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The map label for this gene is nanT [H]

Identifier: 116689558

GI number: 116689558

Start: 1698288

End: 1699508

Strand: Reverse

Name: nanT [H]

Synonym: Bcen2424_1536

Alternate gene names: 116689558

Gene position: 1699508-1698288 (Counterclockwise)

Preceding gene: 116689562

Following gene: 116689557

Centisome position: 48.78

GC content: 66.91

Gene sequence:

>1221_bases
ATGAGCTGGACCCGCGAGCAACGCAACGTCACGATCGCCGCCTACCTGGGCTGGACGCTCGATGCGTTCGATTTTTTCCT
GATGGTTTTCGTGCTGAAGGACATCGCCGCGGAATTCGCGTCGACGATCCCCGCCGTCGCGTTCGCGCTCACGCTGACGC
TCGCGATGCGCCCGCTCGGCGCGCTGATCTTCGGCCGGCTCGCCGACCGCTTCGGCCGCCGCCCGACGCTGATGGTCAAC
ATCGCCTGCTATTCGCTGCTCGAACTCGCGTCGGGTTTCGCGCCGAGCCTGACCGCGCTGCTCGTGCTGCGCGCGCTGTT
CGGCATCGCGATGGGCGGCGAATGGGGCGTCGGCTCCGCGCTGACGATGGAAACCGTGCCGACCCACGCGCGCGGCTTCG
TGTCGGGGCTGCTGCAGGCCGGCTACCCGAGCGGCTATCTGCTCGCGTCCGTCGTGTTCGGCCTGTTCTACCAGACCATC
GGCTGGCGCGGGATGTTCATGGTCGGCGTGCTGCCCGCGCTGCTCGTGCTGTACGTGCGCGCACACGTGCCCGAATCGCC
GGCATGGAAACAGATGGAGAAGCGAGCGCGCCCGAGCCTCGGCGCGACGCTGAAGCAGAACTGGAAGCTCACGATCTACG
CGATCGTGCTGATGACCGCGTTCAACTTCTTCTCGCACGGCACGCAGGACCTCTATCCGACCTTCCTGCGCGAACAGCAC
CACTTCGATCCGCATACCGTGTCGTGGATCACGATCGTGCTGAACATCGGCGCGATCGTCGGCGGCCTGTCGTTCGGCAC
GATCTCGGAGCGGATCGGCCGGCGCCGCGCGATCTTCATCGCCGCGCTGATCGCGCTGCCCGTGCTGCCGCTGTGGGCGT
TCTCGAGCGGCCCGGTTGCACTCGCCGCCGGCGCGTTCCTGATGCAGATCTCGGTACAGGGCGCGTGGGGCGTGATACCG
GTTCACCTGAACGAGATCTCGCCCGACGAGATCCGTGCGACCTTCCCCGGCGTCGTCTACCAGCTCGGCAACCTGCTCGC
GTCGGGCAACGCGACGATGCAGGCGTCGCTGGCCGTGTCGAACCACGACAATTACGGCTTCGCGCTCGCGCTCGTGGCCG
GTATCGTGGCCGTCGCGATCGCCGTGCTGATCCTGTTCAGCCGCGAACGGCGCGGCATCGACATGACGCAATCGGTCAAT
ACGCGTAGCACCGTCGGGTGA

Upstream 100 bases:

>100_bases
GCGGAAGCCTACACTCGATCAGTGCCCCCGCGCCGCGCGCGAGCCGGGCCGGCATCCGCATGCCTATCGCGAACGCGCAA
GCCAACGAGGAGACCCGCAC

Downstream 100 bases:

>100_bases
ACCCGCGCGTTGCGGCACCGCATCATCGCGCGCGCCCCGCCCCGCCGTGAGCGGGTGTCGCGCTTTCCGCACCCGCACAT
CGAACTAGAGGAATTGATCC

Product: major facilitator transporter

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTLMVN
IACYSLLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQTI
GWRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRARPSLGATLKQNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLSFGTISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSNHDNYGFALALVAGIVAVAIAVLILFSRERRGIDMTQSVN
TRSTVG

Sequences:

>Translated_406_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTLMVN
IACYSLLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQTI
GWRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRARPSLGATLKQNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLSFGTISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSNHDNYGFALALVAGIVAVAIAVLILFSRERRGIDMTQSVN
TRSTVG
>Mature_405_residues
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTLMVNI
ACYSLLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQTIG
WRGMFMVGVLPALLVLYVRAHVPESPAWKQMEKRARPSLGATLKQNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQHH
FDPHTVSWITIVLNIGAIVGGLSFGTISERIGRRRAIFIAALIALPVLPLWAFSSGPVALAAGAFLMQISVQGAWGVIPV
HLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSNHDNYGFALALVAGIVAVAIAVLILFSRERRGIDMTQSVNT
RSTVG

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082404, Length=393, Percent_Identity=28.2442748091603, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI87082231, Length=195, Percent_Identity=34.3589743589744, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790550, Length=394, Percent_Identity=26.3959390862944, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788292, Length=447, Percent_Identity=25.9507829977629, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786229, Length=386, Percent_Identity=25.1295336787565, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081723, Length=341, Percent_Identity=28.7390029325513, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789941, Length=435, Percent_Identity=25.2873563218391, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788942, Length=428, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17542342, Length=135, Percent_Identity=37.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=208, Percent_Identity=24.5192307692308, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=440, Percent_Identity=27.9545454545455, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320595, Length=132, Percent_Identity=32.5757575757576, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=203, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43998; Mature: 43867

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLG
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQTIGWRGMFMVGVLPALLVLYVR
EEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AHVPESPAWKQMEKRARPSLGATLKQNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLSFGTISERIGRRRAIFIAALIALPVLPLWAFSSGPVA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVS
HHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
NHDNYGFALALVAGIVAVAIAVLILFSRERRGIDMTQSVNTRSTVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLG
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTLMVNIACYSLLELASGFAPSLTALLVLRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPTHARGFVSGLLQAGYPSGYLLASVVFGLFYQTIGWRGMFMVGVLPALLVLYVR
EEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AHVPESPAWKQMEKRARPSLGATLKQNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLSFGTISERIGRRRAIFIAALIALPVLPLWAFSSGPVA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVS
HHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
NHDNYGFALALVAGIVAVAIAVLILFSRERRGIDMTQSVNTRSTVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA