, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788131, Length=247, Percent_Identity=23.8866396761134, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27033; Mature: 27033

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCC
YYPTRRLQTVAAAIDATDPVVDIVHPHLVALRDASRETAVLGKIQGVSVTYLDVVESEQA
CCCHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCCCHHHHHHEECCCEEEEHHHHHHHHH
IRYTRQPGELRPLHANSIGKAIFAELASEAQQALGAQLPFERFTDATVADLAALVAQTAR
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHH
FRELGWAENFGESAPELSALAVALTLDGDWYGLSVVGPTERIRQHRDKHAALLVDAKARL
HHHHCCHHHCCCCCCCCEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHEEEEHHHHHH
LAEHARG
HHHHCCC
>Mature Secondary Structure
MDVKLVARTLDLFELFAAERRPLPLTELARLLNVPASSCLAMARTLVSRGYLYEVRKRGG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCC
YYPTRRLQTVAAAIDATDPVVDIVHPHLVALRDASRETAVLGKIQGVSVTYLDVVESEQA
CCCHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCCCHHHHHHEECCCEEEEHHHHHHHHH
IRYTRQPGELRPLHANSIGKAIFAELASEAQQALGAQLPFERFTDATVADLAALVAQTAR
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHH
FRELGWAENFGESAPELSALAVALTLDGDWYGLSVVGPTERIRQHRDKHAALLVDAKARL
HHHHCCHHHCCCCCCCCEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHEEEEHHHHHH
LAEHARG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]