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The map label for this gene is fhuB [H]

Identifier: 116689658

GI number: 116689658

Start: 1802129

End: 1804219

Strand: Direct

Name: fhuB [H]

Synonym: Bcen2424_1636

Alternate gene names: 116689658

Gene position: 1802129-1804219 (Clockwise)

Preceding gene: 116689657

Following gene: 116689659

Centisome position: 51.73

GC content: 74.89

Gene sequence:

>2091_bases
ATGACGACGTTCGCGATGCGCAAGCGCCTCGCGGCGACGGGCAGAGGGGCGACCCGCGGGCGAGCCGGCGCGATCGCGTT
CGGCCTCGTCGCGTTGACCGCGCTGCTCGCGGCGCTGCGGATCGCCCCCGATCTGCGCGTGTGGTGGGACGCGGCGCCCG
GCAGCGATGCCGCGTCGCTCGCGCACGTGTTCCTGTTCGACCTCAATCTGCCGCGCGTGGCGGCCGCGCTCGTCGCGGGC
GGCTGCCTCGGCATCGCCGGCGCGCTGTTCCAGTCGCTCACGCGCAATCCGCTCGCGTCGCCCGACCTGCTCGGCGTGAC
GGGCGGCGCCCAGCTCGGCCTGCTCGCGGCGATGCTGGTGCCGGCGCTGGCGGGCGTCGCGACGGTGCCGCTGCTGTTCG
TGTGCGGGCTCGTCGCGGCCGCGTGCGCGATCGTCGCGGCGGGCGGCTGGCGTGCGACGCCGTTGCGGCTCGTGCTCGCG
GGCAGCGTATGCATGCTGCTGTTCGCCGCGCTGTCGACACTGGTGCTCGCGTTCTTCGAGCAGAACATCGCGGGCGCCGC
GCTGTGGACCAACGGCAGCCTGTACCAGCCGGGCGCGACGGGCCTCGTGCTCGCCGCGCGCTGGCTCGTCGTGCCGCTCG
CCGCGCTGCCGTTCGTGATCCGGCCGCTGAATCCGCTCACGCTCGGCGACGATGCGGCGGCCGCGGCCGGCGTGCGCGTC
GATGCGACGCGGCTTGCCGCGACGATCGTCGCGGTCGCATTCACGAGCGTGGCCGTCAGCATCGCGGGCCCGCTGTCGTA
CGTCGGGCTCGTCGCGCCGAACCTGCTGCGCCAGGTGCGCGGCGCACGCGCGGCCCGGCTCGGCGTGCTGGTGCCGCTGT
CGGCGCTTGCCGGTGGCGCGCTCGTGCTCGTCACCGACAGCGCGGTGCTCGCGTCGGGCCTCGACGCGACGCTGTCGACC
GGCGTCGCGATCGCGCTGGTCGGCACGCCGCTGATGCTCGCGATGATCCGGCGCGGCGCCGCGTGGTCGGGCGTGCTGCA
TGCGGATGCCGAACGTACGGCGGGCGGCGGCTCGACGCGGCTCGTCGGCTGGCTCGAACGGCTCGGCTGGCCGCTGCGCA
CCGTGCTGTTCGTCATGGCGGGCGTGCTGGTGGTTTTCGTCGGCGTGTCCGCCGGCCCCGAGTGGCTGTCGCCGGCGCGC
TGGTCGGCGGCGCTGTCCGGTCACGATCCGCTCGCGCGCATGCTGATCGACCTGCGCATGCCGCGCCTGCTGTGCGCGCT
GCTCGCCGGCGCGTTGCTGGCGGTCAGCGGCGTCGCGATGCAGAGCGTCGTGCGCAATCCGCTCGCGGGCCCCGAAGTAC
TCGGCGTCACGCAGGGCGCGGGGCTCGTCACGCTGTTCGCGTTGTCGACGTGGCCGCTGATGGGTCATGTGACGCTTGCG
GCGGCGGCGCTGATCGGCGGCGGGCTGTCGCTCGCGATCACGCTCGCACTGAATCACCGGCATCGCTACGCGCCGCTCGC
GGTCGCGCTGACCGGCATCGTGATCGGCGCGTTGTGGACCACGCTCGCGCAATGGCTGATCACGCAGGAAAGCGTGCAAC
CCGCGCGTTTCGTCGTGTGGCTCGTCGGCGGCACGTATGGCCGCAGCTGGGGCGAGGTATCGATGCTGCTGCCGTGGTGC
GTGCTCGCGGTGCCGGTGTTCGCGTGGCTTGCGAAACCGCTCGACATGCTCGCGCTCGGCGACGACCAGGCGGCCGCGCT
CGGCCTGCCGGTGGCCGCGCTGCGGCCGCTCGCGCTGACGATCGCGACGCTCGCCGCGTGCGCGGCCGTCGCGGCGGTCG
GGCCGGTCGGCTTCATCGGGCTGATGGCGCCGCACGTTGCGACGATGCTCGGCGCGCGCCGGCATCGCACGCGGCTGTGG
CTCGCGGCGGCGTGCGGCGCGCTGATCCTCGGCGTCGCGGATCTCGCGGCGCGCACCGTCGTCGCGCCGCGCGAGGTGCC
GGCCGGCGTGCTGACCGCGCTGATCGGCGCGCCGTACCTGCTCGGTCTGCTGATTCTCGAGGGGCGCCGCGCCCGGCGCG
CGGGGCGATGA

Upstream 100 bases:

>100_bases
CGCATCCGCAGACGGGCGCGCCGATGTGCGTACCGGCCTACGGGCCGTCGACCGACGCCGCGCCGCAGGCGGCCGGCGTG
TTCGATCGGGATCTCGCCGT

Downstream 100 bases:

>100_bases
CGCCGGCGCTCGACGGCGCGCGCGCCACGCGCTTTTCGGCGTTCGCGCCGCAACCGTTCGCCGAGCACCTCGACATCGTC
TGGCTCGGCATGCCCGACGA

Product: iron-hydroxamate transporter permease subunit

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Ferrichrome uptake protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MTTFAMRKRLAATGRGATRGRAGAIAFGLVALTALLAALRIAPDLRVWWDAAPGSDAASLAHVFLFDLNLPRVAAALVAG
GCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVATVPLLFVCGLVAAACAIVAAGGWRATPLRLVLA
GSVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLVLAARWLVVPLAALPFVIRPLNPLTLGDDAAAAAGVRV
DATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLASGLDATLST
GVAIALVGTPLMLAMIRRGAAWSGVLHADAERTAGGGSTRLVGWLERLGWPLRTVLFVMAGVLVVFVGVSAGPEWLSPAR
WSAALSGHDPLARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLA
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLLPWC
VLAVPVFAWLAKPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVATMLGARRHRTRLW
LAAACGALILGVADLAARTVVAPREVPAGVLTALIGAPYLLGLLILEGRRARRAGR

Sequences:

>Translated_696_residues
MTTFAMRKRLAATGRGATRGRAGAIAFGLVALTALLAALRIAPDLRVWWDAAPGSDAASLAHVFLFDLNLPRVAAALVAG
GCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVATVPLLFVCGLVAAACAIVAAGGWRATPLRLVLA
GSVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLVLAARWLVVPLAALPFVIRPLNPLTLGDDAAAAAGVRV
DATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLASGLDATLST
GVAIALVGTPLMLAMIRRGAAWSGVLHADAERTAGGGSTRLVGWLERLGWPLRTVLFVMAGVLVVFVGVSAGPEWLSPAR
WSAALSGHDPLARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLA
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLLPWC
VLAVPVFAWLAKPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVATMLGARRHRTRLW
LAAACGALILGVADLAARTVVAPREVPAGVLTALIGAPYLLGLLILEGRRARRAGR
>Mature_695_residues
TTFAMRKRLAATGRGATRGRAGAIAFGLVALTALLAALRIAPDLRVWWDAAPGSDAASLAHVFLFDLNLPRVAAALVAGG
CLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLVPALAGVATVPLLFVCGLVAAACAIVAAGGWRATPLRLVLAG
SVCMLLFAALSTLVLAFFEQNIAGAALWTNGSLYQPGATGLVLAARWLVVPLAALPFVIRPLNPLTLGDDAAAAAGVRVD
ATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGALVLVTDSAVLASGLDATLSTG
VAIALVGTPLMLAMIRRGAAWSGVLHADAERTAGGGSTRLVGWLERLGWPLRTVLFVMAGVLVVFVGVSAGPEWLSPARW
SAALSGHDPLARMLIDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLAA
AALIGGGLSLAITLALNHRHRYAPLAVALTGIVIGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLLPWCV
LAVPVFAWLAKPLDMLALGDDQAAALGLPVAALRPLALTIATLAACAAVAAVGPVGFIGLMAPHVATMLGARRHRTRLWL
AAACGALILGVADLAARTVVAPREVPAGVLTALIGAPYLLGLLILEGRRARRAGR

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786347, Length=644, Percent_Identity=31.2111801242236, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1790740, Length=294, Percent_Identity=41.156462585034, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI1788004, Length=310, Percent_Identity=35.4838709677419, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786804, Length=322, Percent_Identity=34.7826086956522, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1790741, Length=282, Percent_Identity=36.8794326241135, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786805, Length=292, Percent_Identity=32.8767123287671, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 70924; Mature: 70793

Theoretical pI: Translated: 11.70; Mature: 11.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFAMRKRLAATGRGATRGRAGAIAFGLVALTALLAALRIAPDLRVWWDAAPGSDAASL
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
AHVFLFDLNLPRVAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHH
PALAGVATVPLLFVCGLVAAACAIVAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNIAGAALWTNGSLYQPGATGLVLAARWLVVPLAALPFVIRPLNPLTLGDDAAAAAGVRV
HCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
DATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCE
LVLVTDSAVLASGLDATLSTGVAIALVGTPLMLAMIRRGAAWSGVLHADAERTAGGGSTR
EEEEECCHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCEECCCHHCCCCCCHH
LVGWLERLGWPLRTVLFVMAGVLVVFVGVSAGPEWLSPARWSAALSGHDPLARMLIDLRM
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
PRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHH
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVIGALWTTLAQWLITQESVQPARFVVW
HHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
LVGGTYGRSWGEVSMLLPWCVLAVPVFAWLAKPLDMLALGDDQAAALGLPVAALRPLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHHH
IATLAACAAVAAVGPVGFIGLMAPHVATMLGARRHRTRLWLAAACGALILGVADLAARTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPREVPAGVLTALIGAPYLLGLLILEGRRARRAGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
TTFAMRKRLAATGRGATRGRAGAIAFGLVALTALLAALRIAPDLRVWWDAAPGSDAASL
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
AHVFLFDLNLPRVAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLAAMLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHH
PALAGVATVPLLFVCGLVAAACAIVAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNIAGAALWTNGSLYQPGATGLVLAARWLVVPLAALPFVIRPLNPLTLGDDAAAAAGVRV
HCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
DATRLAATIVAVAFTSVAVSIAGPLSYVGLVAPNLLRQVRGARAARLGVLVPLSALAGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCE
LVLVTDSAVLASGLDATLSTGVAIALVGTPLMLAMIRRGAAWSGVLHADAERTAGGGSTR
EEEEECCHHHHCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCEECCCHHCCCCCCHH
LVGWLERLGWPLRTVLFVMAGVLVVFVGVSAGPEWLSPARWSAALSGHDPLARMLIDLRM
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
PRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSTWPLMGHVTLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHH
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVIGALWTTLAQWLITQESVQPARFVVW
HHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
LVGGTYGRSWGEVSMLLPWCVLAVPVFAWLAKPLDMLALGDDQAAALGLPVAALRPLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHHH
IATLAACAAVAAVGPVGFIGLMAPHVATMLGARRHRTRLWLAAACGALILGVADLAARTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPREVPAGVLTALIGAPYLLGLLILEGRRARRAGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258 [H]