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The map label for this gene is infC [H]

Identifier: 116689498

GI number: 116689498

Start: 1630803

End: 1631273

Strand: Direct

Name: infC [H]

Synonym: Bcen2424_1476

Alternate gene names: 116689498

Gene position: 1630803-1631273 (Clockwise)

Preceding gene: 162227933

Following gene: 116689499

Centisome position: 46.81

GC content: 56.48

Gene sequence:

>471_bases
GTGCGCCTGGTCGGGATCGAGAACGAACCGCTCGGTATCGTAAAACTCGCTGACGCTTTCCGTAAATCGGAAGAACTGGA
TGTTGACCTGGTGGAGATCGCGCCGCAAGCGGTGCCGCCGGTTTGCCGTCTGATGGATTACGGCAAGTTCAAGTACCAGG
AATCGAAGAAGCAGCACGAAGCGAAGCTGAAGCAGAAGGTCATCCAGGTCAAGGAAGTCAAGTTCCGTCCGGGTACCGAT
GACGGGGATTACAACGTCAAGCTCCGCAATCTCGTGCGCTTCCTCGAAGAGGGCGACAAGACGAAGATCACGTTGCGTTT
CCGCGGCCGTGAAATGGCTCACCAGGAAATCGGTATGCGGATGCTCGAGCGTCTGCGCACGGATCTCGAGGAAGTCGGCC
AGGTCGAGCAGATGCCGAAGATGGAAGGGCGCCAGATGATCATGGTGCTCTCGCCGAAGAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCTGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCACCGCATCAACG
GTGAAATCACTGCGCCGGAA

Downstream 100 bases:

>100_bases
CGGGCCCGCGCGCCTCGCGCGCAGGTTCGACAGTGGTTCGGCGCGTTGCCCGGTCAGGGCGGCGCGCCAACGATGACGGC
GGCTGCGCAAGCGGTGCGCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLVGIENEPLGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLEEVGQVEQMPKMEGRQMIMVLSPKKKK

Sequences:

>Translated_156_residues
MRLVGIENEPLGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLEEVGQVEQMPKMEGRQMIMVLSPKKKK
>Mature_156_residues
MRLVGIENEPLGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMRMLERLRTDLEEVGQVEQMPKMEGRQMIMVLSPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=69.4267515923567, Blast_Score=206, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18214; Mature: 18214

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGIENEPLGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLEEVGQVEQMPKMEGRQMIMVLSPKKKK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRLVGIENEPLGIVKLADAFRKSEELDVDLVEIAPQAVPPVCRLMDYGKFKYQESKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEEGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLEEVGQVEQMPKMEGRQMIMVLSPKKKK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]