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The map label for this gene is lpsI [H]

Identifier: 116689487

GI number: 116689487

Start: 1619824

End: 1620528

Strand: Direct

Name: lpsI [H]

Synonym: Bcen2424_1465

Alternate gene names: 116689487

Gene position: 1619824-1620528 (Clockwise)

Preceding gene: 116689485

Following gene: 116689488

Centisome position: 46.49

GC content: 64.11

Gene sequence:

>705_bases
ATGAACAAAGTCTATCCAAGCGCGGCTGCCGCGCTGGAGGGGATCGTCCGTGACGGACAGACCTTCGCGGTGGGCGGCTT
CGGCCTGTGCGGGATTCCCGAGGCGCTGATCGCGGCGTTGCGCGATTCGGCCGTCAAGGGCATCACCTGCATCAGCAACA
ATGCGGGCGTCGACGGTTTCGGCCTCGGCCTGCTGCTGGAAACGCGCCAGATCAAGAAGATGATCTCGTCGTACGTCGGC
GAGAACAAGGAGTTCGAGCGCCAGTACCTGGCCGGCGAACTCGAGCTCGAATTCACGCCGCAGGGCACGCTCGCCGAAAA
GCTGCGCGCGGGCGGCGCGGGCATCCCCGCGTTCTTCACGAATACCGGCTACGGCACAGTGATCGCGGAAGGCAAGGAAA
CGCGCCAGTTCGGCGATCGCCACTACGTGCTCGAGCCGTCGCTGACGGCCGACGTCGCGCTCGTCAAGGCGTGGAAGGCC
GACAAGTCCGGCAACCTGATCTATCGCCGCACCGCGCGCAACTTCAACCCGATGTGCGCGATGGCCGGCAAGATCACCGT
GGTCGAAGTCGAGGAGATCGTCGAGAACGGTACGCTCGATCCGGATCAGGTCCATACGCCGGGGATCTTCGTGCAGCGCA
TCGTGCTGAACGCGACGCCCGAAAAACGCATCGAACAACGCGTCGTACGCGCGAAAGGAGACTGA

Upstream 100 bases:

>100_bases
GACGCAGGCATTGCCGCGCATGCATAGAATGGTGCGGCGGGCTTGCGCCACGTGGCGCGTGAACCGGTTTTGCTGGTTTC
CATAGAGGAAGGGACAACTG

Downstream 100 bases:

>100_bases
CATGGCCTGGAATCGTGACCAGATGGCCGCGCGCGCGGCGAAGGAACTGCAGGACGGCTTCTACGTGAACCTCGGCATCG
GCCTGCCGACGCTCGTCGCG

Product: 3-oxoacid CoA-transferase, A subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKVYPSAAAALEGIVRDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDRHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVVEVEEIVENGTLDPDQVHTPGIFVQRIVLNATPEKRIEQRVVRAKGD

Sequences:

>Translated_234_residues
MNKVYPSAAAALEGIVRDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDRHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVVEVEEIVENGTLDPDQVHTPGIFVQRIVLNATPEKRIEQRVVRAKGD
>Mature_234_residues
MNKVYPSAAAALEGIVRDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDRHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGKITVVEVEEIVENGTLDPDQVHTPGIFVQRIVLNATPEKRIEQRVVRAKGD

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=251, Percent_Identity=56.5737051792829, Blast_Score=284, Evalue=5e-77,
Organism=Homo sapiens, GI11545841, Length=238, Percent_Identity=52.9411764705882, Blast_Score=238, Evalue=3e-63,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=43.6274509803922, Blast_Score=184, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=252, Percent_Identity=56.3492063492063, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=52, Blast_Score=244, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=52, Blast_Score=244, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25263; Mature: 25263

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYPSAAAALEGIVRDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGF
CCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEEE
NTGYGTVIAEGKETRQFGDRHYVLEPSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVVEVEEIVENGTLDPDQVHTPGIFVQRIVLNATPEKRIEQRVVRAKGD
HCCCEEEEEHHHHHHCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVYPSAAAALEGIVRDGQTFAVGGFGLCGIPEALIAALRDSAVKGITCISNNAGVDGF
CCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEEE
NTGYGTVIAEGKETRQFGDRHYVLEPSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVVEVEEIVENGTLDPDQVHTPGIFVQRIVLNATPEKRIEQRVVRAKGD
HCCCEEEEEHHHHHHCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]